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ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:25 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1321–1344 of 10,302 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: PAIN Clear all

Conditions: Chronic Pain, Opioid Addiction
Interventions: Yoga, Educational Counseling; Other · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Inflammation, Pain
Interventions: Loteprednol etabonate, Vehicle of Loteprednol Etabonate; Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 407 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Pain, Postoperative
Interventions: Celecoxib, Acetaminophen, Placebo; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 45 Years
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Correction of Moderate to Severe Nasolabial Folds
Interventions: Belotero® Balance with integral lidocaine, Belotero® Balance; Device
Lead sponsor: Merz North America, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Nashville, Tennessee • Plano, Texas

Conditions: Low Back Pain
Interventions: ED Physical Therapy; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Tonsillectomy
Interventions: Standard Care, ATC Dosing, Structured Pain Management Program, As needed dosing; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 6 Years to 15 Years
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2012
U.S. locations: 1
States / cities: Madera, California

Conditions: Neuromyelitis Optica
Interventions: High Frequency Impulse Therapy, High Frequency Impulse Therapy - Sham; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Coronary Syndrome
Interventions: 99mTc-glucarate solution; Drug
Lead sponsor: Molecular Targeting Technologies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 4
States / cities: Birmingham, Alabama • New Haven, Connecticut • Cleveland, Ohio + 1 more

Conditions: Chronic Musculoskeletal Pain
Interventions: Cognitive Behavioral Therapy, Pain Reprocessing Therapy, Emotion Awareness and Expression Therapy; Behavioral
Lead sponsor: Mark A. Lumley; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • Detroit, Michigan

Conditions: Chronic Pain
Interventions: Dexmedetomidine, Placebo Saline; Drug · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Pain
Interventions: TRV130; Drug
Lead sponsor: Trevena Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 768 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 10
States / cities: Mobile, Alabama • Pasadena, California • Miami, Florida + 6 more

Conditions: Pain
Interventions: Intrathecal morphine injection, EXPAREL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 5
States / cities: Port Saint Lucie, Florida • Minneapolis, Minnesota • New Brunswick, New Jersey + 2 more

Conditions: Postoperative Dental Pain
Interventions: Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine, Placebo; Drug
Lead sponsor: Bayer; Industry
Eligibility: 16 Years and older
Enrollment: 541 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Pain, Anxiety
Interventions: Synera; Drug
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Diabetic Neuropathies
Interventions: pregabalin; Drug
Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 53
States / cities: Tuscaloosa, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 44 more

Conditions: Neuralgia, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Interventions: Magnetic Peripheral Nerve Stimulation; Device
Lead sponsor: NeuraLace Medical, Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Postoperative Pain, Shoulder Pain
Interventions: Cold Compression (CC), Ice Wrap (IW); Device · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 75 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Pain, Postoperative
Interventions: N1539, Placebo; Drug
Lead sponsor: Baudax Bio; Industry
Eligibility: 35 Years to 80 Years
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 6
States / cities: Florence, Alabama • Mobile, Alabama • Sheffield, Alabama + 3 more

Conditions: Shoulder Pain
Interventions: Lidocaine, Triamcinolone + Lidocaine; Drug
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Facial Pain
Interventions: TMS, sham TMS coil; Device
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years to 100 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Pain
Interventions: Bupivacaine SNB, EXPAREL Infiltration; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Sheffield, Alabama • Minneapolis, Minnesota

Conditions: Peripheral Neuropathy, Diabetes Mellitus, Diabetes Complications
Interventions: Thiamine; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Delayed Onset Muscle Soreness
Interventions: Loxoprofen Pain Patch, Placebo Patch, No Treatment; Drug
Lead sponsor: Lead Chemical Co., Ltd.; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Contraception, Inhalation of Nitrous Oxide
Interventions: In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac, Placebo pills, Oxygen, Nitrous Oxide; Procedure · Drug · Other
Lead sponsor: University of New Mexico; Other
Eligibility: 21 Years and older · Female only
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Albuquerque, New Mexico

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Yoga for Pain and Opioid Dependence

Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery

Preemptive Analgesia With Celecoxib for Acute Dental Pain Management

Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds

ED Physical Therapy for Chronic Low Back Pain

Home Care Management of Pediatric Pain

High Frequency Impulse Therapy for Neuropathic Pain in NMOSD

Study of 99mTc-glucarate to Detect Acute Coronary Syndrome in Chest Pain Patients.

Comparing Single-Session Therapies for Chronic Pain

Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery

A Open-label Study to Evaluate the Safety of TRV130 in Patients With Acute Pain

Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section

A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo

Study of Use of Synera for Pain During Local Skin Infiltration With Lidocaine Before Epidural Placement

Pregabalin vs Placebo in Treatment of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy

Compression and Cold Therapy on the Post-Operative Shoulder

Evaluation of Preoperative N1539 in Total Knee Arthroplasty

Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain

Transcranial Magnetic Stimulation (TMS) for Trigeminal Neuralgia

Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty

Oral Thiamine for the Treatment of Painful Diabetic Peripheral Neuropathy

Pilot Study Comparing the Efficacy and Safety of a New Pain Patch and Placebo in Delayed Onset Muscle Soreness (DOMS)

Nitrous Oxide for Pain Management During In-office Transcervical Sterilization