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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:04 PM EDT

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Showing 49–72 of 94 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pain, Procedural Clear all
Not yet recruiting Not applicable Interventional

Virtual Reality (VR) Audiovisual Distraction to Reduce Pain and Anxiety for Prone Pain Procedures

NCT07779083
View directory record Official record
Conditions
Procedural Pain, Procedural Anxiety
Interventions
Virtual Reality (VR) Audiovisual Distraction
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 23, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional

Breaking Fasts Ahead of Cardiac Caths

NCT06996639
View directory record Official record
Conditions
Stable Angina (SA), Unstable Angina (UA), NSTEMI - Non-ST Segment Elevation MI
Interventions
Non-Fasting, Fasting
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 23, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional

RCT of Pain Perception With Fast and Slow Tenaculum Application

NCT05458037
View directory record Official record
Conditions
Pain, Acute, Pain, Procedural
Interventions
Speed of tenaculum application
Procedure
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 23, 2026, 2:04 PM EDT
Terminated No phase listed Observational

HF10 Treatment of Chronic Knee Pain

NCT04020211
View directory record Official record
Conditions
Chronic Pain Post-Procedural
Interventions
Senza HF10 Therapy
Device
Lead sponsor
Nevro Corp
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Greenfield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Oct 23, 2026, 2:04 PM EDT
Not yet recruiting No phase listed Observational

Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study

NCT07848529
View directory record Official record
Conditions
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris, Non ST Elevation Myocardial Infarction (NSTEMI)
Interventions
Biomarker testing
Diagnostic Test
Lead sponsor
Baim Institute for Clinical Research
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Lavender Aromatherapy Spine Procedure Study

NCT04156009
View directory record Official record
Conditions
Spine Injuries and Disorders, Pain, Back
Interventions
Activated Lavender Elequil aromatabs® (#372), Unactivated Lavender Elequil aromatabs® (#372)
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 85 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 23, 2026, 2:04 PM EDT
Not listed Not applicable Interventional

Virtual Reality for Alleviation of Peripheral IV Placement-Associated Discomfort

NCT03740607
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain, Perioperative Care
Interventions
Virtual reality, Peripheral intravenous catheter placement
Device · Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Pediatric Pain Optimization After Tonsillectomy

NCT05244226
View directory record Official record
Conditions
Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
Interventions
Fentanyl/Hydromorphone, Methadone
Drug
Lead sponsor
Duke University
Other
Eligibility
3 Years to 17 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 23, 2026, 2:04 PM EDT
Terminated Not applicable Interventional

Peri-procedural Smoking Cessation Program in Patients With Chronic Pain

NCT04605744
View directory record Official record
Conditions
Chronic Pain, Smoking
Interventions
Smoking cessation counseling
Behavioral
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 23, 2026, 2:04 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Lavender Aromatherapy to Decrease Anxiety/Pain Perception During Office Hysteroscopy

NCT06316934
View directory record Official record
Conditions
Anxiety, Pain, Procedural
Interventions
Lavandula angustifolia, Aura Cacia, Placebo
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 23, 2026, 2:04 PM EDT
Terminated Phase 3 Interventional

A Study of Oral Codeine Sulfate in Pediatric Patients With Post-procedural Pain

NCT01676493
View directory record Official record
Conditions
Pain
Interventions
Codeine
Drug
Lead sponsor
Roxane Laboratories
Industry
Eligibility
2 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Oct 23, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional

Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion

NCT07288047
View directory record Official record
Conditions
Abortion, First Trimester, Pain Management, Pain After Surgery, Satisfaction, Satisfaction With Care, Anxiety After Surgery
Interventions
VR headset, Usual Care
Device · Other
Lead sponsor
Study Investigator
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 23, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cervical Preparation for Same-Day Dilation & Evacuation

NCT06799052
View directory record Official record
Conditions
Abortion, Second Trimester, Procedural Pain, Procedural Complication
Interventions
Transcervical single-balloon catheter, Synthetic osmotic dilators
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial

NCT01269307
View directory record Official record
Conditions
Sedation
Interventions
1:1 ketamine-propofol mixture sedation, Propofol Sedation
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional Results available

Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults

NCT02410707
View directory record Official record
Conditions
Joint Dislocation, Perianal Abscess, Abscess
Interventions
Nitrous Oxide arm, Propofol, Oxygen
Drug
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2020 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Active vs Passive Distraction on Procedural Pain in the Pediatric Emergency Department

NCT01960166
View directory record Official record
Conditions
Pain Response
Interventions
Active Distraction, Passive Distraction
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
2 Years to 18 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide Use in Minor Procedures

NCT01911351
View directory record Official record
Conditions
Laceration, Abscess
Interventions
Nitrous Oxide
Drug
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
3 Years to 12 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2016 · Synced Oct 23, 2026, 2:04 PM EDT
Terminated Not applicable Interventional

Local Anesthesia Before Bulkamid Injection

NCT06043063
View directory record Official record
Conditions
Stress Urinary Incontinence, Intrinsic Sphincter Deficiency
Interventions
Topical lidocaine, EMLA cream, Periurethral block
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Phase 3 Interventional

A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)

NCT00417469
View directory record Official record
Conditions
Facial Wrinkles
Interventions
NADGL
Device
Lead sponsor
Genzyme, a Sanofi Company
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Timeline
2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Oct 23, 2026, 2:04 PM EDT
Completed No phase listed Observational

Evaluation of Pain and Discomfort in the Cardiac Catheterization Lab

NCT04490369
View directory record Official record
Conditions
Patient Comfort
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain

NCT03797703
View directory record Official record
Conditions
Hemorrhoids
Interventions
Lidocaine Hydrochloride 2% gel enema
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Comparison of Compounded Topical Anesthetics

NCT06569537
View directory record Official record
Conditions
Procedural Pain
Interventions
Lidocaine topical, BLT
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Acupuncture for Vasectomy Pre-procedural Anxiety and Pain Control in the Primary Care Setting

NCT03938415
View directory record Official record
Conditions
Acupuncture, Pain, Postoperative, Vasectomy
Interventions
Acupuncture, Standardized pre-procedure medications
Procedure · Other
Lead sponsor
Matthew Snyder
Federal
Eligibility
25 Years and older · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 23, 2026, 2:04 PM EDT
Completed Not applicable Interventional Results available

Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children

NCT01669642
View directory record Official record
Conditions
Abscess, Fracture
Interventions
Ketamine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 17 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 23, 2026, 2:04 PM EDT