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ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:36 AM EDT

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Showing 1–24 of 575 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: PAD - Peripheral Arterial Disease Clear all
Completed Phase 1 Interventional

A Multiple Ascending Dose Study of RO4905417 in Healthy Volunteers and Patients With Peripheral Arterial Disease (PAD).

NCT00760565
View directory record Official record
Conditions
Peripheral Arterial Disease (PAD)
Interventions
RO4905417, placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Gainesville, Florida • Cincinnati, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional

The OPC for Optimal Delivery of Paclitaxel for the Prevention of Endovascular Restenosis - Above and Below the Knee

NCT02464501
View directory record Official record
Conditions
Peripheral Arterial Disease, Cardiovascular Disease, Peripheral Vascular Disease
Interventions
Paclitaxel administration using the OPC
Other
Lead sponsor
Horizons International Peripheral Group
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
17
States / cities
Fairhope, Alabama • Jacksonville, Florida • Pensacola, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2019 · Synced Oct 19, 2026, 1:36 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Using Near-Infrared Light to Better Understand Peripheral Artery Disease

NCT07313410
View directory record Official record
Conditions
Peripheral Artery Disease (PAD)
Interventions
Not listed
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Implementation of ABI and WIfI in Rural Health Clinics

NCT04337723
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetic Foot, Diabetes Mellitus
Interventions
ABI/WIFI scoring
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Phase 1 Interventional Results available

Safety Study of Gene Therapy in Treating Critical Leg Ischemia

NCT00696124
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
VM202 2 mg, VM202 4 mg, VM202 8 mg, VM202 16 mg
Biological
Lead sponsor
Helixmith Co., Ltd.
Industry
Eligibility
20 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Phase 2 Interventional Results available

Magnetic Resonance Angiography for Peripheral Arterial Disease (PAD)

NCT00707876
View directory record Official record
Conditions
Peripheral Arterial Disease (PAD)
Interventions
ferumoxytol
Drug
Lead sponsor
AMAG Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
1
States / cities
Lexington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon

NCT03241459
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Artery Disease, Peripheral, Femoropopliteal Artery Occlusion
Interventions
Surmodics SurVeil DCB, Medtronic IN.PACT Admiral DCB
Device
Lead sponsor
SurModics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
446 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
50
States / cities
Birmingham, Alabama • Foley, Alabama • Gilbert, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD

NCT03445754
View directory record Official record
Conditions
Peripheral Artery Disease, Endothelial Dysfunction, Autonomic Imbalance
Interventions
TVS, Sham TVS
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Withdrawn Not applicable Interventional

Mind Body Program for Vascular Disease

NCT05757752
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases
Interventions
Problem Solving Therapy and Integrated Care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Phase 2 Interventional

Trial of VLTS-589 in Subjects With Intermittent Claudication

NCT00068133
View directory record Official record
Conditions
Intermittent Claudication, Peripheral Vascular Disease
Interventions
Plasmid based Gene Transfer product-VLTS-589
Genetic
Lead sponsor
Valentis
Industry
Eligibility
40 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Beverly Hills, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 19, 2026, 1:36 AM EDT
Active, not recruiting Not applicable Interventional

Telehealth to Improve Functional Status and Quality of Life in Veterans With PAD

NCT05048979
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Completed No phase listed Observational

An Evaluation of a Clinical Algorithm With Turbo-Power Following Treatment of Specific Morphologies

NCT02921542
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Laser Atherectomy
Device
Lead sponsor
Spectranetics Corporation
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Branched-Chain Amino Acid Metabolism on Limb Dysfunction in PAD

NCT03490968
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Supervised Exercise, Vascular Assessment
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
50 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional Results available

Impacts of Mitochondrial-targeted Antioxidant on Peripheral Artery Disease Patients

NCT03506633
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Artery Disease
Interventions
MitoQ
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Phase 1 Interventional

Natural Vascular Scaffold (NVS) Therapy

NCT03148808
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases, Catheterization, Peripheral
Interventions
NVS Therapy
Combination Product
Lead sponsor
Alucent Biomedical
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Columbus, Ohio • Wynnewood, Pennsylvania • Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional Results available

Low InTensity Exercise Intervention in PAD

NCT02538900
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Exercise, Attention control
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
4
States / cities
Chicago, Illinois • New Orleans, Louisiana • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 19, 2026, 1:36 AM EDT
Withdrawn No phase listed Observational

Shockwave: Disruption for A Better Fit

NCT05147363
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Shockwave Intravenous lithotripsy with a Supera stent
Device
Lead sponsor
Cardiovascular Institute of the South Clinical Research Corporation
Other
Eligibility
18 Years and older
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houma, Louisiana
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Not applicable Interventional Results available

Study Comparing Synthetic Vascular Grafts in Patients With Peripheral Artery Disease (PAD) Who Require Artery Bypass.

NCT01113892
View directory record Official record
Conditions
Peripheral Arterial Occlusive Disease
Interventions
vascular grafts
Device
Lead sponsor
Maquet Cardiovascular
Industry
Eligibility
21 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
18
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palo Alto, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 22, 2020 · Synced Oct 19, 2026, 1:36 AM EDT
Terminated Phase 2 Interventional Results available

Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial Disease

NCT02636283
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Entresto, Placebo group
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 19, 2026, 1:36 AM EDT
Active, not recruiting Not applicable Interventional Results available

LIFE-BTK PK Sub-study

NCT05208905
View directory record Official record
Conditions
Critical Limb Ischemia (CLI)
Interventions
Esprit BTK Device
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
3
States / cities
Jacksonville, Florida • South Dartmouth, Massachusetts • Bartlesville, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetics of Peripheral Artery Genomics

NCT00615121
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Oct 19, 2026, 1:36 AM EDT
Completed Phase 1Phase 2 Interventional

Safety, Efficacy, and Pharmacokinetics (PK) Study of Trans Sodium Crocetinate (TSC) in Patients With Intermittent Claudication

NCT00725881
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Trans sodium crocetinate (TSC), 0.9% normal saline
Drug
Lead sponsor
Diffusion Pharmaceuticals Inc
Industry
Eligibility
40 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
7
States / cities
Birmingham, Alabama • Santa Rosa, California • Stanford, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2011 · Synced Oct 19, 2026, 1:36 AM EDT
Withdrawn Not applicable Interventional

Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI)

NCT07175129
View directory record Official record
Conditions
Chronic Limb Threatening Ischemia
Interventions
Transverse Tibial Bone Transport, TrueLok Elevate
Procedure · Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 95 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 19, 2026, 1:36 AM EDT
Recruiting No phase listed Observational

Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System

NCT07335341
View directory record Official record
Conditions
Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis, Acute DVT of Lower Extremity, Chronic DVT of Lower Extremity, DVT, Deep Vein Thrombosis Leg, Thrombus in the Peripheral Venous Vasculature, Peripheral Arterial Disease, Acute Limb Ischemia, Lower Extremity Acute Limb Ischemia, LE ALI
Interventions
Liberant Thrombectomy System
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Naples, Florida • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 19, 2026, 1:36 AM EDT