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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:37 AM EDT

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Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Oxygen Consumption Clear all
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Hyperbaric VO2max Study

NCT02356900
View directory record Official record
Conditions
Exercise Training
Interventions
Hyperoxic hyperbaric interval exercise training, Normoxic, normobaric, interval exercise training, Oxygen
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Short-term Effects of Caffeine and a Multi-ingredient Pre-workout on Exercise Performance

NCT07024940
View directory record Official record
Conditions
Coffee, Anthocyanins, Exercise Performance
Interventions
Ethiopian Coffee, Supplement, Water (Placebo)
Other · Dietary Supplement
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 35 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Not applicable Interventional Results available

Study of Exercise Training in Hypertrophic Cardiomyopathy

NCT01127061
View directory record Official record
Conditions
Cardiomyopathy, Hypertrophic
Interventions
Exercise training
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 80 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Stanford, California • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 20, 2026, 5:37 AM EDT
Completed No phase listed Observational

Tissue Oxygen Use With Combined Arteriovenous Noninvasive Oximetry

NCT06072755
View directory record Official record
Conditions
Oxygen Consumption
Interventions
Finger pulse oximetry probe, Transreflectance oximetry probe
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 20, 2026, 5:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance

NCT04074668
View directory record Official record
Conditions
Diabetic Kidney Disease, Type 1 Diabetes, Diabetes, Diabetes Mellitus, Diabetes Complications, Diabetic Nephropathies, Type1diabetes, Diabetes, Autoimmune, Autoimmune Diabetes, Juvenile Diabetes, Type 1 Diabetes Mellitus
Interventions
Aminohippurate Sodium Inj 20%, Iohexol Inj 300 milligrams/milliliter (mg/ml), PET/CT Scan, Renal Biopsy
Drug · Radiation · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 30 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 20, 2026, 5:37 AM EDT
Not listed No phase listed Observational

Exercise Capacity Before and After AF Ablation in Patients With HFpEF

NCT05376748
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 110 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 20, 2026, 5:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Maximal Oxygen Uptake Obtained Via Seismofit and Cardiopulmonary Exercise Test

NCT07554404
View directory record Official record
Conditions
Healthy
Interventions
VO2 Max
Other
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Pharmacokinetic/Pharmacodynamic Study of Udenafil in Adolescents

NCT02201342
View directory record Official record
Conditions
Single Ventricle Heart Disease After Fontan Surgery
Interventions
Udenafil
Drug
Lead sponsor
Mezzion Pharma Co. Ltd
Industry
Eligibility
14 Years to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 20, 2026, 5:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

O2 Consumption and Heart Rate Response to Battle Rope Exercise Protocol Versus UE Arm Bike Test in Adults With SCI

NCT03793595
View directory record Official record
Conditions
Spinal Cord Injury at T2 and Below
Interventions
Seated Battle Ropes Protocol, Seated Upper Extremity Arm Bike
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 20, 2026, 5:37 AM EDT
Completed No phase listed Observational

Validation of a Novel Oxygen Consumption Measurement Technique in Neonates

NCT03154112
View directory record Official record
Conditions
Neonatal Respiratory Failure, Congenital Heart Defect
Interventions
Measurement of oxygen consumption and caloric expenditure
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 12 Months
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 2 Interventional Results available

Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis

NCT03717896
View directory record Official record
Conditions
Diabetic Ketoacidosis
Interventions
200mg IV thiamine in 50mL 0.9% saline, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 4 Interventional Results available

Phase IV O2 Consumption Study in COPD Patients.

NCT02533505
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Budesonide 160 mcg and formoterol fumarate dihydrate 4.5 mcg Inhalation aerosol, Matching Placebo pMDI 160/4.5 μg
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
5
States / cities
Hartford, Connecticut • Boston, Massachusetts • Charlotte, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 3 Interventional Results available

24 Hour Ambulatory Cardiac Oxygen Consumption

NCT05170061
View directory record Official record
Conditions
Hypertension
Interventions
Nebivolol, Valsartan, Nebivolol/valsartan combination
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2025 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Dietary Nitrate for Heart Failure

NCT01682356
View directory record Official record
Conditions
Heart Failure, Hypertension, Pulmonary
Interventions
Beetroot juice
Dietary Supplement
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
2
States / cities
Indianapolis, Indiana • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults

NCT00572624
View directory record Official record
Conditions
Obesity
Interventions
Diet, Gastric bypass surgery
Behavioral · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 50 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 20, 2026, 5:37 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Gas Kinetics and Metabolism in Anesthesia During Non Steady State

NCT00225381
View directory record Official record
Conditions
Anesthetized Healthy Patients (ASA 1 or 2) in the Supine Position, Excluding Head, Neck and Head Surgeries, Anesthetized Patient With Severe Systemic Disease (ASA 3 or 4)
Interventions
connection of measuring device to anesthesia circuit, drawing of blood sample through an arterial line, placed according to clinical criteria by primary anesthesia team, changing operating room bed position (head down and up position), adding PEEP during anesthesia, placement of esophageal Doppler for cardiac output measurements, Humidity sensor, A mixing chamber (bymixer), Pneumotachometer cuvette, Mass spectrometer sampling port
Device · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Supplemental Oxygen on Maximal Oxygen Consumption in Patients With Chronic Obstructive Pulmonary Disease

NCT01294033
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Fractional inspired oxygen (FiO2) 0.21, Fractional inspired oxygen 0.28
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Oct 20, 2026, 5:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

BFR Training on a Bike to Augment RC Strength, Leg Strength, and VO2 Peak

NCT05344391
View directory record Official record
Conditions
Can BFR Cycling Augment Strength and VO2peak
Interventions
BFR cycling, Cycling without BFR
Other
Lead sponsor
George Fox University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 20, 2026, 5:37 AM EDT
Recruiting Phase 3 Interventional

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

NCT05918211
View directory record Official record
Conditions
Single Ventricle Heart Disease
Interventions
Udenafil, Placebo
Drug
Lead sponsor
Mezzion Pharma Co. Ltd
Industry
Eligibility
12 Years to 18 Years
Enrollment
436 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
37
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gentle Jogger and Oxygen Consumption

NCT03602365
View directory record Official record
Conditions
Physical Inactivity, Oxygen Consumption
Interventions
Gentle Jogger (GJ)
Device
Lead sponsor
Sackner Wellness Products LLC
Industry
Eligibility
25 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 2 Interventional

Nesiritide and Vo2 Max in Heart Failure Patients

NCT00240084
View directory record Official record
Conditions
Heart Failure
Interventions
nesiritide (Natrecor(TM))
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 20, 2026, 5:37 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Impact of Enhanced External Counterpulsation (EECP) on VO2 MAX

NCT02517671
View directory record Official record
Conditions
Cardiovascular Disease, Pulmonary Disease
Interventions
Enhanced External Counterpulsation (EECP)
Device
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2018 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Not applicable Interventional Results available

Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)

NCT02184169
View directory record Official record
Conditions
Transposition of the Great Vessels, Hypoplastic Left Heart Syndrome, Oxygen Consumption Based Assessment of Hemodynamics
Interventions
General Electric Healthcare E-COVX Gas Monitoring Module for VO2 Measurments, Edwards Continuous SVO2 Catheter and Monitoring System - 4.5 fr
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Day to 6 Months
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 20, 2026, 5:37 AM EDT
Completed Phase 2 Interventional Results available

Improving Ventilatory Capacity in Those With Chronic High Level SCI

NCT05041322
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Buspirone, Placebo
Drug
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 20, 2026, 5:37 AM EDT