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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Parturition Complication Clear all
Completed Not applicable Interventional

Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants

NCT04062851
View directory record Official record
Conditions
Gastric Residual Volume, Preterm Infant, Feeding Disorder Neonatal
Interventions
No Gastric residual volume monitoring
Other
Lead sponsor
AdventHealth
Other
Eligibility
2 Hours to 1 Month
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Phase 4 Interventional

NICU Antibiotics and Outcomes Trial

NCT03997266
View directory record Official record
Conditions
Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions
Ampicillin, Gentamycin, Normal saline
Drug
Lead sponsor
Michael Morowitz
Other
Eligibility
Up to 4 Hours
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
14
States / cities
Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 11, 2026, 10:25 PM EDT
Recruiting Phase 1 Interventional

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

NCT05065372
View directory record Official record
Conditions
Type 1 Diabetes, Diabetic Kidney Disease, Cardiovascular Diseases, Endothelial Dysfunction, Insulin Sensitivity
Interventions
Metformin Hcl 1000Mg Tab, Aminohippurate Sodium 20 % Injection, Iohexol 300 Mg/mL Injectable Solution, Placebo
Drug
Lead sponsor
Kalie Tommerdahl
Other
Eligibility
12 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 11, 2026, 10:25 PM EDT
Terminated Phase 4 Interventional

Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates

NCT00961753
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
optimized ibuprofen, Standard Ibuprofen
Drug
Lead sponsor
OSF Healthcare System
Other
Eligibility
1 Day to 29 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 27, 2014 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional

The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants

NCT03836430
View directory record Official record
Conditions
Postpartum Depression, Preterm Infant, Infant Development
Interventions
Newborn Behavioral Observation-Family Wellness (NBO-FW)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2022 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection

NCT01203345
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Sepsis
Interventions
IVIG, Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 72 Hours
Enrollment
2,416 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1988 – 1991
U.S. locations
8
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional

Noninferiority Trial of Liquid Human Milk Fortifier (HMF) Hydrolyzed Protein Versus Liquid HMF With Supplemental Liquid Protein

NCT03001479
View directory record Official record
Conditions
Human Milk, Premature Birth of Newborn
Interventions
Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid
Dietary Supplement
Lead sponsor
St. Louis University
Other
Eligibility
Up to 2 Weeks
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 11, 2026, 10:25 PM EDT
Not listed Not applicable Interventional

Umbilical Cord Care for the Prevention of Colonization

NCT01893060
View directory record Official record
Conditions
Line Insertion Site, Central Line-associated Bloodstream Infection (CLABSI)
Interventions
Povidone-Iodine, Chlorhexidine gluconate, Pluronic Cream, control
Drug · Other
Lead sponsor
University of Virginia
Other
Eligibility
Up to 7 Days
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Sep 11, 2026, 10:25 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Continuation of the nuMoM2b Heart Health Study

NCT05472597
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
RTI International
Other
Eligibility
18 Years and older · Female only
Enrollment
4,048 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
14
States / cities
Orange, California • Newark, Delaware • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional Results available

The Developmental Effects of NICU Positioning

NCT01628510
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Dandle Roo/Dandle Wrap, Traditional NICU Positioning
Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Hour to 7 Days
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 26, 2018 · Synced Sep 11, 2026, 10:25 PM EDT
Terminated Phase 4 Interventional

Metformin and Esomeprazole in Preterm Pre-eclampsia

NCT06359015
View directory record Official record
Conditions
Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions
Metformin, Esomeprazole
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling

NCT04859114
View directory record Official record
Conditions
Premature Birth
Interventions
Format of outcome data presentation, Displayed chance of survival
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,052 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Sep 11, 2026, 10:25 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Standards for the New Ballard Maturation Score

NCT01203449
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Pregnancy
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
1,090 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 1996
U.S. locations
11
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2015 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional

Timing of Inguinal Hernia Repair in Premature Infants

NCT01678638
View directory record Official record
Conditions
Inguinal Hernia, Premature Birth of Newborn
Interventions
IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 37 Weeks
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
40
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Sep 11, 2026, 10:25 PM EDT
Not listed No phase listed Observational

Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy

NCT01855347
View directory record Official record
Conditions
Infant, Premature, Diseases, Hypoxia, Necrotizing Enterocolitis
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Up to 3 Weeks
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2015 · Synced Sep 11, 2026, 10:25 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy

NCT06965530
View directory record Official record
Conditions
Pregnancy Related, Prematurity, Birth Outcome, Adverse
Interventions
Clinic-Based Medically Tailored Groceries (CB-MTG), Home Delivered Medically Tailored Groceries (HD-MTG), Home Delivered Medically Tailored Groceries plus Education (HD-MTG_PLUS)
Dietary Supplement
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 11, 2026, 10:25 PM EDT
Completed No phase listed Observational

Nasogastric/Orogastric Tube Placement Confirmation in Neonates Utilizing Self-contained pH Device, a Feasibility Study

NCT06274944
View directory record Official record
Conditions
Premature Birth
Interventions
nasogastric tube placement pH confirmation device
Device
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 2 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 11, 2026, 10:25 PM EDT
Active, not recruiting Phase 3 Interventional Results available

Management of the PDA Trial

NCT03456336
View directory record Official record
Conditions
Infant, Premature, Patent Ductus Arteriosus, Infant, Newborn, Diseases, Patent Ductus Arteriosus After Premature Birth
Interventions
Active Treatment, Expectant Management
Other
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
48 Hours to 21 Days
Enrollment
482 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 11, 2026, 10:25 PM EDT
Terminated No phase listed Observational

Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants

NCT01062828
View directory record Official record
Conditions
Premature Newborn, Necrotizing Enterocolitis
Interventions
Citrulline samples
Diagnostic Test
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 27, 2017 · Synced Sep 11, 2026, 10:25 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Protein and Ultrasound Indicators of Preterm Birth

NCT01412931
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Sep 11, 2026, 10:25 PM EDT
Not listed Not applicable Interventional

Frozen Blastocyst Transfer Using Conventional Timing Versus Timing by Endometrial Receptivity Analysis

NCT03558399
View directory record Official record
Conditions
Implantation Failure, Infertility, Female
Interventions
FET according to ERA, FET according to standard protocol
Other
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
30 Years to 40 Years · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional

Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants

NCT02475434
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Cream Supplement group
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 14 Days
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
7
States / cities
Orlando, Florida • East Lansing, Michigan • Boardman, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 11, 2026, 10:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Integrated Population (I-POP) Health Trial

NCT04761016
View directory record Official record
Conditions
Diabetes, Hypertension, Chronic Kidney Diseases, Obesity, Chronic Disease
Interventions
Usual Care, I-POP + CHW navigation
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 11, 2026, 10:25 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Mifepristone Induction for Fetal Demise

NCT02620904
View directory record Official record
Conditions
Intrauterine Fetal Demise, Fetal Death
Interventions
Mifepristone, placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Sep 11, 2026, 10:25 PM EDT