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ClinicalTrials.gov public records Last synced Oct 12, 2026, 2:11 PM EDT

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Showing 193–216 of 356 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pain and Anxiety Clear all
Withdrawn Not applicable Interventional

Technology-Based Distractions for Minor Procedures

NCT06924814
View directory record Official record
Conditions
Anxiety, Procedural Anxiety
Interventions
Standard of Care, Immersive technology
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 12, 2026, 2:11 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Healthy Children and Virtual Reality Mediation of Simulated Pain

NCT06854991
View directory record Official record
Conditions
Acute Pain, Experimental Pain in Healthy Human Participants, Children, Adolescents
Interventions
Active VR-PAT, Passive VR-PAT, iPad
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Determining the Efficacy of Essential Oil Aromatherapy in Children Undergoing Port Access

NCT05696899
View directory record Official record
Conditions
Anxiety and Fear, Pain
Interventions
STILL QuickTAB Medipack blended scent aromatherapy, manufactured by Soothing Scents
Other
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 18 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional Results available

Nonpharmacologic Reduction of Periprocedural Distress and Drug Use

NCT03328208
View directory record Official record
Conditions
Dental Anxiety, Dental Pain, Drug Use, Opioid Use
Interventions
Comfort Talk® app, White Noise app
Other
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study of a Modified Yoga Program for Elders

NCT04343625
View directory record Official record
Conditions
Depression, Anxiety, Fatigue, Pain, Chronic, Sleep
Interventions
Modified yoga class
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

NCT05374096
View directory record Official record
Conditions
Postoperative Pain, Acute, Ventral Hernia, Hernia Abdominal Wall, Surgery, Anxiety
Interventions
Patient-Chosen Music, Placebo
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 12, 2026, 2:11 PM EDT
Enrolling by invitation Not applicable Interventional

VR for Steroid Joint Injections - Feasibility

NCT07778069
View directory record Official record
Conditions
Acute Pain, Procedural Anxiety, Juvenile Idiopahtic Arthritis
Interventions
VR-PAT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 12, 2026, 2:11 PM EDT
Terminated Not applicable Interventional

Use of Sucrose to Relieve Pain During Eye Exams in Infants

NCT00161694
View directory record Official record
Conditions
Apnea of Prematurity, Retinopathy of Prematurity, Pain
Interventions
sucrose solution
Dietary Supplement
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
5 Weeks and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional Results available

A Pilot Trial to Assess the Impact of Acupuncture on Post-mastectomy Pain, Nausea, Anxiety and Ability to Cope

NCT02122796
View directory record Official record
Conditions
Breast Cancer
Interventions
Acupuncture
Other
Lead sponsor
Allina Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Effects of Live Music on the Perception of Noise in the SICU: A Patient, Caregiver, and Medical Staff Environmental Study

NCT02269527
View directory record Official record
Conditions
Pain, Anxiety, Stress
Interventions
Live music
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 12, 2026, 2:11 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness

NCT05394545
View directory record Official record
Conditions
Chronic Pain, Anxiety, Depression, Sleeplessness
Interventions
Nu-V3
Device
Lead sponsor
Nu-Life Solutions
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Schaumburg, Illinois • Greenwood, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 12, 2026, 2:11 PM EDT
Not listed Not applicable Interventional

The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catastrophizing, Kinesiophobia, and Pain in Patients With Chronic Low Back Pain

NCT05571215
View directory record Official record
Conditions
Chronic Low-back Pain, Catastrophizing Pain, Kinesiophobia
Interventions
Transcranial Direct Current Stimulation, Pain Neuroscience Education
Device · Behavioral
Lead sponsor
High Point University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Mindfulness Intervention in Reducing Anxiety in Patients Who Have Been Treated for Gynecologic Cancer

NCT02518308
View directory record Official record
Conditions
Anxiety, Cancer Survivor, Cognitive Impairment, Depression, Distress, Fatigue, Malignant Female Reproductive System Neoplasm, Pain, Sexual Dysfunction
Interventions
Mindfulness-Based Stress Reduction
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional Results available

An Innovative Tailored Intervention for Improving Children's Postoperative Recovery (WebTIPS)

NCT03730259
View directory record Official record
Conditions
Anxiety, Pain, Postoperative Behavior
Interventions
Web-based Tailored Intervention Preparation for Surgery
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Year to 12 Years
Enrollment
1,274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Orange, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes

NCT03925168
View directory record Official record
Conditions
End Stage Renal Disease, Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder, Compliance, Patient, Compliance, Medication, Mood, Pain, Energy Supply; Deficiency, Quality of Life, Blood Pressure, Heart Rate Fast
Interventions
Music therapy
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
New Orleans, Louisiana • Terrytown, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

VR Ultrasound Guided Breast Localization

NCT04251507
View directory record Official record
Conditions
Breast Neoplasm Female
Interventions
Oculus Go Virtual Reality Goggles
Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Lavender Aromatherapy Spine Procedure Study

NCT04156009
View directory record Official record
Conditions
Spine Injuries and Disorders, Pain, Back
Interventions
Activated Lavender Elequil aromatabs® (#372), Unactivated Lavender Elequil aromatabs® (#372)
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 85 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Phase 4 Interventional Results available

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

NCT01502644
View directory record Official record
Conditions
Chronic Low Back Pain, Degenerative Disc Disease, Depression, Anxiety
Interventions
Oxycodone, Morphine, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Controlled Substance Treatment Agreements in an Internal Medicine Residents' Clinic

NCT02244099
View directory record Official record
Conditions
Anxiety, Chronic Pain, Opioid Use, Unspecified
Interventions
Controlled Substance
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Oct 12, 2026, 2:11 PM EDT
Active, not recruiting Not applicable Interventional

Neurotechnology Following Traumatic Brain Injury

NCT03649958
View directory record Official record
Conditions
Post-Concussion Symptoms, Insomnia, Pain, Chronic, Depressive Symptoms
Interventions
HIRREM-SOP or Cereset, Cereset 2x
Device
Lead sponsor
Brain State Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Healing Touch on Sleep

NCT01870076
View directory record Official record
Conditions
Elective Reconstructive Surgery Population
Interventions
Healing Touch, Healing Touch, Sham, Control, Presence
Behavioral
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
5 Years to 25 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 12, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers

NCT06985784
View directory record Official record
Conditions
Head and Neck Carcinoma
Interventions
Interview, Medical Device Usage and Evaluation, Questionnaire Administration, Virtual Technology Intervention
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Exploring the Effect of Aromatherapy

NCT07155876
View directory record Official record
Conditions
Anxiety, Labor Pain, Nausea and Vomiting
Interventions
Aromatherapy plus standard of care, Standard of Care Only
Other
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 12, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Virtual Reality (VR) for Prone Pain Procedures

NCT05615675
View directory record Official record
Conditions
Virtual Reality, Anxiety, Pain
Interventions
Virtual Reality Headset
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 12, 2026, 2:11 PM EDT