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ClinicalTrials.gov public records Last synced Nov 10, 2026, 9:54 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2449–2472 of 3,983 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Aging
Interventions: Computerized Plasticity-Based Adaptive Cognitive Training, Educational DVDs; Other
Lead sponsor: Posit Science Corporation; Industry
Eligibility: 65 Years and older
Enrollment: 487 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Aging, Mortality, All-cause Mortality, Life Expectancy, Cardiovascular Diseases, Neoplasms, Cognitive Dysfunction, Metabolic Syndrome, Frailty, Musculoskeletal Disease, Neurodegenerative Disease, Dementia, Activities of Daily Living, Health Related Quality of Life, Environmental Exposure, Occupational Diseases, Health Equity, Social Determinants of Health, Physical Disability
Interventions: Multi-Domain Ecological and Clinical Data Linkage; Other
Lead sponsor: Longevity Metrics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,000,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2099
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Mild Cognitive Impairment
Interventions: sham tDCS, active tDCS; Device
Lead sponsor: University of Michigan; Other
Eligibility: 60 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Anxiety, Depression, Sleep Quality, Cognitive Impairment
Interventions: Low Dose MMFS-205-SR, High Dose MMFS-205-SR, Placebo; Dietary Supplement
Lead sponsor: Neurocentria, Inc.; Industry
Eligibility: 60 Years to 85 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Springfield, Missouri

Conditions: Hypoglycemia
Interventions: Glucose clamp; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 55 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
Interventions: Elator; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Obstructive Pulmonary Disease, Diastolic Dysfunction
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2021
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: Cromolyn Sodium, Cetirizine Hydrochloride; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 21 Years to 80 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Hypertension, Aging, Endothelial Dysfunction, Men
Interventions: Blueberry Powder, Placebo Powder; Dietary Supplement
Lead sponsor: Colorado State University; Other
Eligibility: 40 Years to 75 Years · Male only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Mild Cognitive Impairment, Herpes Simplex 1, Herpes Simplex 2
Interventions: Valacyclovir hydrochloride 500mg caplet, Placebo sugar pill caplet; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 50 Years to 95 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Prostate Cancer, Prostatectomy, Erectile Dysfunction Following Radical Prostatectomy, Incontinence, Urinary
Interventions: BioDFence G3; Biological
Lead sponsor: AdventHealth; Other
Eligibility: 40 Years to 70 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Celebration, Florida

Conditions: Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis
Interventions: Survodutide, Placebo; Combination Product
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 18 Years and older
Enrollment: 1,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2031
U.S. locations: 165
States / cities: Birmingham, Alabama • Peoria, Arizona • Scottsdale, Arizona + 132 more

Conditions: Pediatric Obesity, Insulin Resistance, Mitochondrial Dysfunction
Interventions: Exercise, Lifestyle counseling; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 10 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Brain Injuries, Traumatic, Neurocognitive Disorders, Brain Injuries
Interventions: Tolcapone; Drug
Lead sponsor: Sheppard Pratt Health System; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression, Medication Administered in Error, Cognitive Impairment
Interventions: Not listed
Lead sponsor: University of Rochester; Other
Eligibility: 65 Years and older
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Functional Gastrointestinal Disorders (FGIDs), Cyclic Vomiting Syndrome, Functional Dyspepsia, Dysautonomia
Interventions: Percutaneous electrical nerve field stimulation, Hypnotherapy; Device · Behavioral
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 11 Years to 18 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Nonalcoholic Steatohepatitis (NASH), Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: Miricorilant; Drug
Lead sponsor: Corcept Therapeutics; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Asymptomatic Left Ventricular Systolic Dysfunction (Disorder), Heart Failure
Interventions: AI-enabled ECG-based Screening Tool; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Erectile Dysfunction
Interventions: Shockwave therapy, Sham shockwave therapy; Device · Other
Lead sponsor: University of Miami; Other
Eligibility: 30 Years to 70 Years · Male only
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: MTBI - Mild Traumatic Brain Injury, Dysfunction of Vestibular System
Interventions: Conventional Therapy (CPT), CAREN Therapy, Augmented Reality (AR) Therapy; Other · Device
Lead sponsor: Naval Health Research Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 3
States / cities: San Diego, California • Bethesda, Maryland

Conditions: Mild Cognitive Impairment
Interventions: External Counterpulsation (EECP); Device
Lead sponsor: Patrick Moriarty, MD, FACP, FACC; Other
Eligibility: 18 Years to 85 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Cognitive Decline, Focus Deficit
Interventions: Auri Super Mushroom Daily Gummies; Dietary Supplement
Lead sponsor: Auri Nutrition; Industry
Eligibility: 30 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Cognitive Decline, Chemo-brain
Interventions: Memantine; Drug
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: SI Joint Pain
Interventions: 0.75% bupivacaine, .75% bupivacaine; Drug
Lead sponsor: SI-BONE, Inc.; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 7
States / cities: Mount Vernon, Illinois • Lexington, Kentucky • Cleveland, Ohio + 4 more

Search by objective public record fields.

Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)

Human Observatory Study

Multimodal Investigation of Neural Plasticity

Comparison of MMFS Dosages in Older Adults

Differing Levels of Hypoglycemia

Use of an External Erectile Device in Transgender Man Following Phalloplasty

Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of COPD

Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction

Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women

Valacyclovir for Mild Cognitive Impairment

BioDFence® G3 For Full Nerve-Sparing Robotic-Assisted Radical Prostatectomy

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Intensive Exercise to Improve Mitochondrial Dysfunction in Pediatric Obesity

Evaluate the Effects of Tolcapone on Cognitive and Behavioral Dysfunction in Patients With BI and NCD

Screening and Interventions in an Acute Care Setting

Autonomic Reactivity and Personalized Neurostimulation

Evaluating the Pharmacokinetics and Safety of Miricorilant

ECG AI-Guided Screening for Low Ejection Fraction

Low Intensity Shockwaves Therapy for the Treatment of Erectile Dysfunction. 12- Month Follow-Up

Use of Virtual and Augmented Reality Devices in Vestibular Physical Therapy for mTBI

Enhanced External Counterpulsation and Its Effects on Vascular Hemodynamics in Cognitively Impaired Patients

Effects of Auri Super Mushroom Daily Gummies on Cognitive Health

Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer

Validity and Reliability of Diagnostic Findings of SI Joint Blocking