Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 8, 2026, 3:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 457–480 of 3,978 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Cognition Disorders
Interventions: Cardiopulmonary bypass machine; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 273 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 4
States / cities: Atlanta, Georgia • Durham, North Carolina • Philadelphia, Pennsylvania + 1 more

Conditions: Cognitive Impairment
Interventions: MRI, Ketamine; Other · Drug
Lead sponsor: Yale University; Other
Eligibility: 16 Years to 60 Years
Enrollment: 143 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Depression
Interventions: Escitalopram; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 60 Years to 90 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2015
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Memory Impairment, Sleep Disorder
Interventions: Transdiagnostic sleep and circadian intervention (TranS-C); Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 60 Years and older
Enrollment: 119 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: Ivacaftor, standard of care treatment; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Breast Carcinoma, Carcinoma of Unknown Primary, Endometrial Carcinoma, Esophageal Carcinoma, Liver Failure, Lung Carcinoma, Malignant Head and Neck Neoplasm, Malignant Testicular Neoplasm, Melanoma, Metastatic Malignant Solid Neoplasm, Ovarian Carcinoma, Renal Failure, Unresectable Malignant Neoplasm, Urothelial Carcinoma
Interventions: Carboplatin, Laboratory Biomarker Analysis, Paclitaxel, Pharmacological Study, Veliparib; Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2027
U.S. locations: 17
States / cities: Duarte, California • Sacramento, California • South Pasadena, California + 13 more

Conditions: Schizophrenia, Cognitive Impairment
Interventions: ALTO-101, ALTO-101 Transdermal Delivery System, Placebo, Placebo Transdermal Delivery System; Drug · Device
Lead sponsor: Alto Neuroscience; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 14
States / cities: Garden Grove, California • Los Angeles, California • Orange, California + 9 more

Conditions: Cardiotoxicity, Cancer, Cardiac Arrhythmia, Left Ventricular Dysfunction, Breast Cancer, Multiple Myeloma
Interventions: Mobile Cardiac Telemetry, Wearable Cardiac Monitor; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Depression, Intracranial Atherosclerosis, Coronary Artery Disease
Interventions: Not listed
Lead sponsor: Yale University; Other
Eligibility: 40 Years and older
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 2
States / cities: New Haven, Connecticut • Baltimore, Maryland

Conditions: Paralysis; Quadriplegic, Quadraplegia, Tetraplegia, Tetraplegic Motor Dysfunction Following Brainstem or Spinal Cord Injury, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis (ALS), Brainstem Stroke, Paralysis, Brain-computer Interface, BCI
Interventions: Mind Extender (MindEx); Device
Lead sponsor: Nader Pouratian; Other
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Leiomyoma, Incontinence, Prolapse
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Activities of Daily Living, Accidental Fall, Sarcopenia, Arteriosclerosis, Diabetes Mellitus, Type 2, Hypertension, Cognitive Decline, Executive Function, Cognitive Aging
Interventions: Socially-Based Exercise Intervention for Older Adults; Behavioral
Lead sponsor: Western Kentucky University; Other
Eligibility: 60 Years to 85 Years
Enrollment: 241 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 4
States / cities: Dixon, Kentucky • Henderson, Tennessee • Johnson City, Tennessee + 1 more

Conditions: Breathing, Mouth, Lung Function Decreased, Vocal Cord Dysfunction, Laryngeal Obstruction, Asthma
Interventions: Impulse Oscillometer; Device
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
Interventions: Active Brains 1, Active Brains 2; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 60 Years and older
Enrollment: 267 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Liver Transplant Recipients
Interventions: Cozaar; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 62 participants
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Breast Cancer
Interventions: 3 month physical activity intervention; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 30 Years to 70 Years · Female only
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Breast Cancer
Interventions: Not listed
Lead sponsor: Kettering Health Network; Other
Eligibility: 18 Years to 65 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Dayton, Ohio • Kettering, Ohio

Conditions: Sexual Dysfunction, Breast Cancer, Prostate Cancer
Interventions: Sensate Focus exercise; Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Providence, Rhode Island

Conditions: Obesity, Insulin Resistance
Interventions: Glucosamine Hydrochloride; Drug
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 21 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Sepsis
Interventions: GFR by Iohexol, Urine Collection, Blood samples; Diagnostic Test
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Cerebral Palsy
Interventions: pneuRIP; Device
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 5 Years to 17 Years
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Alcohol Drinking, Chronic Inflammation, Neurocognitive Dysfunction, Liver Diseases, HIV Infections
Interventions: Contingency Management (CM); Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 75 Years
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Cognitive Decline, Cognitive Dysfunction
Interventions: Polyphenol Supplement, Placebo Supplement; Dietary Supplement
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cognitive Impairment
Interventions: Neurocognitive function assessment; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 60 Years and older
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Nashville, Tennessee

Search by objective public record fields.

Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest

Characterizing Clinical and Pharmacological Neuroimaging Biomarkers

Treatment Response of Geriatric Depression

Improving Patient Memory for Treatment for Mild Cognitive Impairment

Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Study of ALTO-101 in Patients With Schizophrenia

Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)

Intracranial Atherosclerosis and Depression After Coronary Artery Bypass Graft

MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System

Uterine Artery Embolization and Pelvic Floor Symptoms

Bingocize: A Novel Mobile Application for Older Adult Health

Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma

Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain

The Effects of Angiotensin II Receptor Blockade on Kidney Function and Scarring After Liver Transplant

Physical Activity, Fatigue, Sleep, and Inflammation

Magnetic Resonance Imaging (MRI) of Tumor Response and Cognitive Impairment in Breast Cancer Patients Undergoing Chemotherapy

An Intimacy Intervention for Couples Completing Breast or Prostate Cancer

Effects of Oral Glucosamine on Insulin and Blood Vessel Activity in Normal and Obese People

Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS

Non-Invasive Measurement of Pulmonary Dysfunction in Children With Cerebral Palsy

30-to-90 Day Challenge: Effects of Alcohol Cessation on Health Outcomes

Polyphenols and Cognitive Decline

Assessment of Cognitive and Functional Impairment in Older Patients After ERCP