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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pelvic Floor Prolapse Clear all
Completed No phase listed Observational

GYNECARE PROSIMA* Pelvic Floor Repair System for Pelvic Organ Prolapse

NCT00521066
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
GYNECARE PROSIMA* Pelvic Floor Repair System
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
5
States / cities
Naples, Florida • Dearborn, Michigan • Grand Rapids, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational Results available

Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study

NCT01378065
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP)
Interventions
Restorelle Direct Fix A&P
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • Marshall, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pudendal Nerve Block in Vaginal Surgery

NCT04198714
View directory record Official record
Conditions
Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse, Pudendal Neuralgia, Surgery
Interventions
Pudendal block
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 14, 2026, 8:54 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Robotic Assisted Sacral Colpopexy : A Prospective Study Assessing Outcomes With Learning Curves

NCT01535833
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Device- Robotic sacral colpopexy
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational

Post-operative Cognitive Function Following Pelvic Floor Surgery

NCT04554550
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
60 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 24, 2022 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Educating Women About Pelvic Floor Disorders During Pregnancy

NCT05440539
View directory record Official record
Conditions
Pelvic Floor Disorders, Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Written Handouts, Interactive Workshop
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Vaginal Tactile Imaging in Assessment of Pelvic Floor Conditions

NCT02294383
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Princeton, New Jersey • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Validation of Transvaginal Tactile Imaging

NCT01491334
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years and older · Female only
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Princeton, New Jersey • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 24, 2014 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 14, 2026, 8:54 AM EDT
Terminated Phase 4 Interventional Results available

Hormonal Status on Blood Flow and Tissue in Pelvic Organ Prolapse

NCT01886794
View directory record Official record
Conditions
Pelvic Floor Disorders
Interventions
Postmenopausal, topical vaginal estrogen cream, Placebo Comparator: Postmenopausal, topical placebo cream
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
21 Years to 70 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Not applicable Interventional

ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study

NCT02021279
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
MatriStem Pelvic Floor Matrix, native tissue repair
Device · Procedure
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older · Female only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
13
States / cities
Stanford, California • Weston, Florida • Grand Rapids, Michigan + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational

Restorelle® Mesh Versus Native Tissue Repair for Prolapse

NCT02162615
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior, Native Tissue Repair Posterior
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
33
States / cities
Agoura Hills, California • Stanford, California • Denver, Colorado + 30 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Sep 14, 2026, 8:54 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy

NCT07175805
View directory record Official record
Conditions
Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder, Pelvic Organ Prolapse, Weight Loss, Fecal Incontinence, Bariatric Surgery, glp1 Agonist
Interventions
Bariatric Surgery, GLP1 receptor agonist
Procedure · Drug
Lead sponsor
Hartford HealthCare
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery

NCT03048682
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence,Stress, Surgery
Interventions
Foley catheter - Early Voiding Trial, Foley catheter - Late Voiding Trial
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Weston, Florida • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 14, 2026, 8:54 AM EDT
Not listed Not applicable Interventional

The Effect of Preemptive Levator Ani Injections on Pain After Pelvic Reconstructive Surgery

NCT04428320
View directory record Official record
Conditions
Pelvic Floor Prolapse, Surgery, Pain, Postoperative
Interventions
Pelvic floor injection
Procedure
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Phase 4 Interventional Results available

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

NCT02431897
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urogenital Prolapse, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Conjugated Estrogens Cream, Placebo Cream
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
48 Years and older · Female only
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Birmingham, Alabama • Providence, Rhode Island • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Axis™ Allograft Dermis for Female Pelvic Floor Repair: a Prospective Post Market Study

NCT01541748
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Axis
Other
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
5
States / cities
Weston, Florida • Cambridge, Massachusetts • Grand Rapids, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Sep 14, 2026, 8:54 AM EDT
Terminated Not applicable Interventional Results available

Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse

NCT01648751
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Vaginal estrogen, Placebo
Drug
Lead sponsor
Pamela Moalli
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

What is the Prevalence of Female Pelvic Floor Disorders in Minnesota?

NCT03536221
View directory record Official record
Conditions
Prolapse, Urinary Incontinence, Fecal Incontinence, Bladder Pain Syndrome
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational

A Multi Center Study to Validate a Condition-specific Measure of Sexual Health in Women With Pelvic Floor Disorders

NCT00952406
View directory record Official record
Conditions
Pelvic Floor Disorders, Sexual Dysfunction, Incontinence, Pelvic Organ Prolapse
Interventions
Survey
Other
Lead sponsor
International Urogynecological Society
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
877 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
9
States / cities
San Diego, California • Evanston, Illinois • Minneapolis, Minnesota + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 14, 2026, 8:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction

NCT01320631
View directory record Official record
Conditions
Sacral Colpopexy, Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 14, 2026, 8:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Nitrofurantoin and Urinary Tract Infections (UTIs)

NCT00678041
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Nitrofurantoin, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Sep 14, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional

Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration

NCT07544667
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP), Cystocele, Pelvic Floor Disorder
Interventions
Poly-L-Lactic Acid (Sculptra) injection, Placebo injection (sterile water)
Device · Other
Lead sponsor
Cassandra Kisby
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 14, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pelvic Floor Disorder Assessment of Knowledge and Symptoms: an Educational Model in Spanish-Speaking Women

NCT04829721
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urinary Incontinence, Patient Education
Interventions
Educational Intervention with video
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Sep 14, 2026, 8:54 AM EDT