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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:43 AM EDT

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Showing 1–24 of 258 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Oxygenation Clear all
Not listed No phase listed Observational

Hyperspectral Imaging Pre and Post Endovascular Intervention

NCT00768495
View directory record Official record
Conditions
Chronic Limb Ischemia, Non-Healing Ulcers
Interventions
Not listed
Lead sponsor
HyperMed
Industry
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2009 · Synced Oct 21, 2026, 7:43 AM EDT
Active, not recruiting Not applicable Interventional

Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease

NCT03562728
View directory record Official record
Conditions
Advanced Lung Disease, Lung Transplant, Extracorporeal Membrane Oxygenation
Interventions
MRP and NMES(neuromuscular electric stimulation), Standard of Care
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 21, 2026, 7:43 AM EDT
Terminated No phase listed Observational

Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation

NCT00920569
View directory record Official record
Conditions
Recirculation, Oxygenator Blood Volume, Cardiac Output, Venoarterial Extracorporeal Membrane Oxygenation, Venovenous Extracorporeal Membrane Oxygenation
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 27, 2016 · Synced Oct 21, 2026, 7:43 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Early Predictors of Necrotizing Enterocolitis in Neonates

NCT03210831
View directory record Official record
Conditions
Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 7 Days
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Suspended No phase listed Observational

Outcome Assessment in Patients Treated With Hyperbaric Oxygen Using OxyVu Tissue Oxygenation Monitoring System

NCT00768027
View directory record Official record
Conditions
Wounds
Interventions
Not listed
Lead sponsor
HyperMed
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
Long Beach, California • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 4, 2009 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
27
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oxygenation Changes After 2-month Exercise in Sedentary Older Adults With Diabetes

NCT04626453
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Oxygen Deficiency
Interventions
2-month home moderate-intensity exercise
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
60 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional

Apneic Oxygenation in the Pediatric Intensive Care Unit

NCT03374046
View directory record Official record
Conditions
Intubation Complication
Interventions
Apneic Oxygenation
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
0 Days to 17 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Vascular and Neurocognitive Health

NCT06497413
View directory record Official record
Conditions
Cognitive Decline, Cognitive Dysfunction, Alzheimer Disease, Vascular Disease, Peripheral
Interventions
Transcranial Photobiomodulation, Transcranial Photobiomodulation helmet (Neuradiant 1070 Plus) with no light administered
Device
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 21, 2026, 7:43 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Needle Free Assessment of Myocardial Oxygenation in Healthy Subjects

NCT06000540
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
RespirAct
Device
Lead sponsor
Indiana University
Other
Eligibility
45 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional

Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are Walking

NCT00985842
View directory record Official record
Conditions
Amputation, Diabetes Complications, Leg Injuries, Traumatic Amputation
Interventions
Pe-Lite and sleeve suspension socket, Total Surface bearing a socket with a sleeve suspension but without suction, Total surface bearing suction socket with a pin lock suspension, Total surface bearing suction socket with a sleeve suspension, Vacuum-assisted socket system (Harmony System, Otto Bock)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational

Cerebral Perfusion, Oxygenation, Electrical Activity

NCT00747682
View directory record Official record
Conditions
Post-Hemorrhagic Hydrocephalus
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 24, 2010 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational

Assessing Brain Injury Using Portable Magnetic Resonance Imaging (MRI)

NCT05469139
View directory record Official record
Conditions
Extracorporeal Membrane Oxygenation Complication, Acute Brain Injury
Interventions
Portable MRI acquisition
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational

Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock

NCT05426083
View directory record Official record
Conditions
Acute Coronary Syndrome, Cardiogenic Shock
Interventions
Physiological Assessment
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NATO Litter: Fluid Immersion System (FIS) Versus Traditional Mattress for Pressure Dispersion

NCT03483623
View directory record Official record
Conditions
Pressure Distribution, Military Litters, Peak Pressure Index, Total Surface Area, Tissue Perfusion
Interventions
NATO WELP combination, NATO FIS combination, RAVEN WELP combination, RAVEN FIS combination
Other
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
19 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 21, 2026, 7:43 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Microcirculatory and Tissue and Cerebral Oxygenation in Preeclampsia and Normal Pregnancy: An Observation Study

NCT02351583
View directory record Official record
Conditions
Pregnancy, Eclampsia
Interventions
CytoCam, NIRS Artinis PortaLite with OxySoft softwear
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational

MolecuLight All-in-One Oxygenation Clinical Utility

NCT07646938
View directory record Official record
Conditions
Wounds
Interventions
MolecuLightDX+ with OxySight Module
Device
Lead sponsor
MolecuLight Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Timeline
2026
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Withdrawn Not applicable Interventional

Individualized vs Low PEEP in One Lung Ventilation

NCT03569774
View directory record Official record
Conditions
One-Lung Ventilation, Obesity, Lung Diseases
Interventions
One-lung ventilation with individualized PEEP, One-lung ventilation with low PEEP
Procedure
Lead sponsor
Dionne Peacher
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting Phase 2 Interventional

Physiology of Unloading VA ECMO Trial

NCT06336655
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
IABP
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Phase 1 Interventional

Tissue Oxygenation Measurements With Modulated Light (S-FLARE)

NCT01116297
View directory record Official record
Conditions
Breast Cancer
Interventions
Imaging with S-FLARE imaging system
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting Not applicable Interventional

Transplantation of Autologously Derived Mitochondria Following Ischemia

NCT02851758
View directory record Official record
Conditions
Extracorporeal Membrane Oxygenation Complication
Interventions
autologous mitochondria transplantation
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of Isometric Exercises on Balance, Heart Rate, Pulse Ox and Blood Pressure

NCT02599727
View directory record Official record
Conditions
Exercise, Isometric
Interventions
Isometric exercises, No exercise
Other
Lead sponsor
Carrick Institute for Graduate Studies
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cape Canaveral, Florida
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite

NCT02859597
View directory record Official record
Conditions
Morbid Obesity, Noninvasive Ventilation, Deep Sedation
Interventions
High flow nasal cannula, Nasal Cannula
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

NCT05052216
View directory record Official record
Conditions
Pediatric Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
3 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 21, 2026, 7:43 AM EDT