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Showing 1–24 of 1,626 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: PTSD Clear all
Not listed Not applicable Interventional

Online and Mobile Mindfulness Intervention to Reduce Distress

NCT04035304
View directory record Official record
Conditions
PTSD
Interventions
Mindfulness Coach
Other
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional

The Mobile PTSD Coach App in Acute Injury Survivors

NCT03247179
View directory record Official record
Conditions
Chronic Pain, Acute Pain Due to Trauma, Posttraumatic Stress Disorder
Interventions
PTSD Coach mobile application
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2019 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional

Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder

NCT02990793
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive Symptoms
Interventions
Active MeRT Treatment, Sham MeRT Treatment
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
18 Years to 65 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Costa Mesa, California • Long Beach, California • San Diego, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Phase 2 Interventional Results available

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

NCT03282123
View directory record Official record
Conditions
PTSD
Interventions
Midomafetamine, Manualized therapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
12
States / cities
North Hollywood, California • San Francisco, California • Boulder, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders

NCT01631682
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anxiety Disorder
Interventions
Propranolol, Reactivation, Mifepristone, Intranasal oxytocin
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional

Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings

NCT00974402
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Jul 20, 2026, 6:44 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

NCT06624137
View directory record Official record
Conditions
OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions
Serotonergic Psychedelic, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Hamden, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional

tDCS and Inhibitory Control in PTSD

NCT06100731
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
tDCS
Device
Lead sponsor
Gopalkumar Rakesh
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional Results available

Neuroimaging the Impact of Treatment on Neural Substrates of Trust in Post-Traumatic Stress Disorder (PTSD)

NCT01244477
View directory record Official record
Conditions
Stress Disorders, Post Traumatic, Trust
Interventions
Group CPT-C
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 50 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Jul 20, 2026, 6:44 PM EDT
Recruiting Not applicable Interventional

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

NCT05843695
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anxiety Disorders
Interventions
iTCBT-I, iTCBT-G, TAU
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Phase 1 Interventional

A Clinical Trial for Post Traumatic Stress Disorder

NCT00554177
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
Medicane (mifepristone), Placebo
Drug
Lead sponsor
Antonia New
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional

PTSD Treatment and Emotion Regulation Skills Training for Veterans With Military Sexual Trauma (PE+ER)

NCT04792775
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety Disorders, Mental Disorder, Traumatic Stress Disorder
Interventions
PE+ER
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care

NCT01401101
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
PCM, MEU
Other
Lead sponsor
RAND
Other
Eligibility
18 Years to 65 Years
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
7
States / cities
Jersey City, New Jersey • Far Rockaway, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Jul 20, 2026, 6:44 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Creative Arts Program to Reduce Burnout in Healthcare Professionals

NCT04276922
View directory record Official record
Conditions
Burn-Out Syndrome, Post-Traumatic Stress Disorder, Depression, Anxiety
Interventions
Visual Arts, Music, Dance/Movement, Writing/Poetry, Control
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 85 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional Results available

Messy Memories: Mobile Application Therapy Following Critical Illness

NCT05849454
View directory record Official record
Conditions
Critical Illness, Psychological Distress, Health Behavior
Interventions
Messy Memories Intervention
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 20, 2026, 6:44 PM EDT
Terminated Not applicable Interventional

Blood Pressure, Heart Rate Variability & Sleep in Veterans With PTSD

NCT01920451
View directory record Official record
Conditions
Insomnia, Posttraumatic Stress Disorder, Hypertension, Cardiovascular Disease
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTI)
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Phase 4 Interventional Results available

Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems

NCT02504931
View directory record Official record
Conditions
PTSD, Alcohol Use Disorder
Interventions
Sertraline, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Jul 20, 2026, 6:44 PM EDT
Not listed Not applicable Interventional

Forgiveness-Based Writing to Prevent Post-Traumatic Stress Disorder (PTSD) in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans

NCT00861666
View directory record Official record
Conditions
Stress Disorders, Traumatic, Anxiety Disorders, PTSD
Interventions
Forgiveness-Based Writing
Behavioral
Lead sponsor
South Central VA Mental Illness Research, Education & Clinical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2009 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional Results available

Care Outcomes for Chiropractic Outpatient Veterans

NCT03254719
View directory record Official record
Conditions
Low Back Pain, PTSD, Depression, Anxiety
Interventions
Study assessments
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated May 17, 2020 · Synced Jul 20, 2026, 6:44 PM EDT
Recruiting Phase 2 Interventional

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

NCT05959434
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use Disorder
Interventions
Cognitive Processing Therapy + Relapse Prevention, Relapse Prevention
Behavioral
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Charleston, South Carolina • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional

Prevention of Postpartum Traumatic Stress (PTSD) in Mothers With Preterm Infants.

NCT01307293
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive behavior therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2014 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Phase 3 Interventional

Telemental Health and Cognitive Processing Therapy for Female Veterans With Military-related PTSD

NCT02362477
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Processing Therapy in-person, Cognitive Processing Therapy through videoteleconference
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Feb 12, 2015 · Synced Jul 20, 2026, 6:44 PM EDT
Recruiting Not applicable Interventional

Promoting Improved Functioning Among People Experiencing Stressful Situations

NCT06482567
View directory record Official record
Conditions
Acute Stress Reaction
Interventions
iCOVER, Physical Presence with Reassurance
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Belmont, Massachusetts • Worcester, Massachusetts • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Jul 20, 2026, 6:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Cognitive, Exposure, and Skills Group Manualized Treatments in Operations Iraqi (OIF)/Operation Enduring Freedom (OEF) Female Veterans

NCT02069873
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
16-Week Group Treatment
Behavioral
Lead sponsor
New Mexico VA Healthcare System
Federal
Eligibility
19 Years to 75 Years · Female only
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 23, 2014 · Synced Jul 20, 2026, 6:44 PM EDT