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ClinicalTrials.gov public records Last synced Nov 9, 2026, 12:56 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2353–2376 of 2,544 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Parasomnia Clear all

Conditions: Sleep Initiation and Maintenance Disorders
Interventions: Valerian root extract; Dietary Supplement
Lead sponsor: University of Washington; Other
Eligibility: 55 Years to 80 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Restless Legs Syndrome
Interventions: buprenorphine transdermal delivery system (BTDS), Placebo for BTDS patch; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 25 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Cancer, Fatigue, Insomnia
Interventions: Therapeutic Massage; Procedure
Lead sponsor: Floyd Memorial Hospital and Health Services; Other
Eligibility: 18 Years and older · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New Albany, Indiana

Conditions: Tobacco Use Cessation, Sleep Disorders
Interventions: Bupropion, Transdermal Nicotine Patch, Placebo Bupropion, Placebo transdermal nicotine patch; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Menlo Park, California

Conditions: Obstructive Sleep Apnea
Interventions: ApneaLink Sleep Screener; Device
Lead sponsor: ResMed; Industry
Eligibility: 18 Years and older
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Central Sleep Apnea, Heart Failure
Interventions: Not listed
Lead sponsor: Respicardia, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Saint Cloud, Minnesota • San Antonio, Texas

Conditions: Sleep Disorders, Sleep Apnea, Sleep Disordered Breathing
Interventions: Polysomnography; Procedure
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Excessive Sleepiness
Interventions: armodafinil, placebo; Drug
Lead sponsor: Cephalon; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 427 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 4
States / cities: Atlanta, Georgia • Crestview, Kentucky • New York, New York + 1 more

Conditions: Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare, Nightmares, REM-Sleep Type, Nightmare Disorder With Associated Non-Sleep Disorder
Interventions: NightWare Therapeutic System; Device
Lead sponsor: NightWare; Industry
Eligibility: 22 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Posttraumatic Stress Disorder
Interventions: Cognitive Processing Therapy, Hypnosis; Behavioral
Lead sponsor: Center for Trauma Recovery, St Louis; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: PTSD Symptoms, Anxiety Symptoms, Depression Symptoms, Sleep Disturbance
Interventions: Clinician Supported PTSD Coach, Self Managed PTSD Coach; Behavioral
Lead sponsor: Florida International University; Other
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Insomnia
Interventions: Aspirin, Placebo; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 35 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Transient Insomnia
Interventions: Gabapentin, Placebo; Drug
Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 2,105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 23
States / cities: Mobile, Alabama • Phoenix, Arizona • Beverly Hills, California + 17 more

Conditions: Posttraumatic Stress Disorder, Insomnia Disorder
Interventions: Brief Behavioral Treatment for Insomnia (BBTI), Progressive Muscle Relaxation Training (PMRT); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Long COVID, Long COVID-19, Sleep Disturbance
Interventions: Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 469 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Restless Legs Syndrome (RLS)
Interventions: Injectafer, Placebo; Drug · Other
Lead sponsor: American Regent, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 19
States / cities: Mobile, Alabama • National City, California • Rancho Mirage, California + 15 more

Conditions: Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
Interventions: Positive Airway Pressure Device; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Primary Insomnia
Interventions: Acupuncture; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Sleep Quality, Fatigue
Interventions: Sleep Health Education; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 100 Years
Enrollment: 678 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Restless Legs Syndrome
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Sleep Initiation and Maintenance Disorders, Insomnia
Interventions: eplivanserin (SR46349), placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 608 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Bridgewater, New York

Conditions: Idiopathic Hypersomnia, Narcolepsy Without Cataplexy
Interventions: BTD-001, Placebo; Drug
Lead sponsor: Balance Therapeutics; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 23
States / cities: Birmingham, Alabama • Palo Alto, California • San Diego, California + 19 more

Conditions: Obstructive Sleep Apnea
Interventions: F&P Toffee Nasal and Toffee Nasal Pillows Masks; Device
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 22 Years and older
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Miami, Florida • St Louis, Missouri

Conditions: Gastroesophageal Reflux Disease
Interventions: Esomeprazole, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 45
States / cities: Huntsville, Alabama • Tucson, Arizona • Little Rock, Arkansas + 42 more

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Effects of Valerian on Sleep in Healthy Older Adults

Butrans for Treatment of Restless Legs Syndrome

The Clinical and Biochemical Effect of Therapeutic Massage on Fatigue and Insomnia in Women With Breast Cancer Receiving Radiation Therapy

Impact of Smoking Cessation on Sleep - 5

Validation of the ApneaLink Sleep Screener for Obstructive Sleep Apnea (OSA)

Prospective Evaluation of Heart Failure Patients With Central Sleep Apnea

Electrocardiography Data Analysis in Sleep Disorders

Study of the Effect of Armodafinil Treatment in Healthy Subjects With Excessive Sleepiness Associated With Jet Lag Disorder

Traumatic Nightmares Treated by NightWare (To Arouse Not Awaken)

Sleep-directed Hypnosis As A Complement To Cognitive Processing Therapy (CPT) In Treating Posttraumatic Stress Disorder (PTSD)

Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida

Preventing the Inflammatory Response to Experimentally-induced Insomnia Symptoms

A Study of the Safety of Gabapentin in a Potential Over-the-Counter Population With Occasional Sleeplessness

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

Acupuncture for the Treatment of Insomnia

The EMS Sleep Health Study: A Randomized Controlled Trial

Glutamate, Hyperarousal and Restless Legs Syndrome

Efficacy and Safety of Eplivanserin 5mg/Day on Sleep Maintenance Insomnia

A Study of Safety and Efficacy of BTD-001 in Treatment of Patients With Idiopathic Hypersomnia (IH) or Narcolepsy Type 2

Evaluation of the Toffee Nasal and Toffee Nasal Pillows Mask in Home, USA, 2022

Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US