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ClinicalTrials.gov public records Last synced Sep 23, 2026, 4:39 AM EDT

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Showing 1–24 of 3,943 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pathophysiology Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

KNA Proof-of-Concept

NCT04968041
View directory record Official record
Conditions
Adherence, Treatment, Retention, Cognitive Impairment, Mild
Interventions
Motivational Interviewing-Cognitive Behavioral Therapy Ketogenic Nutrition Adherence Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
60 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Sep 23, 2026, 4:39 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Circulating Biomarkers in the Development of Type 1 Diabetes

NCT05505669
View directory record Official record
Conditions
Diabetes
Interventions
One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit.
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
Not listed
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 23, 2026, 4:39 AM EDT
Completed No phase listed Observational

Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid

NCT05611905
View directory record Official record
Conditions
Renal Excretion, Bacterial Infections, Inflammatory Disease, Oncologic Disease
Interventions
11C-para-aminobenzoic acid PET/CT, Probenecid
Combination Product · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Not applicable Interventional

Treating Cancer-Related Fatigue Through Systematic Light Exposure

NCT01873794
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplantation, Breast Cancer, Fatigue, Mild Cognitive Impairment, Light, Quality of Life, Sleep
Interventions
Bright white light, Dim red light
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Hackensack, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Model System for Transient Forearm Blood Vessel Dysfunction

NCT00453531
View directory record Official record
Conditions
Limb Ischemia, Ischemic Preconditioning
Interventions
Limb Ischemia, Acetylcholine
Procedure · Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 45 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Not applicable Interventional

Stroke Study: Operative Strategies to Reduce Cerebral Embolic Events During Coronary Artery Bypass Surgery

NCT01502683
View directory record Official record
Conditions
Stroke
Interventions
No aortic clamping, partial occluding clamp, single cross clamp, cross clamp and partial occluding clamp
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 23, 2026, 4:39 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Void Trials After Two Voiding Trials (TVT)

NCT03937531
View directory record Official record
Conditions
Postoperative Voiding Dysfunction, Postoperative Urinary Retention
Interventions
Bladder Scanner
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Sep 23, 2026, 4:39 AM EDT
Active, not recruiting Phase 4 Interventional

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

NCT03581877
View directory record Official record
Conditions
Pulmonary Embolism, Pulmonary Hypertension, Thromboembolism, Right Ventricular Dysfunction
Interventions
Alteplase, EKOS
Drug · Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Bay Shore, New York • Queens, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Not applicable Interventional

The Combined Aerobic Exercise and Cognitive Training (ACT) Trial: The ACT Trial

NCT03313895
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Aerobic & Cognitive Training (ACT), Cycling Only, Cognitive Training Only, Stretching and Mental Stimulating Activities
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
65 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Phoenix, Arizona • Stanford, California • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Phase 1 Interventional

Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors

NCT00594633
View directory record Official record
Conditions
Brain Tumor, Brain Cancer, Cns Cancer, Cognitive Dysfunction
Interventions
donepezil and questionaires
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Phase 2 Interventional Results available

A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease

NCT05063539
View directory record Official record
Conditions
Alzheimer Disease
Interventions
LY3372689, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
60 Years to 85 Years
Enrollment
327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
35
States / cities
Canoga Park, California • Fresno, California • Irvine, California + 30 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Phase 3 Interventional Results available

Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

NCT01853553
View directory record Official record
Conditions
ADPKD
Interventions
Spironolactone, Sugar pill
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 55 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 23, 2026, 4:39 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Speech, Linguistic and Acoustic Markers in Parkinson's Disease

NCT04273672
View directory record Official record
Conditions
Parkinson Disease, Cognitive Impairment, Mild, Speech
Interventions
Cognitive Battery, Voice, Speech and Language Analysis, Questionnaires and Clinical Assessments, DNA Analysis
Diagnostic Test · Behavioral · Genetic
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Phase 2 Interventional

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

NCT01854294
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
GM604, Placebo comparator
Drug
Lead sponsor
Genervon Biopharmaceuticals, LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 23, 2026, 4:39 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Implications of Amyloid Pathology

NCT00900770
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 28, 2009 · Synced Sep 23, 2026, 4:39 AM EDT
Completed No phase listed Observational

Dyskinesia, Heterotaxy and Congenital Heart Disease

NCT00608556
View directory record Official record
Conditions
Ciliary Dyskinesia, Primary, Kartagener Syndrome, Congenital Heart Defects, Situs Inversus
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
2 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 23, 2026, 4:39 AM EDT
Recruiting Not applicable Interventional

Prostate Stimulation for Sexual Dysfunction

NCT05468931
View directory record Official record
Conditions
Sexual Dysfunction, Erectile Dysfunction, Delayed Ejaculation, Anorgasmia
Interventions
Prostate stimulator
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 23, 2026, 4:39 AM EDT
Recruiting Not applicable Interventional

Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's

NCT05748613
View directory record Official record
Conditions
Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
Interventions
Computerized Anxiety Sensitivity Treatment, Health Education Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
60 Years and older
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Tallahassee, Florida • Athens, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 23, 2026, 4:39 AM EDT
Not listed No phase listed Observational

Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation.

NCT03701997
View directory record Official record
Conditions
Ventricular Dysfunction, Ventricular Dysfunction, Left, Ventricular Dysfunction, Right
Interventions
EXCOR Pediatric
Device
Lead sponsor
Berlin Heart, Inc
Industry
Eligibility
1 Day to 21 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Sep 23, 2026, 4:39 AM EDT
Not yet recruiting Phase 2 Interventional

Targeting Interferon Gamma With Emapalumab to Lung Transplant Recipients With Interferon Gamma-high Acute Lung Allograft Dysfunction

NCT07538336
View directory record Official record
Conditions
Lung Transplant
Interventions
Emapalumab, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 23, 2026, 4:39 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Transgender Post-reassignment Urogynecologic Measures and Perceptions

NCT03293771
View directory record Official record
Conditions
Gender Identity Disorder of Adult, Voiding Disorders, Sexual Dysfunction
Interventions
Focus group interviews, Questionnaire packet
Other · Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Modulation of Micro-RNA Pathways by Gemfibrozil in Predementia Alzheimer Disease

NCT02045056
View directory record Official record
Conditions
Preclinical Alzheimer's Disease
Interventions
Gemfibrozil, Placebo
Drug
Lead sponsor
Gregory Jicha, 323-5550
Other
Eligibility
65 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Phase 1 Interventional

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT05395481
View directory record Official record
Conditions
Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
Interventions
LY3849891, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 70 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
13
States / cities
Chandler, Arizona • Orange, California • Rialto, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 23, 2026, 4:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Peripheral Neuromodulation on Vaginal Blood Flow - Study 2

NCT06999265
View directory record Official record
Conditions
Female Sexual Dysfunction, Female Sexual Dysfunction Due to Physical Condition
Interventions
Transcutaneous electrical nerve stimulation - Tibial Nerve, Transcutaneous electrical nerve stimulation - Genital Nerve, Neutral and Erotic Film Clip Alternation
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 23, 2026, 4:39 AM EDT