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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:36 PM EDT

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Showing 1537–1560 of 2,538 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Parasomnia Clear all
Withdrawn Phase 4 Interventional

Butrans for Treatment of Restless Legs Syndrome

NCT02138357
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
buprenorphine transdermal delivery system (BTDS), Placebo for BTDS patch
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 29, 2026, 4:36 PM EDT
Recruiting Not applicable Interventional

Training in Evidence-based Treatments in Psycho-Oncology

NCT05674357
View directory record Official record
Conditions
Distress, Emotional, Depression, Anxiety, Fatigue, Pain, Insomnia
Interventions
Individualized Evidence-Based Therapy in Cancer (Patients and Caregivers), Training in Individualized Evidence-Based Therapy in Cancer (Therapists)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Interventions for Seniors With Apnea

NCT01422863
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Oct 29, 2026, 4:36 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Sleep Actigraphy in Postural Tachycardia Syndrome (POTS)

NCT00692471
View directory record Official record
Conditions
Postural Tachycardia Syndrome, Orthostatic Intolerance, Sleep Disorders
Interventions
Actigraphy Watch (motion sensors) with light sensors - ActiWatch from Minimitter
Device
Lead sponsor
Satish R. Raj
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Music, Sleep and Dementia Study

NCT04157244
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Insomnia, Hypersomnia, Cognitive Impairment, Cognitive Decline, Mild Cognitive Impairment, Frontotemporal Dementia, Neurocognitive Disorders, Vascular Dementia, Sleep Disorder, Memory Impairment
Interventions
Tailored music listening intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 110 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 1 Interventional

New Pharmacological Treatment for Obstructive Sleep Apnea

NCT00108498
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
mirtazapine
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 29, 2026, 4:36 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Cereset Research For Chronic Nausea

NCT05229107
View directory record Official record
Conditions
Nausea, Gastroparesis, Stress, Anxiety, Hyperarousal, Quality of Life, Vomiting, Heart Rate Variability
Interventions
Cereset Research
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 4 Interventional Results available

Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic Insomnia

NCT00492232
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Ramelteon and zolpidem, Placebo and zolpidem
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
41
States / cities
Hot Springs, Arkansas • Anaheim, California • Fountain Valley, California + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2010 · Synced Oct 29, 2026, 4:36 PM EDT
Active, not recruiting Not applicable Interventional

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

NCT04801771
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Inspire Upper Airway Stimulation (UAS) System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
10 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Cincinnati, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 29, 2026, 4:36 PM EDT
Completed No phase listed Observational

Sleep & Postoperative Delirium in Hispanic/ Latino Patients After Cardiothoracic Surgery

NCT04786899
View directory record Official record
Conditions
Delirium in Old Age, Sleep Disturbance, Circadian Rhythm Sleep Disorder
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Oct 29, 2026, 4:36 PM EDT
Recruiting Phase 4 Interventional

Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

NCT02630121
View directory record Official record
Conditions
Sleep Apnea, Chronic Nasal Congestion
Interventions
Oxymetazoline Hydrochloride, Placebo
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 29, 2026, 4:36 PM EDT
Withdrawn Not applicable Interventional

Vasculaire Leg Compression Device for the Treatment of Restless Legs Syndrome - A Prospective Clinical Study

NCT01861652
View directory record Official record
Conditions
Restless Legs Syndrome,, Restless Legs,, Ekbom Syndrome
Interventions
Venous Health Systems Vasculaire Leg Compression Device
Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2015 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 3 Interventional

Sequential Compression Devices for Treatment of Restless Legs Syndrome

NCT00479531
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
AirCast Sequential Compression Device
Device
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Sleep Disorders Center, Walter Reed Army Medical Center, District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2007 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blue Blockers at Night and Insomnia Symptoms

NCT02698800
View directory record Official record
Conditions
Insomnia, Sleep
Interventions
Blue blocking (BB) lenses, Clear lenses
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 2 Interventional

Effects Of GW679769 On Sleep Onset And Maintenance,And Next Day Functioning In The Elderly And Non-elderly With Primary Insomnia

NCT00280436
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Insomnia
Interventions
GW679769
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
26
States / cities
Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 21 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bonafide Sleep Supplement for Menopausal Women With Impaired Sleep

NCT07839299
View directory record Official record
Conditions
Sleep Disturbances
Interventions
S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
Dietary Supplement
Lead sponsor
Bonafide Health
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Harrison, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 1 Interventional Results available

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

NCT05094271
View directory record Official record
Conditions
OSA, Sleep Apnea, Obstructive Sleep Apnea, Alzheimer Disease
Interventions
Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air
Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years to 85 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 29, 2026, 4:36 PM EDT
Terminated Phase 3 Interventional Results available

The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea

NCT03745898
View directory record Official record
Conditions
Heart Failure, Central Sleep Apnea
Interventions
Oxygen, Room Air
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
26
States / cities
Tucson, Arizona • Stanford, California • New Haven, Connecticut + 20 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 29, 2026, 4:36 PM EDT
Terminated Phase 4 Interventional Results available

Burden of Obstructive Sleep Apnea in Stroke (BOSAST)

NCT00952211
View directory record Official record
Conditions
Stroke, Obstructive Sleep Apnea
Interventions
CPAP, CPAP at sub-therapeutic pressure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 85 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 3 Interventional Results available

Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep

NCT03679884
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Daridorexant 10 mg, Daridorexant 25 mg, Daridorexant 50 mg, Placebo
Drug
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
18 Years and older
Enrollment
804 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
53
States / cities
Birmingham, Alabama • Glendale, Arizona • Tucson, Arizona + 47 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Not applicable Interventional

The Effect of a Lighting Intervention on Sleep in Parkinson Disease

NCT05771558
View directory record Official record
Conditions
Parkinson Disease, Sleep Disturbance
Interventions
Tailored Lighting Intervention (TLI), Actigraph
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 29, 2026, 4:36 PM EDT
Enrolling by invitation Not applicable Interventional

Pain & Reward Neuromodulation of CNS Circuits

NCT07525063
View directory record Official record
Conditions
Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 29, 2026, 4:36 PM EDT
Completed Phase 2 Interventional

Efficacy Study of LY2422347 to Treat Insomnia

NCT00259311
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
LY2422347, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
24 Years to 75 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
22
States / cities
Phoenix, Arizona • Anaheim, California • Burbank, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2007 · Synced Oct 29, 2026, 4:36 PM EDT
Not listed Not applicable Interventional

e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions

NCT02087293
View directory record Official record
Conditions
Diabetes, Depression, Insomnia, Hypertension
Interventions
Intervention arm - automated call and phone-based pharmacist counseling
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
38,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 29, 2026, 4:36 PM EDT