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ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:01 AM EDT

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Showing 409–432 of 954 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pain Syndrome Clear all
Completed No phase listed Observational Accepts healthy volunteers

Observational Study of Control Participants for the MAPP Research Network

NCT01098292
View directory record Official record
Conditions
Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
615 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
8
States / cities
Birmingham, Alabama • Los Angeles, California • Stanford, California + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 24, 2026, 2:01 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

NCT04845217
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
Peppermint oil, Coconut Oil
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

Physical Therapy Versus Steroid Injection for Shoulder Impingement Syndrome

NCT01190891
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Manual Physical Therapy, Corticosteroid Injection
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Apr 29, 2016 · Synced Oct 24, 2026, 2:01 AM EDT
Recruiting No phase listed Observational

Time to BBVNA Relief

NCT07433634
View directory record Official record
Conditions
Low Back Pain, Vertebrogenic Pain Syndrome, Basivertebral Nerve Ablation
Interventions
Basivertebral nerve ablation
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Guilford, Connecticut • New Haven, Connecticut • Old Saybrook, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Completed No phase listed Observational

Pain Evaluation and Treatment

NCT00362167
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
4 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 24, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional

STABLE Pilates for Hypermobility

NCT07464093
View directory record Official record
Conditions
Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS), Hypermobile Spectrum Disorder
Interventions
Pilates, Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Withdrawn No phase listed Observational

Post-Breast Procedure Pain Syndrome Study

NCT01114984
View directory record Official record
Conditions
Breast, Mastectomy, Segmental
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2015 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Lidocaine Patch 1.8% for Moderate to Severe Pain From Carpal Tunnel Syndrome

NCT04245371
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Lidocaine 1.8%, Placebo
Drug
Lead sponsor
John Papakonstantinou, MD
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function

NCT03285464
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Triplanar Rotary Resistance
Other
Lead sponsor
High Point University
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2018 · Synced Oct 24, 2026, 2:01 AM EDT
Active, not recruiting Not applicable Interventional

Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI)

NCT05649384
View directory record Official record
Conditions
Acute Chest Pain, NSTEMI - Non-ST Segment Elevation MI
Interventions
European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm, European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm
Diagnostic Test
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older
Enrollment
64,374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Subjective Observational Study of Patients Using Transdermal Cream Medication And/Or Transdermal Patches With Or Without Oral Non-Narcotic Medications

NCT03768011
View directory record Official record
Conditions
Pain, Chronic, Pain, Joint, Pain Syndrome
Interventions
transdermal cream and or patch
Combination Product
Lead sponsor
Data Collection Analysis Business Management
Other
Eligibility
18 Years to 64 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Land O' Lakes, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 24, 2026, 2:01 AM EDT
Not yet recruiting Phase 2 Interventional

NAC-REPAIR for Post-surgical Pain

NCT07227649
View directory record Official record
Conditions
Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal, Dupuytren Contracture, Morton Neuroma, Tarsal Tunnel Syndrome, Plantar Fasciopathy, Peroneal Nerve Entrapment
Interventions
NAC, NAC 0mg/day (Placebo)
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Suspended Not applicable Interventional

Lyme Disease Patients With Memory Problems

NCT03500770
View directory record Official record
Conditions
Lyme Disease
Interventions
Transcranial Direct Current Stimulator
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Oct 24, 2026, 2:01 AM EDT
Recruiting Phase 2Phase 3 Interventional

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

NCT07276542
View directory record Official record
Conditions
Phantom Limb Syndrome With Pain
Interventions
IM ketamine in dose finding and then continuation
Drug
Lead sponsor
The Ketamine Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
4
States / cities
Sacramento, California • San Anselmo, California • Santa Monica, California + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acceptance and Commitment Therapy for Aging People Living With HIV in Chronic Pain

NCT03699020
View directory record Official record
Conditions
HIV/AIDS, Chronic Pain
Interventions
Acceptance and Commitment Therapy (ACT), Chronic Pain Education
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 24, 2026, 2:01 AM EDT
Terminated No phase listed Observational

Change in Pain and Quality of Life Following SCS for Chronic Pain

NCT03421951
View directory record Official record
Conditions
Pain, Chronic, Pain, Radiating, Pain, Back, Pain Syndrome
Interventions
Not listed
Lead sponsor
KM Clinical Research Group
Industry
Eligibility
18 Years to 85 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murrieta, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An Investigation Into the Efficacy of a Botanical Supplement to Provide Period Relief

NCT05845970
View directory record Official record
Conditions
Menstrual Pain, Premenstrual Syndrome
Interventions
Pamprin Botanicals, Pamprin Botanicals + Pamprin Menstrual Pain Relief
Other · Combination Product
Lead sponsor
Focus Consumer Healthcare
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 24, 2026, 2:01 AM EDT
Active, not recruiting No phase listed Observational

Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

NCT05675436
View directory record Official record
Conditions
Sickle Cell Anemia, Sickle Cell Thalassemia, Sickle Cell Pain, Hbss, Hbsc, Sickle Beta Thalassemia, Sickle Beta Zero Thalassemia, Sickle Cell Syndrome Variant
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
16 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain

NCT04009837
View directory record Official record
Conditions
Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
Interventions
Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
60 Years to 85 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Newark, Delaware • Durham, North Carolina • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Phase 3 Interventional Results available

The Effect of Long-Acting Mesalamine on Post-Infective Irritable Bowel Syndrome- A Pilot Study

NCT01412372
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Mesalamine, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 31, 2020 · Synced Oct 24, 2026, 2:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study

NCT01616992
View directory record Official record
Conditions
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interventions
Bupivacaine
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Akron, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Oct 24, 2026, 2:01 AM EDT
Suspended Not applicable Interventional

Mindfulness Intervention for Individuals With HIV and Chronic Pain

NCT06481501
View directory record Official record
Conditions
Chronic Pain, HIV Infections
Interventions
ONE Mindfulness-Oriented Recovery Enhancement
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 24, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

Does Improving Vagal Tone Increase Mitochondrial Bioenergetics

NCT03931330
View directory record Official record
Conditions
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Dyspepsia, Functional Abdominal Pain Syndrome
Interventions
Percutaneous neurostimulation
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
12 Years to 18 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Oct 24, 2026, 2:01 AM EDT
Terminated Phase 2 Interventional Results available

Safety and Efficacy of FSD201 for the Treatment of Chronic Pain Associated With Idiopathic MCAS (MCAD)

NCT05652907
View directory record Official record
Conditions
Mast Cell Activation Syndrome, Mast Cell Activation Disorder Idiopathic
Interventions
FSD201, Placebo
Drug
Lead sponsor
Quantum Biopharma
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Weldon Spring, Missouri • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 24, 2026, 2:01 AM EDT