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ClinicalTrials.gov public records Last synced Nov 6, 2026, 9:46 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1153–1176 of 10,302 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: PAIN Clear all

Conditions: Shoulder Arthroplasty
Interventions: Liposomal bupivacaine, Bupivacaine with adjuvants; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Ehlers-Danlos Syndrome, Pain
Interventions: Mind-body therapy; Drug
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Chronic Pain, Intractable Pain
Interventions: Commercially available Inceptiv™ neurostimulation systems; Device
Lead sponsor: Medtronic; Industry
Eligibility: 18 Years and older
Enrollment: 970 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2034
U.S. locations: 8
States / cities: Phoenix, Arizona • San Diego, California • Temecula, California + 5 more

Conditions: Computer + Fluency, Computer Only, Treatment as Usual
Interventions: Computer + Fluency, Computer Only, Treatment as Usual; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis, Knee Arthropathy
Interventions: Dorsal Root Ganglion Stimulation; Device
Lead sponsor: Kenneth B Chapman; Other
Eligibility: 21 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Chronic Pain
Interventions: EaseVRx; Device
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Neck Pain
Interventions: spine mobilizations, spine manipulations; Procedure
Lead sponsor: Newton-Wellesley Hospital; Other
Eligibility: 18 Years to 60 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 4
States / cities: San Diego, California • Colorado Springs, Colorado • Newton, Massachusetts + 1 more

Conditions: Opioid Use, Opioid Dependence, Opioid Misuse, Post-Surgical Complication
Interventions: Empowering Patient to Steer Their Pain Management After Surgery, Provider-facing Prescription Aid; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years to 89 Years
Enrollment: 711 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Pain
Interventions: Hydrocodone/Acetaminophen Extended Release, Placebo; Drug
Lead sponsor: AbbVie (prior sponsor, Abbott); Industry
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 3
States / cities: Pasadena, California • Austin, Texas • Salt Lake City, Utah

Conditions: Postoperative Pain, Bunions
Interventions: HTX-011A, Saline Placebo, HTX-011B, HTX-002, Bupivacaine HCl, HTX-009; Drug · Biological
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 430 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 5
States / cities: Anaheim, California • Bakersfield, California • Pasadena, Maryland + 2 more

Conditions: Abdominal Pain
Interventions: Ketamine, Morphine; Drug
Lead sponsor: CHRISTUS Health; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Corpus Christi, Texas

Conditions: Neuropathic Pain
Interventions: Hydromorphone; Drug
Lead sponsor: International Clinical Research Institute; Other
Eligibility: 18 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Leawood, Kansas

Conditions: Anesthesia
Interventions: Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter; Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 65 Years
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Head Cancer, Neck Cancer, Pain
Interventions: Transcutaneous Electrical Nerve Stimulation (TENS); Device
Lead sponsor: Jennifer E. Lee; Other
Eligibility: 18 Years to 90 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Sinusitis, Opioid Use, Opioid Abuse, Narcotic Use, Otolaryngologic Disease, Postoperative Pain, Pain
Interventions: OxyCODONE 5 Mg (milligram) Oral Tablet, Ibuprofen 600 Mg (milligram) Oral Tablet, Acetaminophen 650 MG (milligram) Oral Tablet; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 5
States / cities: Stanford, California • Evanston, Illinois • Rochester, Minnesota + 2 more

Conditions: Healthy, Pressure Pain Threshold, Massage
Interventions: Moderately Painful Massage; Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Ankle Sprain
Interventions: Ketoprofen Patch, Placebo Patch; Drug · Other
Lead sponsor: Hisamitsu Pharmaceutical Co., Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 25
States / cities: Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 21 more

Conditions: Pain, Chronic Disease, Prescription Opioid Abuse
Interventions: Methadone; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2005
U.S. locations: 1
States / cities: New York, New York

Conditions: Postoperative Pain
Interventions: Gabapentin, pregabalin; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: HIV Infections, Peripheral Nervous System Disease
Interventions: Mexiletine hydrochloride, Benztropine mesylate, Amitriptyline hydrochloride; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 1997
U.S. locations: 36
States / cities: Birmingham, Alabama • Los Angeles, California • San Diego, California + 23 more

Conditions: Prolapse, Urinary Incontinence, Fecal Incontinence, Bladder Pain Syndrome
Interventions: Not listed
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Pain Management, Traditional Chinese Medicine
Interventions: Traditional Chinese Medicine; Other
Lead sponsor: Chicago College of Oriental Medicine; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Major Depressive Disorder, Back Pain, Aged
Interventions: Duloxetine; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 60 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Management of Chronic Pain
Interventions: Hydromorphone Hydrochloride, Programmable Implantable pump; Drug · Device
Lead sponsor: Piramal Critical Care, Ltd.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Search by objective public record fields.

Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants

Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome

Post Market Evaluation of Real World Outcomes and Durability to Support Implantable Inceptiv™ Spinal Cord Stimulation Therapy

Evaluation of a Computerized Opioid Overdose Prevention Program

Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain

Virtual Reality - Chronic Pain At-Home Pilot Study

Comparison of the Effectiveness of Mobilization and Manipulation of the Thoracic Spine in Patients With Mechanical Neck Pain

Efficiency And Quality In Post-Surgical Pain Therapy After Discharge

Acute Pain Study Following Bunionectomy

Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control

Evaluating the Efficacy and Safety of Extended Release Hydromorphone (Exalgo) in Patients With Neuropathic Pain

Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

Transcutaneous Electrical Nerve Stimulation (TENS) and Head and Neck Cancer Pain (HNC) (TENS & HNC)

Pain Control Following Sinus Surgery

The Duration of Effects of Massage in Healthy Participants

HKT-500 in the Treatment of Adult Patients With Ankle Sprain

Medication Adherence Therapy for Opioid Abusing Pain Patients

Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy

A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection

What is the Prevalence of Female Pelvic Floor Disorders in Minnesota?

Bringing Acute and Wellness Care to Underserved Populations Using Traditional Chinese Medicine

Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults

Safety and Efficacy Study of Hydromorphone Hydrochloride by Intrathecal Administration