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ClinicalTrials.gov public records Last synced Oct 31, 2026, 11:51 PM EDT

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Showing 1729–1752 of 2,538 matching trials from the live ClinicalTrials.gov search.
Conditions
Insomnia
Interventions
Lemborexant, Lemborexant-matched placebo, Zolpidem tartrate, Zolpidem-matched placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
55 Years and older
Enrollment
1,006 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
60
States / cities
Jasper, Alabama • Glendale, Arizona • Little Rock, Arkansas + 49 more
Conditions
REM Sleep Behavior Disorder, Parkinson Disease
Interventions
Sodium Oxybate, Placebo
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
40 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Insomnia
Interventions
Cognitive Behavior Therapy for Insomnia, Internet-Based Intervention, Medical Device Usage and Evaluation, Questionnaire Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Chronic Insomnia
Interventions
CBTI app intervention, Physical Activity intervention
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
21 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Completed Phase 4 Interventional Results available

Muscle Relaxation for Pediatric Adenotonsillectomy

NCT06225466
Conditions
Tonsillectomy
Interventions
Rocuronium, Sugammadex, Anesthesia without neuromuscular blockade
Drug · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
2 Years to 12 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Not applicable Interventional

Improving Sleep In Midlife Women

NCT07337915
Conditions
Poor Sleep Quality
Interventions
HealthyHabits1, HealthyHabits2, Snack 2, Snack 1
Behavioral · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Obstructive Sleep Apnea (OSA), Down Syndrome
Interventions
ato-oxy, Oxygen
Drug
Lead sponsor
University of Arizona
Other
Eligibility
6 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
5
States / cities
Tucson, Arizona • San Diego, California • Miami, Florida + 2 more
Completed Not applicable Interventional Accepts healthy volunteers

TranQuill™ Sling Snoreplasty for Snoring and Mild Obstructive Sleep Apnea:

NCT02364518
Conditions
Snoring, Obstructive Sleep Apnea
Interventions
Snoreplasty
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Sleep Apnea, Obstructive Sleep Apnea
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
North Haven, Connecticut
Conditions
Asthma, Sleep Apnea
Interventions
CPAP machine as a result of sleep study
Device
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Denver, Colorado
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Sleep and Circadian Treatments for Shift Workers

NCT03813654
Conditions
Shift-Work Sleep Disorder, Shift-Work Related Sleep Disturbance
Interventions
8-h Afternoon-Evening Sleep, 8-h Free Sleep
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
50 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 4 Interventional Results available

Improving Sleep Quality in Heart Failure

NCT03307005
Conditions
Sleep Disturbance, Heart Failure
Interventions
Zolpidem Tartrate, Placebo oral capsule
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 79 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Restless Legs Syndrome, Iron Deficiency Anemia
Interventions
Ferumoxytol intravenous, Ferrous sulfate
Drug
Lead sponsor
Auerbach Hematology Oncology Associates P C
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Differences in Efficacy Between Nasal and Oronasal Masks in the Treatment of OSA With CPAP

NCT01909674
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Switch CPAP mask type
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders, Excercise
Interventions
exercise intervention, counseling intervention, Educational Intervention, laboratory biomarker analysis, questionnaire administration, study of socioeconomic and demographic variables, fatigue assessment and management, quality-of-life assessment, Fitness testing
Behavioral · Other · Procedure
Lead sponsor
Canadian Cancer Trials Group
Network
Eligibility
18 Years and older
Enrollment
889 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2026
U.S. locations
3
States / cities
Detroit, Michigan • Lebanon, New Hampshire • Chapel Hill, North Carolina
Recruiting Not applicable Interventional

Sleep Promotion Program Primary Care

NCT06240325
Conditions
Sleep, Sleep Disturbance, Insufficient Sleep
Interventions
SPP, Sleep Psychoeducation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Insomnia
Interventions
Sleep Parent Training (SPT), Sleep Parent Education (SPE)
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
3 Years to 7 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Cleveland, Ohio • Columbus, Ohio
Conditions
Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2
Interventions
TAK-360, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 71 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
20
States / cities
Chula Vista, California • Santa Ana, California • Colorado Springs, Colorado + 15 more
Withdrawn No phase listed Observational Accepts healthy volunteers

Apollo Remote Observational Sleep Study

NCT05260489
Conditions
Sleep Quality, Heart Rate
Interventions
Not listed
Lead sponsor
Apollo Neuroscience, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Sleep Disturbance, Sleep, Depression, Suicide
Interventions
Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Enrolling by invitation Phase 1Phase 2 Interventional

DAW2020 on OSA Endotypic Traits

NCT04538755
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Placebo oral capsule, DAW2020 oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Human Immunodeficiency Virus, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Diego, California
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiologic Correlates of Hypersomnia

NCT01719315
Conditions
Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy, Primary Insomnia
Interventions
Acoustical slow wave induction
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 60 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin