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ClinicalTrials.gov public records Last synced Oct 31, 2026, 11:23 PM EDT

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Showing 385–408 of 10,293 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: PAIN Clear all
Withdrawn Not applicable Interventional

Effectiveness of Mechanical Decompression for Low Back Pain Relief

NCT00704210
View directory record Official record
Conditions
Low Back Pain
Interventions
SpineMed Table, Cert HealthSciences LLC
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 31, 2026, 11:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing Exparel & Ropivacaine for Pain Relief in Total Knee Arthroplasty

NCT02607579
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Exparel, Ropivacaine
Drug
Lead sponsor
Monmouth Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Long Branch, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Non-pharmacological Interventions for Procedural Pain in Premature Neonates

NCT02214589
View directory record Official record
Conditions
Prevention of Procedural Pain, Reduction of Procedural Pain, Biochemical Effects of Oral Dextrose
Interventions
Oral glucose, facilitated tucking, NNS, Oral glucose and NNS, Facilitated tucking and NNS
Other
Lead sponsor
Loma Linda University
Other
Eligibility
Up to 1 Month
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 31, 2026, 11:23 PM EDT
Active, not recruiting Not applicable Interventional

Development of an Intervention to Enhance Cancer Pain Management

NCT03752268
View directory record Official record
Conditions
Other Cancer
Interventions
Enhancing Cancer Pain Management
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 31, 2026, 11:23 PM EDT
Completed No phase listed Observational

Real-world Data Analysis of REN Treatment in Migraine Patients

NCT04992897
View directory record Official record
Conditions
Migraine
Interventions
Remote Electrical Neuromodulation (REN)
Device
Lead sponsor
Theranica
Industry
Eligibility
Not listed
Enrollment
12,151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 31, 2026, 11:23 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Acupuncture for Pain Management After Hip or Knee Arthroplasty

NCT00455182
View directory record Official record
Conditions
Pain, Postoperative Complications
Interventions
Acupuncture, Sham Acupuncture, Standard medical care
Procedure
Lead sponsor
HealthEast Care System
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Woodbury, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

The Back Exercises to Neutralize Disability Study

NCT02308189
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise with blood flow restriction, Exercise
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional

New Options for Treating Knee Osteoarthritis Pain

NCT05541718
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Reiki, Sham Reiki, Mindfulness Meditation
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 31, 2026, 11:23 PM EDT
Suspended Not applicable Interventional

A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain

NCT02972710
View directory record Official record
Conditions
Neck Pain
Interventions
Supine thoracic spine thrust manipulation, Seated thoracic spine thrust manipulation
Other
Lead sponsor
Northern Arizona University
Other
Eligibility
20 Years to 50 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 13, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Self Cranial Electrical Stimulation (CES) for Pain in Older Adults With Knee Osteoarthritis (Self CES for Knee Pain)

NCT04016259
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Cranial Electrical Stimulation (CES), Sham-CES
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Effects of tDCS Combined With CBI on Postsurgical Pain

NCT04199780
View directory record Official record
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions
Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Spinal Cord Stimulator Implant Study

NCT00887419
View directory record Official record
Conditions
Back Pain
Interventions
Coping Skills Training, Education
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Phase 2 Interventional Results available

Botulinum Toxin for the Management of Chronic Orchialgia

NCT02058836
View directory record Official record
Conditions
Chronic Testicular Pain
Interventions
Botox Injection, Normal saline injection
Drug · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Recruiting Not applicable Interventional

SMART Embedded Intervention for Military Postsurgical Engagement Readiness

NCT05050409
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
Brief mindfulness, Mindfulness-Oriented Recovery Enhancement (MORE), Standard care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 31, 2026, 11:23 PM EDT
Not listed Not applicable Interventional

Phoenix Thera-Lase for Treating Chronic Pain in Patients Taking Opioid on a PRN Basis

NCT02964000
View directory record Official record
Conditions
Pain
Interventions
Low level 1 Watt, Phoenix Thera-Lase System 42, Phoenix Thera-Lase System 74
Device
Lead sponsor
Phoenix Thera-lase Systems, LLC
Industry
Eligibility
25 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of NMES for Reducing Pain and Improving Functional Outcomes in Knee OA Patients

NCT03980964
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
Interventions
Active NMES
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2021 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative Nausea and Vomiting

NCT00886236
View directory record Official record
Conditions
Obesity, Morbid, Postoperative Pain, Postoperative Nausea and Vomiting
Interventions
Gabapentin, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 20, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Not listed Not applicable Interventional

Concurrent Treatment for Patients With Cervical Radiculopathy

NCT03636009
View directory record Official record
Conditions
Spinal Nerve Root Disorder Nos
Interventions
concurrent traction and neuromobilization technique, sequential traction and neuromobilization technique, active exercise program, manual therapy to cervical and thoracic spine
Other
Lead sponsor
University of Indianapolis
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mishawaka, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 19, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Risk of Falling After CFNB Versus ACB

NCT02314832
View directory record Official record
Conditions
Falls, Total Knee Arthroplasty (TKA), Osteoarthritis
Interventions
adductor canal block, femoral nerve block
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Distraction During Outpatient Pediatric Orthopedic Procedures

NCT05510232
View directory record Official record
Conditions
Fractures, Bone, Deformity; Bone
Interventions
A treatment group that will watch a non-VR video via an iPad, A treatment group that will have headset on and will watch a non-VR video, A treatment group that will be immersed in the VR game (Bear Blast) via the headset.
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
4 Years to 14 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 31, 2026, 11:23 PM EDT
Completed No phase listed Observational

Rest Before Physical Therapy in Adolescents With Active Spondylolysis and Spondylolisthesis

NCT02332200
View directory record Official record
Conditions
Spondylolysis, Spondylolisthesis, Low Back Pain
Interventions
Physical Therapy
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
Columbus, Ohio • Dublin, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Oct 31, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain

NCT00899600
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Ketamine, Normal saline
Drug · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Oct 31, 2026, 11:23 PM EDT
Completed No phase listed Observational

eNeura SpringTMS Post-Market Observational US Study of Migraine

NCT02357381
View directory record Official record
Conditions
Headache
Interventions
eNeura SpringTMS
Device
Lead sponsor
eNeura, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
7
States / cities
Phoenix, Arizona • Los Angeles, California • Stanford, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 31, 2026, 11:23 PM EDT
Not yet recruiting No phase listed Observational

CT-guided Pudendal Nerve Cryoneurolysis for Palliation of Malignancy-induced Pelvic Pain

NCT06110065
View directory record Official record
Conditions
Malignancy-induced Pelvic Pain
Interventions
CT-guided Pudendal Nerve Cryoneurolysis, Percutaneous image-guided cryoneurolysis
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 31, 2026, 11:23 PM EDT