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ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:24 AM EDT

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Showing 409–432 of 575 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: PAD - Peripheral Arterial Disease Clear all
Completed Not applicable Interventional Results available

Gamification-Augmented Home-Based Exercise for Peripheral Artery Disease

NCT04536012
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Gamification and Social Incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Revolution™ Peripheral Atherectomy System for Lower Extremity Peripheral Arterial Revascularization

NCT02961894
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Revolution™ Peripheral Atherectomy System
Device
Lead sponsor
Rex Medical
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
17
States / cities
Darien, Connecticut • Jacksonville, Florida • Lauderdale Lakes, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Pantheris Atherectomy Treatment of In-Stent Restenosis In Lower Extremity Arteries

NCT03192696
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Atherectomy Catheter
Device
Lead sponsor
Avinger, Inc.
Industry
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
12
States / cities
Jonesboro, Arkansas • Little Rock, Arkansas • San Diego, California + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 21, 2026, 8:24 AM EDT
Recruiting Not applicable Interventional

Bioresorbable Sirolimus-Eluting Scaffold Treatment for Below the Knee Disease

NCT06071429
View directory record Official record
Conditions
Chronic Limb-Threatening Ischemia
Interventions
MAGNITUDE Sirolimus-eluting Bioresorbable Scaffold, Percutaneous Transluminal Angioplasty (PTA)
Device
Lead sponsor
R3 Vascular Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
3
States / cities
New York, New York • Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Terminated Not applicable Interventional Results available

Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb Ischemia

NCT02046226
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Oxygenesys(TM) Dissolved Oxygen Dressing
Device
Lead sponsor
Halyard Health
Industry
Eligibility
21 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 12, 2015 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 1 Interventional Results available

Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)

NCT02863926
View directory record Official record
Conditions
Peripheral Artery Disease, Vascular Disease, Critical Limb Ischemia
Interventions
Injection of cBMA aspirate into the index leg
Biological
Lead sponsor
Michael Murphy
Other
Eligibility
40 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds

NCT03960463
View directory record Official record
Conditions
Surgical Wound, Diabetes, Amputation Wound, Incision Wound, Peripheral Arterial Disease, Breast Cancer, Diabetic Foot
Interventions
Transcu O2®
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 2 Interventional Results available

Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers

NCT00189540
View directory record Official record
Conditions
Arterial Occlusive Disease, Peripheral Vascular Disease, Ischemia, Ulcers
Interventions
HGF plasmid, Placebo
Genetic
Lead sponsor
AnGes USA, Inc.
Industry
Eligibility
40 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
4
States / cities
Pensacola, Florida • Indianapolis, Indiana • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon

NCT03241459
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Artery Disease, Peripheral, Femoropopliteal Artery Occlusion
Interventions
Surmodics SurVeil DCB, Medtronic IN.PACT Admiral DCB
Device
Lead sponsor
SurModics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
446 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
50
States / cities
Birmingham, Alabama • Foley, Alabama • Gilbert, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 21, 2026, 8:24 AM EDT
Active, not recruiting Not applicable Interventional

Telehealth to Improve Functional Status and Quality of Life in Veterans With PAD

NCT05048979
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 2 Interventional Results available

Patients With Intermittent Claudication Injected With ALDH Bright Cells

NCT01774097
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
ALD-301, Placebo (vehicle)
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
40 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Stanford, California • Gainesville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 21, 2026, 8:24 AM EDT
Recruiting Not applicable Interventional

Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease

NCT06308562
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Fuzzy Wale Compression Stockinet
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)

NCT04663867
View directory record Official record
Conditions
Peripheral Artery Occlusion, Peripheral Arterial Disease
Interventions
AngioSafe Peripheral CTO Crossing System
Device
Lead sponsor
AngioSafe, Inc.
Industry
Eligibility
22 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
18
States / cities
Chandler, Arizona • St. Helena, California • Darien, Connecticut + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Not yet recruiting Not applicable Interventional

Evaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers

NCT07290673
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU)
Interventions
FoundationDRS Solo, Standard of Care
Other
Lead sponsor
Samaritan Biologics
Industry
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hollywood, Florida
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Withdrawn Not applicable Interventional

Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI)

NCT07175129
View directory record Official record
Conditions
Chronic Limb Threatening Ischemia
Interventions
Transverse Tibial Bone Transport, TrueLok Elevate
Procedure · Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 95 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 21, 2026, 8:24 AM EDT
Recruiting Not applicable Interventional

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

NCT06480786
View directory record Official record
Conditions
Peripheral Arterial Disease, Painful Diabetic Neuropathy, Diabetes Mellitus, Type 2, Chronic Pain, Spinal Cord Stimulation, Chronic Pain Syndrome, Limb Pain
Interventions
Spinal cord stimulation, Sham stimulation
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Verizon mHealth Solution for Patients With Peripheral Artery Disease (PAD)

NCT02472561
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Fitbit Physical Activity Monitor, mHealth Glucometer, mHealth Blood Pressure
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Smartstep Smartphone PAD

NCT03479255
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Smartphone-enabled structured exercise therapy (SE-SET), Standard exercise therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Motivational Interviewing (MI) for African Americans With Peripheral Arterial Disease (PAD) Pilot

NCT01332058
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Motivational Interviewing
Behavioral
Lead sponsor
Tracie Collins, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2012 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional Results available

Assessment Of Vascular Health After Niacin Therapy (AVANT)

NCT02003638
View directory record Official record
Conditions
Coronary Artery Disease, Carotid Artery Disease, Peripheral Artery Disease
Interventions
Niacin, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Not applicable Interventional

Prevention Trial to Achieve Cardiovascular Targets

NCT01642355
View directory record Official record
Conditions
Coronary Artery Disease, Peripheral Arterial Disease, Hyperlipidemia, Hypertension, Diabetes, Prediabetes, Obesity
Interventions
Prevention Consult, Consult & Behavioral Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 99 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2017 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 2 Interventional Results available

Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD

NCT01785524
View directory record Official record
Conditions
Peripheral Arterial Disease, Type II Diabetes Mellitus
Interventions
Beetroot Juice (Beet-It Stamina Shot) and Exercise Training, Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
50 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 3 Interventional Results available

The DES BTK Vascular Stent System vs PTA in Subjects With Critical Limb Ischemia

NCT03551496
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Drug Eluting Stent - Below the Knee, Standard PTA Control Arm
Combination Product · Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
26
States / cities
Jonesboro, Arkansas • Little Rock, Arkansas • San Francisco, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 21, 2026, 8:24 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Remote Ischemic Preconditioning Prior to Vascular Surgery

NCT01558596
View directory record Official record
Conditions
Peripheral Arterial Disease, Vascular Surgery
Interventions
Preconditioning, Control
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2017 · Synced Oct 21, 2026, 8:24 AM EDT