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Conditions: Carpal Tunnel Syndrome
Interventions: Not listed
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: St Louis, Missouri

Conditions: Carpal Tunnel Syndrome
Interventions: lidocaine patch 5%; Drug
Lead sponsor: Endo USA Inc., a Keenova Therapeutics Company; Industry
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Delirium, Confusion, Mental Status Change, Back Pain, Hip Pain Chronic, Chest Pain, Asthma, COPD, Cellulitis, Soft Tissue Infections, Cough, Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism, Dyspnea, Electrolyte Metabolism Abnormal, Fever, Failure to Thrive, Weakness, Protein-Calorie Malnutrition, Headache, Neck Pain, Hypoxia, Pneumonia, Sepsis, Syncope, Vomiting, Diarrhea, Leg Pain, Abdominal Pain
Interventions: Diagnostic Uncertainty Educational Curriculum, Diagnostic Timeout, Patient Diagnostic (Dx) Questionnaire, Enhancements to Epic-integrated Quality & Safety Dashboard; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Abdominal Pain, Functional Gastrointestinal Disorders
Interventions: Apple iPod Shuffle; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 8 Years to 12 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pain, Chronic, Irritable Bowel Syndrome, Symptom Cluster
Interventions: Home-based taVNS intervention; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 29 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Patellofemoral Pain Syndrome
Interventions: transcranial direct current stimulator; Device
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years to 45 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Burns, Knee Injuries, Opioid Use, Pain
Interventions: Opioid Use 90-Days Post Treatment; Behavioral
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 0 Years to 18 Years
Enrollment: 980 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Urinary Frequency/Urgency, Bladder Irritable, Bladder Pain Syndrome
Interventions: Mirabegron; Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 89 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Metatarsalgia, Hyperkeratotic Callus, Corns, Fat Pad Syndrome
Interventions: Juvederm Voluma; Device
Lead sponsor: Schoenhaus, Jodi, DPM; Individual
Eligibility: 40 Years to 75 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boca Raton, Florida

Conditions: Overactive Bladder, Bladder Pain Syndrome, Migraine Disorders, Overactive Bladder Syndrome, Overactive Detrusor, Migraine, Interstitial Cystitis
Interventions: Ubrogepant, Rimegepant, Atogepant, Eptinezumab, Fremanezumab, Galcanezumab, Erenumab, Botulinum toxin A; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: CRPS (Complex Regional Pain Syndromes)
Interventions: Infrared Imaging; Other
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
Interventions: Cardiac Computed Tomography; Radiation
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 368 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Sickle Cell Disease
Interventions: Morphine, Nubain; Drug
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 6 Years to 19 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Interstitial Cystitis
Interventions: LP-08 80mg, Normal saline, LP-08 20mg; Drug
Lead sponsor: Lipella Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Pelvic Floor Disorders, Pelvic Pain, Pelvic Organ Prolapse, Pelvic Floor Muscle Weakness, Pelvic Pain Syndrome
Interventions: Bloom Pod; Device
Lead sponsor: Sword Health, SA; Industry
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 50,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2032
U.S. locations: 1
States / cities: Draper, Utah

Conditions: Chronic Female Pelvic Pain Syndrome (Disorder)
Interventions: Mindfulness counseling; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interventions: Metoprolol Tartrate Oral Tablet, Placebo Oral Tablet, No intervention- observational sub-study; Drug · Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Evanston, Illinois • Richmond, Virginia

Conditions: Trigger Point in Trapezius Muscle
Interventions: Dry Needling, Sham Treatment; Procedure
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Restless Legs Syndrome
Interventions: equal parts of 0.5% plain Marcaine and 2% lidocaine mixed with 0.8 mg Depo-medrol/4% absolute alcohol in a total injection volume of 1 ml, Normal saline - 1ml; Drug
Lead sponsor: Lowcountry Infectious Diseases; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Opioid Use, Postpartum Disorder, Chronic Pain Syndrome
Interventions: Gabapentin, Placebo; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
Interventions: SOMA pain manager smartphone application; Device
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Myofacial Pain, Pain, Neck, Pain, Back, Cervical Fusion
Interventions: Trigger point injection with bupivacaine, Trigger point injection with normal saline, Lidocaine skin wheal; Drug
Lead sponsor: George Washington University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Irritable Bowel Syndrome, Cyclical Vomiting Syndrome, Ulcerative Colitis, Vulvodynia, Crohn's Disease
Interventions: Not listed
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 55 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Persistent Spinal Pain Syndrome
Interventions: Pain pump, Bupivacain 0.625%/Fentanyl 2mcg/ml, Spinal Cord Stimulator (SCS); Device · Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 30 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

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Bilateral vs Unilateral CTR

Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome

Improving Safety of Diagnosis and Therapy in the Inpatient Setting

Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders

Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain

Opioid Laws and Pediatric Use

Mirabegron for the Treatment of Pain Motivated Urinary Frequency and Urgency in Women

Pressure Offloading Injectible System With the Use of Juvederm Voluma in the Foot

Migraine Medication Effects on Urinary Symptoms

Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome

Rule Out Myocardial Infarction by Computer Assisted Tomography

Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally

Evaluation of Intravesical LP08 in Patients With Interstitial Cystitis/Painful Bladder Syndrome

Digital Care Programs for Female Pelvic Health

The Impact of Integrative Medicine on Patient-Reported Outcomes in Management of Chronic Pelvic Pain

Interstitial Cystitis: Examination of the Central Autonomic Network

The Impact of Dry Needling on Electrophysiological and Ultrasound-based Biomarkers for Myofascial Pain

Neuroma Injections to Treat Restless Legs Syndrome - RCT

Prevention of Persistent Opioid Use in Mothers

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Trigger Point Injections in Anterior Cervical Surgery

Multi Modal Imaging: An MRI Study to Investigate Differences in the Structure and the Function of the Brain at Rest.

Patient Preference and Long-term Outcomes in Persistent Spinal Pain Syndrome: A Prospective Study Comparing Spinal Cord Stimulation to Intrathecal Drug Delivery.