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Showing 25–43 of 19 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Pelvic Floor Prolapse Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor

NCT01778985
View directory record Official record
Conditions
Pelvic Organ Prolapse, Menopause
Interventions
Premarin, Placebo
Drug · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Jul 22, 2026, 1:30 PM EDT
Completed No phase listed Observational

Vaginal Tactile Imaging for Pelvic Floor Prolapse

NCT02925585
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Pre/post imaging
Other
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years and older · Female only
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
5
States / cities
Tampa, Florida • Princeton, New Jersey • Allentown, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2019 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Phase 2 Interventional

Materna Prep Study Phase II

NCT06126328
View directory record Official record
Conditions
Vaginal Delivery, Pelvic Organ Prolapse
Interventions
Materna Prep Device
Device
Lead sponsor
Materna Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Mountain View, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2024 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Promoting Effective Recovery From Labor Urinary Incontinence (PERL)

NCT00506116
View directory record Official record
Conditions
Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
Interventions
Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing, Data collection
Behavioral · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 30, 2007 · Synced Jul 22, 2026, 1:30 PM EDT
Completed No phase listed Observational Results available

Pelvic Floor Repair Systems for Prolapse Repair

NCT00638235
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
AMS Apogee™ with IntePro, AMS Apogee™ with Intexen LP, AMS Perigee™ with IntePro, AMS Perigee™ with IntePro Lite, AMS Apogee™ with IntePro Lite, AMS Elevate™ Apical & Posteiror with IntePro Lite, AMS Elevate™ Apical & Posteiror with IntXen LP, AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 1, For Study Use Only), AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 2)
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
725 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
17
States / cities
Downey, California • Wellington, Florida • Alpharetta, Georgia + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2016 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pudendal Nerve Block in Vaginal Surgery

NCT04198714
View directory record Official record
Conditions
Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse, Pudendal Neuralgia, Surgery
Interventions
Pudendal block
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Phase 4 Interventional Results available

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

NCT02431897
View directory record Official record
Conditions
Pelvic Organ Prolapse, Urogenital Prolapse, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Conjugated Estrogens Cream, Placebo Cream
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
48 Years and older · Female only
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Birmingham, Alabama • Providence, Rhode Island • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Educating Women About Pelvic Floor Disorders During Pregnancy

NCT05440539
View directory record Official record
Conditions
Pelvic Floor Disorders, Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Written Handouts, Interactive Workshop
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jul 22, 2026, 1:30 PM EDT
Completed No phase listed Observational

Do Patients With Early Post Operative Recurrence of Pelvic Organ Prolapse Have a Genetic Predisposition?

NCT01614587
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Jul 22, 2026, 1:30 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Digital Care Programs for Female Pelvic Health

NCT05513417
View directory record Official record
Conditions
Pelvic Floor Disorders, Pelvic Pain, Pelvic Organ Prolapse, Pelvic Floor Muscle Weakness, Pelvic Pain Syndrome
Interventions
Bloom Pod
Device
Lead sponsor
Sword Health, SA
Industry
Eligibility
18 Years to 99 Years · Female only
Enrollment
50,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Jul 22, 2026, 1:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Validation of Transvaginal Tactile Imaging

NCT01491334
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Artann Laboratories
Industry
Eligibility
21 Years and older · Female only
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Princeton, New Jersey • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 24, 2014 · Synced Jul 22, 2026, 1:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Robotic Assisted Sacral Colpopexy : A Prospective Study Assessing Outcomes With Learning Curves

NCT01535833
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Device- Robotic sacral colpopexy
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Jul 22, 2026, 1:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction

NCT01320631
View directory record Official record
Conditions
Sacral Colpopexy, Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Therapy on Quality of Life and Function Following Vaginal Surgery Reconstructive Surgery

NCT01403701
View directory record Official record
Conditions
Quality of Life, Pelvic Floor Distress and Impact Scores, Sexual Function Scores
Interventions
Physical therapy
Behavioral
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Not applicable Interventional

ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study

NCT02021279
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
MatriStem Pelvic Floor Matrix, native tissue repair
Device · Procedure
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older · Female only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
13
States / cities
Stanford, California • Weston, Florida • Grand Rapids, Michigan + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Jul 22, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Jul 22, 2026, 1:30 PM EDT
Terminated No phase listed Observational

Exair® Versus Native Tissue Repair for Prolapse

NCT02162628
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Exair Prolapse Repair System, Total Native Tissue Repair
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
13
States / cities
Savannah, Georgia • Fort Wayne, Indiana • Dearborn, Michigan + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Jul 22, 2026, 1:30 PM EDT
Terminated No phase listed Observational

Pelvic Floor Disorders Among Sexual Minoritized Women

NCT05072158
View directory record Official record
Conditions
Sexual Function Disturbances, Pelvic Organ Prolapse, Urinary Incontinence, Fecal Incontinence
Interventions
None, this is an observational study
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Jul 22, 2026, 1:30 PM EDT
Completed No phase listed Observational

GYNECARE PROSIMA* Pelvic Floor Repair System for Pelvic Organ Prolapse

NCT00521066
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
GYNECARE PROSIMA* Pelvic Floor Repair System
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
5
States / cities
Naples, Florida • Dearborn, Michigan • Grand Rapids, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Jul 22, 2026, 1:30 PM EDT