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ClinicalTrials.gov public records Last synced Oct 8, 2026, 4:46 PM EDT

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Showing 97–120 of 229 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pelvic Organ Prolapse Clear all
Completed No phase listed Observational

Same Day Discharge Following Pelvic Reconstructive Surgery

NCT04804826
View directory record Official record
Conditions
Same Day Discharge, Pelvic Organ Prolapse, Total Vaginal Hysterectomy
Interventions
Pelvic Reconstructive Surgery
Procedure
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

Uterosacral Ligament Suspension Clip

NCT02700997
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Vascular Clip
Device
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2018 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension

NCT05688059
View directory record Official record
Conditions
Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
Interventions
Absorbable Suture and Permanent Suture
Other
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management

NCT07856654
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP), Postoperative Pain, Urogynecology
Interventions
Suzetrigine, Placebo
Drug
Lead sponsor
Aditi Talkad
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Improving Female Sexual Wellness

NCT04824820
View directory record Official record
Conditions
Sexuality, Sexual Dysfunction, Sexual Desire Disorder, Hypoactive Sexual Desire Disorder, Orgasmic Disorder, Pelvic Organ Prolapse, Urinary Incontinence, Interstitial Cystitis, Pelvic Floor Disorders, Female Sexual Dysfunction
Interventions
Vibrator
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 8, 2026, 4:46 PM EDT
Recruiting Not applicable Interventional

Accelerometer Measured Early Recovery After Prolapse Surgery

NCT07218016
View directory record Official record
Conditions
Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Patient Education
Interventions
Postoperative Exercise regimen
Behavioral
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
18 Years to 99 Years · Female only
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
San Diego, California • Chicago, Illinois • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Post Operative Morbidity in Older Women With Pelvic Organ Prolapse

NCT01967446
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
60 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Expedited Versus Restrictive: Limitations on Activity Following Surgical Treatment of Prolapse

NCT04329715
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Expedited postoperative activity instructions, Standard postoperative activity restructions
Behavioral
Lead sponsor
Duke University
Other
Eligibility
Female only
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 4 Interventional Results available

IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair

NCT02155738
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
IV Acetaminophen, IV normal saline
Drug
Lead sponsor
Halina M Zyczynski, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Patient Preparedness for Pelvic Organ Prolapse Surgery

NCT03836365
View directory record Official record
Conditions
Pelvic Organ Prolapse, Patient Preparedness
Interventions
Preoperative counseling office visit, Preoperative counseling phone call
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 99 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 8, 2026, 4:46 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Use of Pre-Emptive Pudendal Nerve Block for Pelvic Reconstructive Surgery

NCT02409498
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
pudendal block, no pudendal block
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension

NCT02888093
View directory record Official record
Conditions
Pelvic Organ Prolapse, Cystocele, Uterine Prolapse
Interventions
Absorbent suture (polydioxanone) and Permanent suture (Gore-Tex CV2)
Device
Lead sponsor
Joseph Kowalski
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Voiding Assessment Based on Minimum Spontaneous Void of 150 mL Compared to Retrograde Fill Method After Female Pelvic Floor Reconstructive Surgery

NCT03539107
View directory record Official record
Conditions
Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Retrograde bladder fill, spontaneous void
Procedure · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 8, 2026, 4:46 PM EDT
Not yet recruiting Phase 4 Interventional

Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery

NCT07600697
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
Interventions
Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Preoperative Fiber on Postoperative Bowel Function

NCT04882995
View directory record Official record
Conditions
Constipation, Prolapse, Vaginal
Interventions
Psyillium fiber
Dietary Supplement
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Phase 4 Interventional Results available

Intraperitoneal Bupivacaine for Pelvic Organ Prolapse

NCT06120530
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Bupivacaine, Saline
Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Carmel, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy

NCT07175805
View directory record Official record
Conditions
Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder, Pelvic Organ Prolapse, Weight Loss, Fecal Incontinence, Bariatric Surgery, glp1 Agonist
Interventions
Bariatric Surgery, GLP1 receptor agonist
Procedure · Drug
Lead sponsor
Hartford HealthCare
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy

NCT00564083
View directory record Official record
Conditions
Uterine Prolapse
Interventions
sacral colpopexy
Procedure
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 22, 2011 · Synced Oct 8, 2026, 4:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Using a Sheathed Speculum to Visualize and Access the Cervix In Women With Excessive Vaginal Tissue

NCT01409902
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145
View directory record Official record
Conditions
Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
Interventions
Preoperative Pessary Use
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 8, 2026, 4:46 PM EDT
Active, not recruiting Not applicable Interventional

Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)

NCT07120945
View directory record Official record
Conditions
Uterine Fibroids (UF), Menstrual Disorders, Adenomyosis of Uterus, Endometriosis, Uterine Prolapse, Precancerous/Nonmalignant Condition, Cervical Cancer, Endometrial Cancer, Ovarian Cancer
Interventions
Robotic Assisted-Surgery (RAS) Hysterectomy
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
22 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
5
States / cities
Jacksonville, Florida • Tampa, Florida • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional

Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse

NCT03005977
View directory record Official record
Conditions
Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Urodynamics
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 8, 2026, 4:46 PM EDT
Recruiting Not applicable Interventional

Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery

NCT05321134
View directory record Official record
Conditions
Colo-rectal Cancer, Rectal Prolapse, Colostomy Stoma, Colorectal Disorders
Interventions
Single port robotic colorectal surgical procedure
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 8, 2026, 4:46 PM EDT
Completed Not applicable Interventional Results available

Impact of Decision Aids in Urogynecology

NCT04369404
View directory record Official record
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence, Overactive Bladder
Interventions
Pelvic organ prolapse decision aid, Stress urinary incontinence decision aid, Overactive bladder decision aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 95 Years · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 8, 2026, 4:46 PM EDT