- Conditions
- Cryptogenic Stroke
- Interventions
- AMPLATZER PFO Occluder, Standard of Care - Medical Management
- Device · Other
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 980 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2016
- U.S. locations
- 61
- States / cities
- Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 52 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 25
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Migraine Disease, Patent Foramen Ovale
- Interventions
- Prasugrel 5mg, Transcatheter Closure of Patent Foramen Ovale
- Drug · Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Non-Small Cell Lung Cancer Stage IV
- Interventions
- Abemaciclib, Docetaxel
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 159 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 5
- States / cities
- Fayetteville, Arkansas • Wichita, Kansas • St Louis, Missouri + 2 more
- Conditions
- Migraine Disorders, Heart Septal Defects, Atrial
- Interventions
- PFO Closure with Premere investigational device., Medical management/current medications per standard of care by personal physician.
- Device · Drug
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2012
- U.S. locations
- 37
- States / cities
- Scottsdale, Arizona • Newport Beach, California • Sacramento, California + 31 more
- Conditions
- Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
- Interventions
- Flow Detection System
- Device
- Lead sponsor
- Cardiox Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 141 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more
- Conditions
- Stroke, Transient Ischemic Attack
- Interventions
- Septal Occluder Device, Antiplatelet Medical Therapy
- Device · Drug
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 664 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Foramen Ovale, Patent, Stroke, Ischemic
- Interventions
- NobleStitch™EL Suture Mediated Closure System, Amplatzer PFO Occluder
- Device
- Lead sponsor
- Nobles Medical Technologies II Inc
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 640 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Foramen Ovale, Patent, Septal Defect, Atrial, Septal Defect, Heart
- Interventions
- PFO Closure Rate, Published PFO Device Closure
- Device
- Lead sponsor
- HeartStitch.Com
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Falls Church, Virginia
- Conditions
- Stroke, PFO - Patent Foramen Ovale
- Interventions
- PFO closure with GORE® CARDIOFORM Septal Occluder
- Device
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 636 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2031
- U.S. locations
- 45
- States / cities
- Tucson, Arizona • La Jolla, California • Loma Linda, California + 39 more
- Conditions
- Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale, PIVSD - Post Infarct Muscular Ventricular Septal Defect, Valvular Heart Disease
- Interventions
- Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- Not listed
- Enrollment
- 2,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2039
- U.S. locations
- 5
- States / cities
- New Brunswick, New Jersey • New York, New York • Philadelphia, Pennsylvania + 2 more
- Conditions
- Stroke, Patent Foramen Ovale, PFO
- Interventions
- Investigational PFO Closure Device, Standard of Care PFO Closure Device
- Device
- Lead sponsor
- Occlutech International AB
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2029
- U.S. locations
- 27
- States / cities
- Phoenix, Arizona • Stanford, California • Thousand Oaks, California + 20 more
- Conditions
- Varicose Veins
- Interventions
- Polidocanol (1%) Microfoam (Varisolve), Endovenous Microfoam Occlusion
- Drug · Procedure
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 7
- States / cities
- Los Angeles, California • Durham, North Carolina • Winston-Salem, North Carolina + 4 more
- Conditions
- Patent Foramen Ovale, Stroke, Ischemic Attack, Transient
- Interventions
- STARFlex septal closure system, Best medical therapy
- Device · Drug
- Lead sponsor
- NMT Medical
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 900 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2010
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Patent Foramen Ovale (PFO)
- Interventions
- Point-of-care ultrasound
- Diagnostic Test
- Lead sponsor
- Scripps Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Patent Foramen Ovale, Intrapulmonary Arteriovenous Anastamosis
- Interventions
- Sildenafil, Placebo
- Drug · Other
- Lead sponsor
- University of Oregon
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Stroke, Patent Foramen Ovale
- Interventions
- AMPLATZER™ PFO Occluder
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 1,214 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 78
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Chandler, Arizona + 63 more
- Conditions
- Migraine, Aura, Patent Foramen Ovale
- Interventions
- BioSTAR Septal Repair Implant System, Sham Procedure
- Device · Procedure
- Lead sponsor
- NMT Medical
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 610 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 2
- States / cities
- Stamford, Connecticut • Seattle, Washington
- Conditions
- Ischemic Brain Injury, Stroke, Healthy Individual, Patent Foramen Ovale (PFO), Neurovascular Injury
- Interventions
- Not listed
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- Not listed
- Enrollment
- 750 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Stroke, Transient Ischemic Attack
- Interventions
- Antithrombotic treatment, percutaneous device closure of PFO
- Drug · Device
- Lead sponsor
- Insel Gruppe AG, University Hospital Bern
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2021
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • Springfield, Massachusetts • Tyler, Texas
- Conditions
- Pulmonary Embolism (PE), Right-to-Left Shunt, Stroke, Atrial Septal Defects, Patent Foramen Ovale (PFO), Pulmonary Arteriovenous Malformation
- Interventions
- Not listed
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 256 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke
- Interventions
- Encore PFO closure device, FDA-approved PFO closure device
- Device
- Lead sponsor
- Encore Medical Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2030
- U.S. locations
- 8
- States / cities
- Little Rock, Arkansas • La Jolla, California • Tampa, Florida + 5 more
- Conditions
- Migraine, Patent Foramen Ovale, PFO - Patent Foramen Ovale
- Interventions
- Actual device PFO closure, Thienopyridine (clopidogrel or prasugrel), Sham device PFO closure
- Device · Drug
- Lead sponsor
- W.L.Gore & Associates
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 15
- States / cities
- Phoenix, Arizona • Los Angeles, California • Santa Barbara, California + 11 more
- Conditions
- PFO, PFO - Patent Foramen Ovale, Cryptogenic Stroke, Patent Foramen Ovale, PFO-associated Stroke
- Interventions
- Recross P3 Occluder (P3O) System
- Device
- Lead sponsor
- Recross Cardio, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2031
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Gainesville, Florida • Boston, Massachusetts + 2 more
- Conditions
- Foramen Ovale, Patent
- Interventions
- Aspirin, Cardiovascular Implantable Device (CIED), Gore Cardioform Septal Occluder
- Drug · Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota