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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Oxygen Delivery Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Comparison of Flow Regulated Nasal Oxygen Delivery System (FRNDS) Cannula and Plethysmography Belts

NCT06713213
View directory record Official record
Conditions
Respiratory Failure With Hypoxia
Interventions
Flow-regulated nasal oxygen delivery system (FRNDS)
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Use of NIRS in Preterm Population Born at Altitude

NCT04639583
View directory record Official record
Conditions
Prematurity; Extreme
Interventions
Near-infrared spectroscopy (NIRS) utilization
Device
Lead sponsor
University of New Mexico
Other
Eligibility
0 Hours to 24 Hours
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Delivery of Optimized Supersaturated Oxygen Therapy to Treat Patients With an Acute Heart Attack

NCT01630707
View directory record Official record
Conditions
Anterior Wall Acute Myocardial Infarction
Interventions
SuperSaturated Oxygen (SS02) Therapy
Device
Lead sponsor
TherOx
Industry
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
4
States / cities
Scottsdale, Arizona • Royal Oak, Michigan • Southfield, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 23, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

MoblO2 to Maintain Oxygenation

NCT07704567
View directory record Official record
Conditions
COPD (Chronic Obstructive Pulmonary Disease), Intersitital Lung Disease
Interventions
MoblO2 controls O2 flow, MoblO2 does not control flow
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
25 Years to 95 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Phase 4 Interventional

Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial Hypertension

NCT06409026
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Sotatercept
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Type 2 Diabetes and Exercise Function in Single Leg Exercises

NCT01793909
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Single Leg Exercise Training
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 70 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Jul 23, 2026, 5:01 PM EDT
Terminated Not applicable Interventional Results available

Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants

NCT05030012
View directory record Official record
Conditions
Infant, Premature, Neonatal Respiratory Distress, Oxygen Saturation, Bronchopulmonary Dysplasia
Interventions
Automated Control, Manual Control
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Salt Lake City, Utah • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Jul 23, 2026, 5:01 PM EDT
Terminated Phase 2Phase 3 Interventional

Method of Oxygen Delivery and the Effect on Transcutaneous PaCO2

NCT00135252
View directory record Official record
Conditions
Lung Diseases, Obstructive
Interventions
nasal cannula oxygen delivery, supplemental oxygen delivery by hood
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Week to 6 Months
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2008 · Synced Jul 23, 2026, 5:01 PM EDT
Completed No phase listed Observational

Monitoring of Vital Signs During Skin-to-skin Holding by Mothers of Their Preterm Babies

NCT02231801
View directory record Official record
Conditions
Other Preterm Infants
Interventions
Mother-Infant Dyad
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
30 Weeks to 35 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2015 · Synced Jul 23, 2026, 5:01 PM EDT
Terminated No phase listed Observational

Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates

NCT01735552
View directory record Official record
Conditions
Anemia of Prematurity, Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 12 Weeks
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oxygen Transport in Normobaric vs. Hypobaric Hypoxia

NCT03335917
View directory record Official record
Conditions
Hypoxia, Altitude, Exercise
Interventions
Hypoxia, Exercise
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effect of Red Blood Cell Transfusion on Brain Metabolism in Patients With Subarachnoid Hemorrhage

NCT00968227
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Vasospasm
Interventions
Red blood cell transfusion
Biological
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Transdermal Continuous Oxygen Therapy for Diabetic Foot Ulcers

NCT01291160
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Epiflo, Moist Wound Therapy
Device · Other
Lead sponsor
Neogenix, LLC dba Ogenix
Industry
Eligibility
20 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
14
States / cities
Phoenix, Arizona • Tucson, Arizona • Encinitas, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 12, 2014 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Neonatal Pulse Oximetry Sensor Study

NCT05250102
View directory record Official record
Conditions
Premature Birth
Interventions
Pulse oximeter sensors
Device
Lead sponsor
Medline Industries
Industry
Eligibility
1 Day to 28 Days
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Los Angeles, California • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Saturation Targets and Resuscitation in Preterm Trial

NCT03115463
View directory record Official record
Conditions
Oxidative Stress
Interventions
Titration of oxygen during neonatal resuscitation
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Jul 23, 2026, 5:01 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

An Alternative Way To Deliver Oxygen To People

NCT04870801
View directory record Official record
Conditions
Hypoxia
Interventions
Respirogen Micro-Oxygen
Drug
Lead sponsor
Christopher Bell
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Continuous Diffusion of Oxygen Treatment for Incision Wounds

NCT04307355
View directory record Official record
Conditions
Surgical Wound, Breast Surgery, Mammoplasty, Incision Wound
Interventions
Transcu O2®, Tegaderm, Silagen
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Live Births With Low Oxygen Blastocyst Culture

NCT00708487
View directory record Official record
Conditions
Infertility, Pregnancy Rate, Live Birth, In Vitro Fertilization
Interventions
Embryo incubator oxygen concentration
Other
Lead sponsor
Texas Health Resources
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2008 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3

NCT03333174
View directory record Official record
Conditions
Infant,Premature
Interventions
Cardiorespiratory monitoring
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 98 Days
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

A Randomized Trial of Outpatient Oxygen Weaning Strategies in Premature Infants

NCT01994954
View directory record Official record
Conditions
Premature Infants
Interventions
RHO
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Up to 37 Weeks
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
8
States / cities
Farmington, Connecticut • Lexington, Kentucky • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated May 29, 2023 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Oxygen Delivery Devices for Reversal of Altitude-Induced Hypoxemia in Normal Subjects

NCT01477450
View directory record Official record
Conditions
Hypoxemia, Hypobaric Hypoxemia
Interventions
Pulse-dose oxygen, Cylinder oxygen delivery
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional

DCS Study in Extremely Premature Newborns

NCT04367181
View directory record Official record
Conditions
Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
Interventions
Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
Device
Lead sponsor
Maria Angela Franceschini
Other
Eligibility
0 Hours to 72 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Oxygen Use During Delivery and Cord Blood Superoxide Dismutase

NCT01042262
View directory record Official record
Conditions
Oxidative Stress, Fetal Distress
Interventions
Oxygen, Placebo
Other
Lead sponsor
George Washington University
Other
Eligibility
Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 4, 2010 · Synced Jul 23, 2026, 5:01 PM EDT
Completed Phase 2Phase 3 Interventional

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity

NCT01203436
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Blindness
Interventions
Supplemental Oxygen Management, Conventional Oxygen Management
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
649 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1999
U.S. locations
9
States / cities
Palo Alto, California • New Haven, Connecticut • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2015 · Synced Jul 23, 2026, 5:01 PM EDT