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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pain Relief Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intramuscular Ketorolac Versus Oral Ibuprofen for Pain Relief in First Trimester Suction Curettage

NCT01595282
View directory record Official record
Conditions
Pain
Interventions
Ketorolac, Ibuprofen
Drug
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Sep 21, 2026, 6:34 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

NCT05868993
View directory record Official record
Conditions
Post Operative Pain
Interventions
Dose of 0.5% Ropivacaine
Drug
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional

Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions

NCT05980104
View directory record Official record
Conditions
Chronic Pain, Marfan Syndrome, Vascular Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome
Interventions
Empowered Relief
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Sep 21, 2026, 6:34 PM EDT
Terminated Phase 2 Interventional Results available

Resveratrol Trial for Relief of Pain in Pseudoachondroplasia

NCT03866200
View directory record Official record
Conditions
Pseudoachondroplasia
Interventions
resveratrol, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Phase 4 Interventional Results available

Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

NCT03726268
View directory record Official record
Conditions
Opioid Use, Pain, Postoperative
Interventions
Methadone, Fentanyl, Hydromorphone, Morphine, Sufentanil
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
907 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 21, 2026, 6:34 PM EDT
Not listed Phase 4 Interventional

Pain Relief After Hiatal Hernia Repair Surgery

NCT04936711
View directory record Official record
Conditions
Shoulder Pain, Hiatal Hernia
Interventions
Resteck Shiatsu Neck and Back Massager, Marcaine
Device · Drug
Lead sponsor
Norton Thoracic Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional

Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention

NCT07335159
View directory record Official record
Conditions
Pain, Acute Pain, Chronic Pain, Pain Management
Interventions
Pain Psychoeducation, Mindfulness
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Phase 2 Interventional Results available

Dopamine Receptor Agonist Therapy for Pain Relief in Women Suffering From Endometriosis: A Pilot Study

NCT02542410
View directory record Official record
Conditions
Endometriosis
Interventions
Cabergoline, Norethindrone acetate
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 40 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 21, 2026, 6:34 PM EDT
Not yet recruiting Not applicable Interventional

Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain Relief

NCT07501676
View directory record Official record
Conditions
Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF), Uterine Fibroids, Pelvic Pain, Pain Management
Interventions
TUNES (Transmucosal Uterosacral Electrical Stimulation), Sham TUNES Device
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
28 Years to 52 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 21, 2026, 6:34 PM EDT
Not listed Phase 2 Interventional

Efficacy of Celecoxib 200mg in Relieving Pain and Walking Dysfunction in Osteoarthritis of the Knee

NCT00597415
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
celecoxib, placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
45 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Beachwood, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 17, 2008 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Jet Lidocaine for Pain Relief During Needle Insertion in a Pediatric Emergency Department

NCT00681902
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
5 Years to 19 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2009 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Phase 4 Interventional Results available

Post-operative Dental Pain Study Comparing Analgesic Efficacy

NCT01082081
View directory record Official record
Conditions
Post-surgical Dental Pain
Interventions
Paracetamol 1000 mg, Paracetamol 500 mg, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 45 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Austin, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Sep 21, 2026, 6:34 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Pain Relief After PrimaryTKA

NCT05751421
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Zynrelef (Bupivacaine 60 MG / Meloxicam 1.8 MG) Per 2.3 ML Extended Release Solution, Bupivacaine HCl 0.5% Injectable Solution, primary total knee replacement
Drug · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Sep 21, 2026, 6:34 PM EDT
Recruiting No phase listed Observational

Quantify the Degree of Pain Relief of Pelvic Congestion Syndrome Following Gonadal Vein Embolization

NCT03794466
View directory record Official record
Conditions
Pelvic Congestive Syndrome, Pelvic Pain
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional

Acupuncture Relief for Chronic Neck Pain

NCT03859011
View directory record Official record
Conditions
Neck Pain, Posterior
Interventions
Acupuncture
Other
Lead sponsor
5 Element Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 21, 2026, 6:34 PM EDT
Not listed Phase 4 Interventional

Tablet vs. Liquid Suspension Ibuprofen in the Relief of Pain

NCT01681667
View directory record Official record
Conditions
Pharyngitis
Interventions
Ibuprofen
Drug
Lead sponsor
Albany Medical College
Other
Eligibility
12 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional

Mindfulness and Chronic Low Back Pain

NCT03354585
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
mindfulness training, non-mindfulness training, book-listening
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Phase 2Phase 3 Interventional

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

NCT02542384
View directory record Official record
Conditions
Post Abdominal Surgery Pain
Interventions
CR845 IV 1 mcg/kg, CR845 IV 0.5 mcg/kg, Placebo IV
Drug
Lead sponsor
Cara Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
23
States / cities
Sheffield, Alabama • New Haven, Connecticut • Bradenton, Florida + 20 more
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional Results available

Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain

NCT04156802
View directory record Official record
Conditions
Chronic Pain, Chronic Lower Back Pain, Back Pain, Opioid Use, Opiate Dependence, Pain, Chronic, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Interventions
Real TBS to the mPFC, Sham TBS to the mPFC, Real TBS to the MC, Sham TBS to the MC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Not applicable Interventional Results available

Vectors Post Market: A Study to Assess Pain Relief Using Spinal Cord Stimulation

NCT03345472
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulation System
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
20
States / cities
La Mesa, California • Orange, California • Wilmington, Delaware + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 21, 2026, 6:34 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Comparison of UGSB and GA to IV Narcotics and GA for Post-Op Pain in Children With Supracondylar Fractures.

NCT02056288
View directory record Official record
Conditions
Supracondylar Fractures
Interventions
Fentanyl, Ropivacaine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
2 Years to 17 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Phase 3 Interventional Results available

Trial of Extended Release Bupivacaine for Pain Relief After Surgery

NCT02574520
View directory record Official record
Conditions
Post Operative Pain
Interventions
SABER-Bupivacaine (Part 1), SABER-Bupivacaine (Part 2), Saline Placebo, Bupivacaine HCl
Drug
Lead sponsor
Durect
Industry
Eligibility
18 Years and older
Enrollment
399 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
21
States / cities
Florence, Alabama • Sheffield, Alabama • Arcadia, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Sep 21, 2026, 6:34 PM EDT
Completed Phase 4 Interventional

Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes

NCT02008591
View directory record Official record
Conditions
Laboring Women Requesting Neuraxial Labor Analgesia
Interventions
Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 21, 2026, 6:34 PM EDT
Enrolling by invitation Not applicable Interventional

Empowered Relief: A One-Time Session to Help Postpartum Women Manage Ongoing Pain After Cesarean Delivery

NCT07090018
View directory record Official record
Conditions
Chronic Pain, Cesarean Section Complications
Interventions
Empowered Relief
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 21, 2026, 6:34 PM EDT