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ClinicalTrials.gov public records Last synced Oct 30, 2026, 5:46 PM EDT

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Showing 49–72 of 10,293 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: PAIN Clear all
Not listed No phase listed Observational

Multimodal Perioperative Pain Management: ComfortSafe Program

NCT04046068
View directory record Official record
Conditions
Post-operative Pain, Post-operative Nausea and Vomiting, Respiratory Depression, Confusion Postoperative
Interventions
ComfortSafe Care
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
21 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 30, 2026, 5:46 PM EDT
Withdrawn Not applicable Interventional

Animal Assisted Intervention for Hemodialysis Outpatients

NCT06030050
View directory record Official record
Conditions
End-Stage Kidney Disease, Chronic Kidney Failure, Chronic Pain
Interventions
Animal-assisted intervention
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 30, 2026, 5:46 PM EDT
Withdrawn Phase 4 Interventional

Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision

NCT05082155
View directory record Official record
Conditions
Surgical Incision, Pain, Postoperative, Pain, Acute
Interventions
Bupivacaine 0.25%, Normal Saline
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 30, 2026, 5:46 PM EDT
Active, not recruiting No phase listed Observational

Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery

NCT03408717
View directory record Official record
Conditions
Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
Interventions
Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment
Other
Lead sponsor
KK Women's and Children's Hospital
Government
Eligibility
21 Years to 80 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional

A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain

NCT02060617
View directory record Official record
Conditions
Low Back Pain
Interventions
Patient Education, Manual therapy of the thoracolumbosacral spine and hips, Motor control exercises, Treatment-Based Classification intervention
Behavioral · Procedure
Lead sponsor
Hendricks Regional Health
Other
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Plainfield, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Microneedle Pretreatment on Topical Anesthesia

NCT02596750
View directory record Official record
Conditions
Pain
Interventions
Microneedle Roller, Sham microneedle Roller
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2018 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Low Back Pain

NCT00269321
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Manual treatment + home exercise (procedure+behavior), Supervised rehabilitative exercise+home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 28, 2013 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

NCT06366633
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
Interventions
Web-TIRELESS
Behavioral
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 30, 2026, 5:46 PM EDT
Active, not recruiting No phase listed Observational

Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation

NCT04994249
View directory record Official record
Conditions
Chronic Musculoskeletal Pain, Pain, Pain, Chronic, Joint Pain
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Impact of Mindfulness on Patients' Experience of Osteopathic Manipulation

NCT04477278
View directory record Official record
Conditions
Pain, Satisfaction, Patient
Interventions
Mindfulness Meditation, History of Osteopathy
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Phase 4 Interventional Results available

Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic Efficacy

NCT01075243
View directory record Official record
Conditions
Post-surgical Dental Pain
Interventions
Paracetamol 1000 mg, Paracetamol 650 mg, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional

Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain

NCT03597191
View directory record Official record
Conditions
Low Back Pain, Chronic Low Back Pain, Subacute Low Back Pain
Interventions
Exercises
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Oct 30, 2026, 5:46 PM EDT
Withdrawn Not applicable Interventional

A Study Comparing Two Spinal Techniques for for Cesarean Delivery Anesthesia

NCT00990574
View directory record Official record
Conditions
Hypotension, Headache
Interventions
Wiley Spinal Catheter, Spinal Anesthesia Group (SAG)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 30, 2026, 5:46 PM EDT
Completed No phase listed Observational

PROMISE Substudy to Assess For Effective Dose of Radiation (PROMISE-SAFER) Specific Aim 3b

NCT01890525
View directory record Official record
Conditions
Chest Pain, Coronary Artery Disease, Angina
Interventions
Not listed
Lead sponsor
Kaiser Permanente
Other
Eligibility
45 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Dec 6, 2019 · Synced Oct 30, 2026, 5:46 PM EDT
Not listed Phase 4 Interventional

Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures

NCT03574376
View directory record Official record
Conditions
Trauma, Trauma Injury, Pain, Acute
Interventions
Bupivacaine Liposome Injection, Bupivacaine
Drug
Lead sponsor
Chadrick Evans
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional

Pain Control After Trauma

NCT00739076
View directory record Official record
Conditions
Trauma
Interventions
Virtual Reality
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 3, 2015 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Exercise Breaks Improve Ratings of Discomfort and Fatigue in College Students (REX)

NCT04926350
View directory record Official record
Conditions
Sedentary Behavior, Fatigue, Sleepiness, Pain
Interventions
Resistance Exercise
Behavioral
Lead sponsor
Texas A&M University Kingsville
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kingsville, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Oct 30, 2026, 5:46 PM EDT
Terminated Phase 1 Interventional Results available

The Effect of Chronic Pain on Delay Discounting in Methadone Patients

NCT04473950
View directory record Official record
Conditions
Opioid-use Disorder, Chronic Pain Syndrome
Interventions
Naloxone Hydrochloride, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional Results available

Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain

NCT02461225
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Erchonia® FX-635™, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 30, 2026, 5:46 PM EDT
Enrolling by invitation No phase listed Observational

A Prospective, Single-center, Observational Clinical Outcomes Study for Vertebral Compression Fractures Treated With the OsteoPearl Biological Allograft Implants

NCT07561489
View directory record Official record
Conditions
Kyphoplasty, Vertebroplasty, Vertebral Compression Fracture, Allograft, Back Pain
Interventions
Allograft
Biological
Lead sponsor
Lenoss Medical
Industry
Eligibility
50 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 30, 2026, 5:46 PM EDT
Terminated Not applicable Interventional Results available

SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine

NCT01250418
View directory record Official record
Conditions
Pain
Interventions
Ketamine group
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional

Physiatrist Ergonomic Intervention on Work Related Musculoskeletal Pain in Surgeons

NCT05946018
View directory record Official record
Conditions
Musculoskeletal Pain, Work Related Stress, Quality of Life, Grip
Interventions
Educational video on ergonomics, Verbal physical therapy coaching sessions
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 30, 2026, 5:46 PM EDT
Terminated Phase 4 Interventional Results available

Effect of Lidocaine and Esmolol to Improve the Quality of Recovery

NCT01114997
View directory record Official record
Conditions
Pain, Constipation, Nausea, Vomiting
Interventions
Lidocaine, Esmolol, Lidocaine + Esmolol (Combo)
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Oct 30, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Post Operative Survey Through a Bi-Directional Secure Mobile Messaging System

NCT03430960
View directory record Official record
Conditions
Pain
Interventions
Phone Call, Mobile App Survey
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Oct 30, 2026, 5:46 PM EDT