Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 1:59 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 135 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Patients Undergoing Cardiac Surgery Clear all

Conditions: Cardiovascular Disease
Interventions: Hemolink (hemoglobin raffimer IV solution); Drug
Lead sponsor: Hemosol; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 19
States / cities: San Francisco, California • Stanford, California • Sarasota, Florida + 14 more

Conditions: Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury, Myocardial Revascularization
Interventions: (MC-1) Pyridoxal-5'-phosphate; Drug
Lead sponsor: Medicure; Industry
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cardiorespiratory; Insufficiency, Due to A Procedure, Long-Term, Cardiac Surgery
Interventions: Cardiac Exercise Program; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Thrombocytopenia, Thrombosis, Cardiac Disease, Coronary Artery Bypass Surgery
Interventions: Angiomax (bivalirudin) anticoagulant; Drug
Lead sponsor: The Medicines Company; Industry
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Autonomic Nerve Block
Interventions: Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine, Pecto-intercostal Fascial Block with normal saline; Procedure
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Off Pump Coronary Artery Bypass Surgery
Interventions: Vacuum Stabilizer System, Vacuum Positioner System, Blower/Mister, Proximal Seal System; Device
Lead sponsor: Maquet Cardiovascular; Industry
Eligibility: 22 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Stockton, California • Wausau, Wisconsin

Conditions: Mitral Valve Insufficiency
Interventions: Mitral valve surgery; Procedure
Lead sponsor: Atlantic Health System; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Morristown, New Jersey

Conditions: Nitric Oxide, Cardiac Surgery, Cardiopulmonary Bypass, Adult Patients Undergoing Cardiovascular Surgery With Cardiopulmonary Bypass
Interventions: Nitric Oxide Gas, Standard Care Arm; Drug
Lead sponsor: Xijing Hospital; Other
Eligibility: 18 Years and older
Enrollment: 3,650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiac Surgery
Interventions: Human platelets; Biological
Lead sponsor: Cellphire Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 16
States / cities: Birmingham, Alabama • Aurora, Colorado • Washington D.C., District of Columbia + 12 more

Conditions: Patients Undergoing Cardiac Surgery
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Endothelial Dysfunction, Hemolysis Intravascular, Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions: Nitric Oxide, Reactive Hyperemia Index, Endothelial Cells Collection; Drug · Diagnostic Test · Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Coronary Artery Bypass Grafting, Mitral Valve Surgery, Low Cardiac Output Syndrome
Interventions: Levosimendan, Placebo; Drug
Lead sponsor: Tenax Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 882 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 49
States / cities: Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more

Conditions: Cognitive Disorders, Delirium, Acute Kidney Injury
Interventions: Ketamine, Propofol; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 75 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Coronary Artery Disease
Interventions: atrial tissue sample; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
Interventions: EEG Monitoring, Ropivacaine, Ketamine, Remifentanil, Dexmedetomidine, Rocuronium, Propofol; Device · Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 60 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Coronary Syndrome (ACS)
Interventions: cangrelor, Placebo; Drug · Other
Lead sponsor: The Medicines Company; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 221 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery(CABG)
Interventions: EA-230 90mg/kg/hour, Placebo; Drug
Lead sponsor: EBI Anti Sepsis BV; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Rochester, Minnesota • Pittsburgh, Pennsylvania

Conditions: Congenital Heart Disease
Interventions: transfusion strategy, Low Hb transfusion group; Other
Lead sponsor: University of Rochester; Other
Eligibility: 4 Months to 7 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
Interventions: Active Colchicine, Active Placebo; Drug
Lead sponsor: Population Health Research Institute; Other
Eligibility: 55 Years and older
Enrollment: 3,209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 8
States / cities: Weston, Florida • Detroit, Michigan • Stony Brook, New York + 5 more

Conditions: Cardiac Surgery
Interventions: MIB-626, Placebo; Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiac Surgery Requiring Cardiopulmonary Bypass, Brain Injury, Congenital Heart Defect
Interventions: Collecting discarded blood samples; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Up to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Diseases, Hyperglycemia
Interventions: Remifentanil, Fentanyl; Drug
Lead sponsor: Kathirvel Subramaniam; Other
Eligibility: 18 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Atrial Fibrillation
Interventions: Omega -3 fatty acids, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 1,516 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Preoperative Care, Surgery--Complications, Myocardial Infarction
Interventions: Not listed
Lead sponsor: Centre hospitalier de l'Université de Montréal (CHUM); Other
Eligibility: 45 Years and older
Enrollment: 15,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 5
States / cities: Winston-Salem, North Carolina • Cleveland, Ohio • Houston, Texas

Search by objective public record fields.

Phase II Study To Evaluate The Safety and Efficacy of Hemoglobin Raffimer in Patients Undergoing First Time CABG Surgery

MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery)

Changes in Fitness and Strength in Postoperative Cardiac Patients Undergoing Exercise Therapy: Biological and Functional Mechanisms of Recovery

Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)

Sternotomy PIFB Block in Open Heart Surgery

Getinge's Beating Heart Product Family Post-Market Clinical Follow-up (PMCF) Study

MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve Surgery

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass

DMSO Cryopreserved Platelets in Cardiopulmonary Bypass Surgery (CRYPTICS)

Measurement of Pulmonary Transit Time by Echocardiography: Comparison With Cardiac MRI

Effects of Nitric Oxide on the Endothelium During Hemolysis.

Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

Expression of Angiogenic Factors in Myocardial Tissue

Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

Maintenance of Platelet Inhibition With Cangrelor

A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.

Transfusion Strategies in Pediatric Cardiothoracic Surgery

Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)

Nicotinamide Mononucleotide in Patients Undergoing Cardiac Surgery

The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

Remifentanil and Glycemic Response in Cardiac Surgery

Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation

Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study