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Conditions: Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia, Major Depressive Disorder, Persistent Depressive Disorder (Dysthymia)
Interventions: Mindful Self-Compassion; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Anxiety Disorders
Interventions: Threat of shock; Device
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 921 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2022
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety, OCD, Phobia, Agoraphobia, Generalized Anxiety, Generalized Anxiety Disorder, Selective Mutism, Separation Anxiety, Social Anxiety, Social Anxiety Disorder, Panic Disorder
Interventions: Exposure Therapy; Behavioral
Lead sponsor: Bradley Hospital; Other
Eligibility: 5 Years to 18 Years
Enrollment: 379 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Riverside, Rhode Island

Conditions: Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Social Phobia, Panic Disorder, Agoraphobia, Major Depressive Disorder
Interventions: Mindful Self-Compassion; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety, Generalized Anxiety Disorder, Panic Disorder, Panic Attacks, Panic With Agoraphobia
Interventions: Standard SPACE, Bibliotherapy, low therapist contact SPACE; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 17 Years
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anxiety Disorder, Panic Disorder
Interventions: Clinical vestibular tests; Procedure
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2000
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Major Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder and Agoraphobia
Interventions: Transdiagnostic Behavior Therapy, Cognitive Processing Therapy for PTSD, Cognitive Behavioral Therapy for MDD, Cognitive Behavioral Therapy for Panic Disorder; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Panic Disorder, Agoraphobia
Interventions: Intensive panic control treatment without parent involvement, Intensive panic control treatment with parent involvement, Waitlist control; Behavioral · Other
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 12 Years to 17 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Panic Disorder With Agoraphobia
Interventions: Cognitive Therapy, Capnometry-Assisted Respiratory Training, In-vivo exposure; Behavioral
Lead sponsor: Southern Methodist University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia, Obsessive Compulsive Disorder (OCD), Panic Disorder (With or Without Agoraphobia)
Interventions: Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A); Behavioral
Lead sponsor: Andrew Wiese; Other
Eligibility: 7 Years to 17 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
Interventions: Lenses containing prismatic correction, Lenses not containing prismatic correction; Device
Lead sponsor: Vision Specialists of Birmingham; Other
Eligibility: 14 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Birmingham, Michigan

Conditions: Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Generalized Anxiety Disorder, Separation Anxiety, Panic Disorder, Panic Disorder With Agoraphobia, Panic Attacks
Interventions: Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship; Behavioral · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 13 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Post Traumatic Stress Disorder, Agoraphobia, Simple Phobia
Interventions: Mindfulness-Based Stress Reduction, Waitlist; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety, OCD, Phobia, Agoraphobia, Generalized Anxiety, Generalized Anxiety Disorder, Selective Mutism, Separation Anxiety, Social Anxiety, Social Anxiety Disorder, Panic Disorder, Pediatric Disorders
Interventions: Team-delivered, exposure-based CBT; Behavioral
Lead sponsor: Bradley Hospital; Other
Eligibility: 5 Years to 18 Years
Enrollment: 501 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: East Providence, Rhode Island

Conditions: Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia, Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions: Float pool, Float chair; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 60 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Anxiety Disorders, Trauma, Generalized Anxiety Disorder, Panic Disorder, Agoraphobia, Illness Anxiety Disorder, Social Anxiety Disorder, Posttraumatic Stress Disorder, Acute Stress Disorder, Adjustment Disorder With Anxious Mood
Interventions: Capnometry-Guided Respiratory Intervention, Psycho-Education; Device · Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Panic Disorder, Agoraphobia
Interventions: Cognitive behavior therapy, Paroxetine or other medication - algorithm used; Behavioral · Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years and older
Enrollment: 379 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2004
U.S. locations: 4
States / cities: New Haven, Connecticut • Boston, Massachusetts • New York, New York + 1 more

Conditions: Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder, Panic Disorder, Panic Attacks, Panic Disorder (With or Without Agoraphobia), Phobia, Specific
Interventions: Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 17 Years
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anxiety Disorders, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Agoraphobia
Interventions: Mindfulness-Based Stress Reduction, Escitalopram; Other · Drug
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Boston, Massachusetts • New York, New York

Conditions: Generalized Anxiety Disorder, Agoraphobia, Panic Disorder, PostTraumatic Stress Disorder, Social Anxiety Disorder, Major Depressive Disorder
Interventions: Floating, Comparison; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Tulsa, Oklahoma

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Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

Expectation of Unpleasant Events in Anxiety Disorders

Improving Access to Child Anxiety Treatment

Mindful Self-Compassion for Anxiety Disorders and Depression

Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder

Vestibular Dysfunction In Adult Patients With Panic Disorder With or Without Agoraphobia

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

Effectiveness of Intensive Cognitive Behavioral Therapy in Treating Adolescent Panic Disorder and Agoraphobia

Mechanisms of Treatment Change in Panic Disorder and Agoraphobia

Stepped Care Treatment for Anxiety Resilience

Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria

Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli

Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings

Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

Treatment of Panic Disorder: Long Term Strategies

Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

Treatments for Anxiety: Meditation and Escitalopram

Examining the Effects of Reduced Environmental Stimulation on Anxiety