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ClinicalTrials.gov public records Last synced Jun 10, 2026, 5:41 PM EDT

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Showing 1–24 of 365 matching trials from the live ClinicalTrials.gov search.
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Recruiting Not applicable Interventional

Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors

NCT02896348
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
SynPhNe platform, Conventional therapy
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jun 10, 2026, 5:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Blood Flow Restriction Therapy Improve Strength for Shoulder External Rotators Better Than Exercise Alone

NCT03815760
View directory record Official record
Conditions
Muscular Weakness
Interventions
Blood Flow Restriction
Device
Lead sponsor
George Fox University
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional

Effects of Different Types of Augmented Feedback on Intrinsic Motivation and Spatiotemporal Gait Performance After Stroke

NCT04740060
View directory record Official record
Conditions
Stroke, Hemiparesis, Walking, Difficulty
Interventions
Augmented Feedback without Virtual Reality(VR, Augmented Feedback with Non-Game based VR, Augmented Feedback with Game based VR
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Not listed
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional Results available

Electromyography in Patients on Chronic Pyridostigmine Therapy

NCT02364180
View directory record Official record
Conditions
Muscle Weakness
Interventions
Electromyography (EMG)
Diagnostic Test
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
12 Years to 90 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Jun 10, 2026, 5:41 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Recovery of Physical Function After Critical Illness In Older Adults

NCT07225257
View directory record Official record
Conditions
Sepsis, Acute Lung Injury(ALI)
Interventions
Not listed
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jun 10, 2026, 5:41 PM EDT
Active, not recruiting Not applicable Interventional

Inspiratory Muscle Training Immediately After Lung Transplantation

NCT05309551
View directory record Official record
Conditions
Lung Transplantation, Chronic Lung Disease, Muscle Weakness, Rehabilitation
Interventions
IMT- Intervention group, IMT- Placebo group
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jun 10, 2026, 5:41 PM EDT
Not yet recruiting Not applicable Interventional

Spinal Stimulation and Gait Training to Improve Mobility in TBI

NCT06886152
View directory record Official record
Conditions
Traumatic Brain Injury, Traumatic Brain Injury (TBI), Hemiplegia and Hemiparesis
Interventions
Transcutaneous Spinal Cord Stimulation, Sham
Procedure · Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jun 10, 2026, 5:41 PM EDT
Terminated Phase 4 Interventional Results available

Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness?

NCT03382925
View directory record Official record
Conditions
Cervical Radiculopathy
Interventions
cervical interlaminar with lidocaine, cervical interlaminar with normal saline, Lidocaine, Triamcinolone Acetonide, Normal saline
Procedure · Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional

The Acute Effects of Passive Vibration on Cardiovascular Function in Individuals With Stroke

NCT01841840
View directory record Official record
Conditions
Stroke, Hemiparesis, Pre-Hypertension, Hypertension
Interventions
Low-Frequency Passive Vibration, High-Frequency Pasive Vibration
Other
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 28, 2013 · Synced Jun 10, 2026, 5:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hypertonia in Patients With Cerebral Palsy

NCT00123708
View directory record Official record
Conditions
Cerebral Palsy, Muscle Hypertonia
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
6 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

NCT02971072
View directory record Official record
Conditions
Acute Pain, Atrophic, Goals, Impairment, Infiltration, Injury, Muscle Weakness, Pain, Pathology, Shoulder Pain, Syndrome, Tendinopathy
Interventions
Subacromial injection, Physical Therapy
Procedure · Other
Lead sponsor
University of Oregon
Other
Eligibility
21 Years to 45 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional

A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial

NCT00715494
View directory record Official record
Conditions
Brain Injury, Muscle Weakness
Interventions
Cognitive, physical, and functional rehabilitation
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)

NCT03906656
View directory record Official record
Conditions
Pareses, Lower Extremity
Interventions
C-Brace, KAFO/SCO
Device
Lead sponsor
Otto Bock Healthcare Products GmbH
Industry
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
Sarasota, Florida • Chicago, Illinois • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Phase 2 Interventional

Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study)

NCT01895660
View directory record Official record
Conditions
Hemiparesis, Cerebral Palsy, Brain Injury
Interventions
Variations in Pediatric Constraint-Induced Movement Therapy (P-CIMT) versus usual and customary rehabilitation
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
2 Years to 9 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional

Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke

NCT03780296
View directory record Official record
Conditions
Chronic Stroke, Hemiplegia, Hemiparesis, Paralysis
Interventions
Real-time action observation with augmented Kinect
Device
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Canton, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Phase 2 Interventional Results available

Improving Stroke Rehabilitation: Spacing Effect and D-cycloserine

NCT00720759
View directory record Official record
Conditions
Stroke
Interventions
D-cycloserine + distributed treatment, D-cycloserine + condensed treatment, Placebo + distributed treatment, Placebo + condensed treatment
Drug · Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 6, 2014 · Synced Jun 10, 2026, 5:41 PM EDT
Suspended Not applicable Interventional

Improving Arm Function Using Wearable Exoskeletons

NCT05951491
View directory record Official record
Conditions
Hemiparesis; Poststroke/CVA
Interventions
Wearable Shoulder Exoskeleton, Wearable Hand Exoskeleton
Device
Lead sponsor
University of Idaho
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Phase 1Phase 2 Interventional Results available

The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke

NCT03080454
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke, Muscle Spasticity, Upper Extremity Paralysis
Interventions
sham Doublestim, anodal Doublestim
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Jun 10, 2026, 5:41 PM EDT
Recruiting Not applicable Interventional

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke

NCT03870672
View directory record Official record
Conditions
Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach, Sham rTMS approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jun 10, 2026, 5:41 PM EDT
Terminated Not applicable Interventional

Blood Flow Restriction Training in Rehabilitation Patients

NCT02174770
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
Interventions
Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Phase 4 Interventional

Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

NCT00018356
View directory record Official record
Conditions
Muscle Weakness, Muscular Atrophy
Interventions
exercise, testosterone
Procedure · Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
65 Years and older · Male only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2006
U.S. locations
1
States / cities
No. Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2011 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NM Balance Regulation With ULLS and Loss of Sleep

NCT05956964
View directory record Official record
Conditions
Muscle Weakness, Quadriceps Muscle Atrophy, Sleep Disturbance
Interventions
Sleep Restriction, Sleep Adequate
Behavioral
Lead sponsor
Lance Bollinger
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jun 10, 2026, 5:41 PM EDT
Completed Not applicable Interventional

Constraint Induced Movement Therapy Summer Camp

NCT02156713
View directory record Official record
Conditions
Cerebral Palsy, Cerebral Palsy, Diplegic, Infantile
Interventions
CIMT Camp
Behavioral
Lead sponsor
Kelly Tanner
Other
Eligibility
3 Years to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2015 · Synced Jun 10, 2026, 5:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
View directory record Official record
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jun 10, 2026, 5:41 PM EDT