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Conditions: Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
Interventions: Brenner FIT Standard, By Design Essentials, Dyad Plus; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 13 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Disruptive Behavior, Attention-deficit Hyperactivity, Oppositional Defiant Disorder
Interventions: Garmin; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 3 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Child Development
Interventions: Parenting group; Behavioral
Lead sponsor: Centers for Disease Control and Prevention; Federal
Eligibility: 18 Years and older
Enrollment: 547 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2013
U.S. locations: 2
States / cities: Los Angeles, California • Miami, Florida

Conditions: Parent-Child Relations, Meals, Autism Spectrum Disorder
Interventions: Parent-Mediated Intervention; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 2 Years to 7 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Disordered Eating Behaviors, Depression, Feeding Behaviors, Parent-Child Relations
Interventions: Parent Group Discussion; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: 12 Years and older
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Parent-Child Relations, Parenting, Adolescent Behavior, Communication
Interventions: Build and Support Your Teen's Strengths; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 13 Years to 15 Years
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, Dup15Q Syndrome, Duchenne Muscular Dystrophy, Phelan-McDermid Syndrome, Rett Syndrome, Smith Magenis Syndrome, Williams Syndrome, Turner Syndrome, Klinefelter Syndrome, Chromosome 22q11.2 Deletion Syndrome, Tuberous Sclerosis, Down Syndrome
Interventions: Parent-Infant Inter(X)action Intervention (PIXI); Behavioral
Lead sponsor: RTI International; Other
Eligibility: Up to 99 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Research Triangle Park, North Carolina

Conditions: Substance Use Disorders, Parent-Child Relations, Parent Child Abuse
Interventions: MIO-CPP, MIO-CPP-CRS; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Female only
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Parenting, Parent-Child Relations, Substance Use Disorders, Stress, Depression, Anxiety, Parenting Self-efficacy, Pediatrics
Interventions: Family Check-Up Online; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Not listed
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Sexual Behavior, Adolescent Behavior, Sexually Transmitted Diseases, Contraception Behavior, Parent-Child Relations
Interventions: Morehouse Family Health Study's Parent Toolkit 2.0, Morehouse Family Health Study's General Health Guide; Behavioral
Lead sponsor: Child Trends; Other
Eligibility: 12 Years to 15 Years
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Cairo, Georgia

Conditions: Interpersonal Relations
Interventions: SSGRIN-Parent Guide; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 8 Years to 12 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: Cary, North Carolina • Durham, North Carolina

Conditions: Parent-Child Relations, Parenting Self Efficacy, Child Mental Health
Interventions: Project Support, Case Management Services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 6 Years to 13 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Autism Spectrum Disorder, Disruptive Behavior, Externalizing Behavior, Parent-Child Interaction Therapy, Telehealth
Interventions: Tele-PCIT, Treatment as Usual; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 2 Years to 83 Months
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Violence, Non-accidental, Posttraumatic Stress Disorder, Parent-Child Relations, Assault, Youth
Interventions: Child and Family Traumatic Stress Intervention; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 8 Years to 18 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Bipolar Disorder (BD), Bipolar Disorder I or II, Bipolar Disorder Family Members, Screening Tool
Interventions: Co-design Workshop (Observational Procedure), Alpha Testing (Observational Procedure), Beta Testing (Observational Procedure), Youth Screening Pathway & Brief Follow-Up Interview (Observational Procedure); Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 7 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Abuse, Child, Crying, Parent-Child Relations
Interventions: Take 5 and Audio Clip, Take 5 Only; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Addiction, Substance Abuse Drug Chronic, Child Neglect, Child Neglect Emotional, Child Abuse, Parenting, Parent-Child Problem, Parent-Child Relations, Parent / Child Problem, Parenteral Drug Abuse, Parents
Interventions: Mothering From the Inside Out (MIO), Parent Education; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Parent-Child Relations, Parenting, Attachment Disorder
Interventions: Digital Game, Control; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 6 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Coral Gables, Florida • Miami, Florida

Conditions: Mental Health Issue, Parent-Child Relations
Interventions: LGBTQ-affirmative CBT, ABFT-SGM; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 20 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Adolescent, Psychopathology, Parent-Child Relations, Violence
Interventions: Promoting Positive Family Futures, Treatment as Usual; Behavioral
Lead sponsor: University of Notre Dame; Other
Eligibility: 12 Years to 75 Years
Enrollment: 900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Notre Dame, Indiana

Conditions: Parent-Child Relations, Child Maltreatment
Interventions: PriCARE/CARIÑO; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Months to 99 Years
Enrollment: 1,932 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Philadelphia, Pennsylvania

Conditions: Problem;Behaviour;Child, Parent-Child Relations
Interventions: Parent-Child Care; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 2 Years to 10 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Childhood Obesity, Obesity
Interventions: Mother with obesity, daughter with obesity, Mother with obesity, daughter without obesity, Mother without obesity, daughter with obesity, Mother without obesity, daughter without obesity, Mother with obesity, son with obesity, Mother with obesity, son without obesity, Mother without obesity, son with obesity, Mother without obesity, son without obesity, Father with obesity, daughter with obesity, Father with obesity, daughter without obesity, Father without obesity, daughter with obesity, Father without obesity, daughter without obesity, Father with obesity, son with obesity, Father with obesity, son without obesity, Father without obesity, son with obesity, Father without obesity, son without obesity; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 1,973 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Substance Abuse, Child Abuse
Interventions: Parenting Intervention; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2003
U.S. locations: 1
States / cities: New Haven, Connecticut

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Dyad Plus Effectiveness/Feasibility

Monitoring of Sleep and Behavior of Children 3-7 Years Old Receiving Parent-Child Interaction Therapy With the Help of Artificial Intelligence

Legacy for Children, an Early Intervention Study to Promote Optimal Child Development in Low-income Families

Parent-Mediated Intervention for Families With Children With Autism and Feeding Challenges

Conversations With Caregivers About Health and Appearance

A Pilot Efficacy and Implementation Study of the Strengths Intervention Project

Parent and Infant Inter(X)Action Intervention (PIXI)

MIO-CPP to Improve the Well-being, Permanency, and Safety Outcomes for Young Children at Risk of or in Out-of-home Placement in Philadelphia and Bucks Counties, and Affected by Maternal Substance Use

Parenting Young Children in Pediatrics

Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)

Parent Treatment for Child Social Adjustment

Examining Whether Project Support Works

Telehealth Rapid Intervention for Externalizing Behaviors in ASD

Addressing Traumatic Stress Symptoms in Children

FOCUS Bipolar: Families Opening Conversations for Understanding Signs

Take 5 + Audio Clip Randomized Control Trial

Stage III Community-based Efficacy Trial for Mothering From the Inside Out

Relationship Enhancement Digital Game

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

An Evidence-based Family Support Program for Parents and Children in Palestine: A Theory-based Intervention

Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)

Integrating Behavioral Treatment in Primary Care

Weight Stigma by Association in Parent-Child Dyads

Relational Parenting Group for Opioid-addicted Mothers