Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 8, 2026, 6:14 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 3,978 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Breast Cancer, Sarcoma, Gastric (Stomach) Cancer, Lung Cancer, Head and Neck Cancer, Colorectal Cancer, Ovarian Cancer, Liver Cancer, Genitourinary Cancer, Gynecologic Cancer
Interventions: Riluzole, Placebo; Drug · Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Orange, California

Conditions: Eustachian Tube Dysfunction
Interventions: EarPopper, Tympanometry, Tubomanometry; Device
Lead sponsor: Cuneyt M. Alper; Other
Eligibility: 5 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Traumatic Brain Injury
Interventions: inhaled nitric oxide; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cardiomyopathy, Hypertrophic
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: POTS, POTS - Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Autonomic Dysfunction
Interventions: Blood Sample Collection; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Cancer, Chemotherapy-Related Cognitive Impairment
Interventions: Individualized Piano Keyboard Instruction; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 65 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Stroke
Interventions: hyaluronidase plus saline, saline; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Erectile Dysfunction
Interventions: Sildenafil Cream, Placebo Cream, Penile Plethysmography (RigiScan); Drug · Device
Lead sponsor: Strategic Science & Technologies, LLC; Industry
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 3
States / cities: San Diego, California • New Orleans, Louisiana • New York, New York

Conditions: Diabetes Mellitus, Type 2, Insulin Response, Endothelial Dysfunction
Interventions: Tauroursodeoxycholic acid; Dietary Supplement
Lead sponsor: Boston University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Late Life Depression, Cognitive Decline, Depressive Disorder, Treatment-Resistant, Levodopa, Gait Impairment
Interventions: L-Dopa, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 60 Years and older
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania • Nashville, Tennessee

Conditions: Aging, Mild Cognitive Impairment, Hypertension
Interventions: bpMedManage; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 60 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Tucson, Arizona • Champaign, Illinois

Conditions: Alcohol Drinking, Alcohol-Related Disorders, Disease, Inflammation, Alcoholism, Cognitive Dysfunction, Pathologic Processes, Drinking Behavior, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder, Cognition Disorder, Neurocognitive Disorders, Minocycline, Anti-Bacterial Agents, Anti-Infective Agents
Interventions: Minocycline, Sugar pill; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 25 Years to 65 Years
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Catonsville, Maryland

Conditions: Endothelial Dysfunction
Interventions: Creatine Monohydrate, Maltodextrin (Placebo); Other
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Cognitive Decline, Cognitive Dysfunction, Brain Health, Post CoV-2 Syndrome, COVID Long-Haul
Interventions: Cognivue; Device
Lead sponsor: Cognivue, Inc.; Industry
Eligibility: 18 Years to 95 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 4
States / cities: Irvine, California • Visalia, California • Boca Raton, Florida + 1 more

Conditions: Erectile Dysfunction
Interventions: CaverStem; Procedure
Lead sponsor: Creative Medical Health, Inc.; Industry
Eligibility: 18 Years to 85 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Torrance, California

Conditions: Heart Failure, Cognition Disorders
Interventions: Not listed
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Cognitive Dysfunction
Interventions: N-acetylcysteine and ketamine, placebo and ketamine; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Patent Foramen Ovale, Cardiac Implantable Electronic Device
Interventions: Apixaban, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
Interventions: Not listed
Lead sponsor: Arbor Research Collaborative for Health; Other
Eligibility: Up to 18 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2029
U.S. locations: 15
States / cities: Los Angeles, California • San Francisco, California • Aurora, Colorado + 12 more

Conditions: Aging, Fragility, Endothelial Dysfunction
Interventions: Ischemic Conditioning; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 65 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Wauwatosa, Wisconsin

Conditions: Alzheimer Disease or Associated Disorder, Dementia, Cognitive Decline
Interventions: Door-through-door companion rideshare, Curb-to-curb rideshare services; Other
Lead sponsor: Onward Health, Inc; Industry
Eligibility: 60 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Leandro, California

Conditions: Diabetic Retinopathy
Interventions: Ketorolac 0.45% ophthalmic solution, Placebo - Preservative-free artificial tears, Aqueous PGE2 and inflammatory cytokines measurements; Drug · Other
Lead sponsor: Stephen J. Kim, MD; Other
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Functional Impairment, Cognitive Impairment
Interventions: iHI-FIVES; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 1,406 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Heart Failure
Interventions: Rheos® system; Device
Lead sponsor: CVRx, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2021
U.S. locations: 22
States / cities: Mobile, Alabama • Inglewood, California • Los Angeles, California + 18 more

Search by objective public record fields.

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

Tubomanometry and EarPopper Devices for Eustachian Tube Function Testing

Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury

The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19

Individualized Piano Instruction (IPI) for Improving Cognition in Breast Cancer Survivors.

Myofascial Dysfunction in Post Stroke Shoulder Pain

Phase 2a Topical Sildenafil Proof-of-Concept Study in Men With Mild to Moderate ED

Effects of TUDCA on Endothelial Function in Type 2 DM

Dopaminergic Dysfunction in Late-Life Depression

bpMedManage: Digital Technology to Support Adherence to Hypertension Medications

Neuroimmune Dysfunction in Alcohol Use Disorder

The Effect of NADPH Oxidase and Creatine Supplementation on Microvascular Blood Flow Regulation

Open-label, Post-marketing, Prospective Study to Assess Impact of COVID-19 on Cognitive Function in Patients

Autologous Bone Marrow Concentrate in Treatment of Erectile Dysfunction.

Cognitive Problems in Veterans With Heart Failure

N-acetylcysteine and NMDA Antagonist Interactions

Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical Emboli

Longitudinal Study of Mitochondrial Hepatopathies

Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals

Door-Through-Door Companion Rideshare Technology for Individuals With Alzheimer's Disease and Related Dementias (AD/ADRD)

INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study

Optimizing Function and Independence Through iHI-FIVES

Rheos System for the Treatment of HFpEF Heart Failure