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ClinicalTrials.gov public records Last synced Jul 22, 2026, 8:42 AM EDT

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Showing 1–24 of 72 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pediatric Intensive Care Unit Clear all
Completed Not applicable Interventional

Meaning Making While Your Child is in Intensive Care

NCT05627531
View directory record Official record
Conditions
Narrative Medicine
Interventions
Narrative Medicine
Behavioral
Lead sponsor
Akron Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Phase 4 Interventional Results available

Ideal Steroids for Asthma Treatment in the PICU

NCT03900624
View directory record Official record
Conditions
Asthma Childhood
Interventions
Dexamethasone
Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Jul 22, 2026, 8:42 AM EDT
Recruiting No phase listed Observational

Rapid-Response EEG in Children With Suspected Status Epilepticus

NCT06564662
View directory record Official record
Conditions
Status Epilepticus, Coma
Interventions
Rapid Response EEG
Device
Lead sponsor
Children's Hospital at Montefiore
Other
Eligibility
2 Years to 18 Years
Enrollment
60 participants
Timeline
2021 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Phase 4 Interventional

Study of the Use of Coated Venous Catheters in the Critically Ill Child

NCT00202813
View directory record Official record
Conditions
Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter
Interventions
Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter
Device
Lead sponsor
Corewell Health West
Other
Eligibility
Up to 18 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 7, 2024 · Synced Jul 22, 2026, 8:42 AM EDT
Withdrawn Not applicable Interventional

Improving Sleep in the Pediatric Intensive Care Unit

NCT00178321
View directory record Official record
Conditions
Critically Ill
Interventions
earplugs
Device
Lead sponsor
University of Rochester
Other
Eligibility
1 Year to 15 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Jul 22, 2026, 8:42 AM EDT
Terminated Phase 2 Interventional Results available

Epinephrine in the Pediatric Intensive Care Unit: A Dose-Effect Trial

NCT05327556
View directory record Official record
Conditions
Hypotension
Interventions
Epinephrine 0.5 mcg/kg, Epinephrine 1 mcg/kg
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 25 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Phase 3 Interventional Results available

Study Evaluating Safety and Efficacy of Dexmedetomidine (DEX) in Intubated and Mechanically Ventilated Pediatric Intensive Care Unit (PICU) Subjects

NCT00875550
View directory record Official record
Conditions
Sedation
Interventions
Dexmedetomidine, Midazolam, Fentanyl, Morphine
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
1 Month to 16 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
33
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Loma Linda, California + 27 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2015 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

NCT00549393
View directory record Official record
Conditions
Nosocomial Infections
Interventions
2% Chlorhexidine gluconate cloth
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Months to 25 Years
Enrollment
5,659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Jul 22, 2026, 8:42 AM EDT
Suspended Not applicable Interventional

The Ketogenic Diet for Pediatric Acute Brain Injury

NCT02174016
View directory record Official record
Conditions
Acute Brain Injuries
Interventions
Ketogenic diet
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
1 Year to 17 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Not applicable Interventional

Primary Intensivists and Primary Nurses to Decrease Pediatric ICU Length of Stay

NCT03364933
View directory record Official record
Conditions
ICU Length of Stay
Interventions
Primary intensivist and nurses
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2020 · Synced Jul 22, 2026, 8:42 AM EDT
Recruiting Not applicable Interventional

Effect of Giving Reduced Fluid in Children After Trauma

NCT04201704
View directory record Official record
Conditions
Critical Illness, Pediatrics, General Surgery, Fluid Therapy, Wounds and Injuries
Interventions
Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume, Platelets volume
Other
Lead sponsor
Columbia University
Other
Eligibility
6 Months to 15 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Buffalo, New York • New York, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Not applicable Interventional Results available

Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit

NCT03749330
View directory record Official record
Conditions
Communication, Critical Illness
Interventions
CICU Team And Loved Ones Communicating (CICU TALC)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Jul 22, 2026, 8:42 AM EDT
Completed No phase listed Observational

BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia

NCT02220790
View directory record Official record
Conditions
Invasive Candidiasis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
120 Days to 18 Years
Enrollment
515 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
19
States / cities
Little Rock, Arkansas • Orange, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Jul 22, 2026, 8:42 AM EDT
Recruiting Not applicable Interventional

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

NCT04989790
View directory record Official record
Conditions
Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 18 Years
Enrollment
1,440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
11
States / cities
Madera, California • Orlando, Florida • Louisville, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Not applicable Interventional Results available

Improving Communication in the PICU: The Navigate Study

NCT02333396
View directory record Official record
Conditions
Communication
Interventions
PICU Supports, Educational Brochure
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 22, 2026, 8:42 AM EDT
Enrolling by invitation Not applicable Interventional

Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit

NCT07108374
View directory record Official record
Conditions
Red Blood Cell Transfusions
Interventions
Implementation strategies to increase use of transfusion recommendations
Other
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Palo Alto, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Jul 22, 2026, 8:42 AM EDT
Active, not recruiting Not applicable Interventional

PROSpect: Prone and Oscillation Pediatric Clinical Trial

NCT03896763
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome in Children
Interventions
Either supine or prone positioning and either CMV or HFOV
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
2 Weeks to 20 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Not applicable Interventional

Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit

NCT03453814
View directory record Official record
Conditions
Critical Illness
Interventions
Music Therapy
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
5 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Jul 22, 2026, 8:42 AM EDT
Completed Phase 3 Interventional Results available

Age of Blood in Children in Pediatric Intensive Care Units

NCT01977547
View directory record Official record
Conditions
Anemia
Interventions
Short storage RBC age
Biological
Lead sponsor
Washington University School of Medicine
Other
Eligibility
3 Days to 15 Years
Enrollment
1,538 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
20
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Jul 22, 2026, 8:42 AM EDT
Withdrawn Phase 4 Interventional

Dexmedetomidine Cycling and Sleep in the Pediatric ICU

NCT05003102
View directory record Official record
Conditions
Critical Illness, Sedation Complication, Delirium
Interventions
Dexmedetomidine Hydrochloride - Cycling, Fentanyl - PICU Standard, Dexmedetomidine Hydrochloride - PICU Standard
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
12 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Jul 22, 2026, 8:42 AM EDT
Active, not recruiting Not applicable Interventional

Situation Awareness Incorporating Multidisciplinary Teams Reduce Arrests In the Pediatric ICU

NCT06553534
View directory record Official record
Conditions
In-hospital Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
SAMURAI PICU Bundle
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
5
States / cities
Chicago, Illinois • Akron, Ohio • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Jul 22, 2026, 8:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Decreasing Catheter-Associated Urinary Tract Infections in the Pediatric Intensive Care Unit

NCT00672503
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Not listed
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 17 Years
Enrollment
321 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 11, 2011 · Synced Jul 22, 2026, 8:42 AM EDT
Completed No phase listed Observational

Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.

NCT03744169
View directory record Official record
Conditions
Pediatric Respiratory Diseases, Respiratory Failure
Interventions
Lung ultrasound, Clinical exam, Chest x-ray
Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Up to 18 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 22, 2020 · Synced Jul 22, 2026, 8:42 AM EDT
Recruiting Not applicable Interventional

PICU-related Sleep and Circadian Dysregulation Pilot Study

NCT06505447
View directory record Official record
Conditions
Circadian Dysrhythmia, Sleep Disturbance, Critical Illness, Children, Only
Interventions
Daytime light exposure, Daytime restricted feeding
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
3 Years to 6 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 22, 2026, 8:42 AM EDT