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ClinicalTrials.gov public records Last synced Sep 7, 2026, 2:34 PM EDT

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Showing 1–24 of 67 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Patellofemoral Disorder Clear all
Not listed No phase listed Observational

Survivorship and Outcomes of Robotically Assisted Patellofemoral UKA

NCT01947686
View directory record Official record
Conditions
Patellofemoral Knee Arthroplasty
Interventions
Robotically guided patellofemoral UKA isolated patellofemoral implants
Device
Lead sponsor
St. Helena Hospital Coon Joint Replacement Institute
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
2
States / cities
St. Helena, California • Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Sep 7, 2026, 2:34 PM EDT
Not listed Not applicable Interventional

Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain

NCT06565520
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
transcranial direct current stimulator
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Trial of Self-managed Approaches for Patellofemoral Pain Syndrome in Active Duty

NCT02597673
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Home Exercise Program (HEP), NMES, TENS
Other · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional

The Evaluation of a Novel Treatment Algorithm for Patients With Patellofemoral Syndrome

NCT01767246
View directory record Official record
Conditions
Patellofemoral Syndrome
Interventions
PFS Algorithm treatment, Multimodal treatment
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Columbus, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 6, 2015 · Synced Sep 7, 2026, 2:34 PM EDT
Recruiting No phase listed Observational

Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms

NCT07472088
View directory record Official record
Conditions
Knee Osteoarthritis, Patellofemoral Pain (PFPS)
Interventions
WBCT
Radiation
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Active, not recruiting No phase listed Observational

The Impact of Tibial Tubercle-trochlear Groove Distance and Patellar Height on the Outcome of Isolated Medial Patellofemoral Ligament Reconstruction

NCT03076008
View directory record Official record
Conditions
Patellar Dislocation
Interventions
Observational
Other
Lead sponsor
University of Minnesota
Other
Eligibility
13 Years to 90 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of the Efficacy of Synvisc-One® for the Treatment of Patellofemoral Chondromalacia

NCT01771952
View directory record Official record
Conditions
Chondromalacia Patella, Patellofemoral Pain Syndrome
Interventions
Synvisc-One™, Sham Treatment
Device · Other
Lead sponsor
University of Virginia
Other
Eligibility
15 Years to 45 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Mindful Miles Pilot Feasibility Study

NCT07462429
View directory record Official record
Conditions
Patellofemoral Pain, PFP, Patellofemoral Pain Syndrome, Patellofemoral Pain, Patellofemoral Pain (PFPS)
Interventions
Progressive Mindful Physical Activity
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Recruiting Phase 3 Interventional

Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome

NCT03184545
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
EMS, Physical therapy
Device · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 40 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Lumbopelvic Manipulation on Hip and Knee Neuromuscular Activity

NCT01637480
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Lumbopelvic manipulation
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional

The Effect of Psychologically Informed Education in Adolescents With Patellofemoral Pain

NCT03897907
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Psychologically Informed Education Video, Anatomy Education Video
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Comparison Study of Two Chiropractic Treatment Protocols for Knee Pain Due to Patellofemoral Pain Syndrome

NCT00401050
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
chiropractic manipulative therapy, knee exercises, Graston Instrument Soft Tissue Mobilization (GISTM)
Procedure
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2010 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Hip Activation Compared to Hip Plus Balance Training on the Forward-Step-Down Test

NCT06298903
View directory record Official record
Conditions
Control of Frontal Plane Biomechanics, Patellofemoral Pain Syndrome
Interventions
Hip Activation, Hip activation + Single leg balance
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 7, 2026, 2:34 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Bilateral Knee Pain and Dry Needling

NCT05976269
View directory record Official record
Conditions
Patellofemoral Pain
Interventions
Dry needling
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Recruiting Not applicable Interventional

Emovi 3D Knee Assessment Device Intervention for Operational Readiness

NCT06517056
View directory record Official record
Conditions
Patellofemoral Pain, Patellofemoral Pain Syndrome
Interventions
Emovi Knee Kinesiography
Device
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Honolulu, Hawaii • Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 7, 2026, 2:34 PM EDT
Active, not recruiting Not applicable Interventional

Strength or Power Training for Patellofemoral Pain

NCT05403944
View directory record Official record
Conditions
Patellofemoral Pain
Interventions
Standard of Care Rehabilitation (SOC), Strength Training Rehabilitation Incorporating Power Exercises (STRIPE)
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 40 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Storrs, Connecticut • Orlando, Florida • Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

NCT00445224
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Hip Progressive Resistive Exercise, Quad Progressive Resistive Exercises
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
15 Years to 35 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Sep 7, 2026, 2:34 PM EDT
Withdrawn Not applicable Interventional

BFR After Biceps Tendon Repair and MPFLR

NCT05375071
View directory record Official record
Conditions
Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions
Blood Flow Restriction (BFR) Therapy, Physical Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 7, 2026, 2:34 PM EDT
Completed No phase listed Observational

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

NCT01862731
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Terminated Not applicable Interventional

Repair of Medial Patellofemoral Ligament Compared to Conservative Treatment for First Time Patella Dislocation

NCT02185001
View directory record Official record
Conditions
Dislocated Patella, Torn Medial Patellofemoral Ligament
Interventions
Direct Medial Patellofemoral Ligament (MPFL) Repair, Physical therapy
Procedure
Lead sponsor
Orthopedic Specialty Institute
Industry
Eligibility
10 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Coeur d'Alene, Idaho
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Sep 7, 2026, 2:34 PM EDT
Active, not recruiting Not applicable Interventional

Persona Ti-Nidium Post-Market Clinical Follow-up

NCT04817969
View directory record Official record
Conditions
Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
Interventions
Zimmer Biomet Persona Ti-Nidium Total Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2034
U.S. locations
7
States / cities
Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 7, 2026, 2:34 PM EDT
Withdrawn Not applicable Interventional

Patient Self Monitoring of Physical Therapy Exercise

NCT01781325
View directory record Official record
Conditions
Patellofemoral Syndrome
Interventions
IBEHR
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 7, 2026, 2:34 PM EDT
Not listed No phase listed Observational

Survivorship and Outcomes of Robotic-Arm Assisted Bicompartmental Arthroplasty

NCT03668704
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
St. Helena Hospital Coon Joint Replacement Institute
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
St. Helena, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Sep 7, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Psychologically Informed Education Intervention for Adolescents With Atraumatic Lower-Extremity Injuries

NCT05701618
View directory record Official record
Conditions
Leg Injury
Interventions
Psychologically Informed Education Video Series, Anatomy and biomedical education videos
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 7, 2026, 2:34 PM EDT