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ClinicalTrials.gov public records Last synced Nov 2, 2026, 5:45 PM EST

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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Penetrating Injury Clear all
Completed Phase 2 Interventional Results available

Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma

NCT01411852
View directory record Official record
Conditions
Blunt Trauma, Penetrating Wound, Hemorrhagic Shock
Interventions
0.9% Sodium Chloride 250 mL bolus, 0.9% Sodium Chloride 2000 mL bolus
Drug
Lead sponsor
University of Washington
Other
Eligibility
15 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
5
States / cities
Birmingham, Alabama • Portland, Oregon • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2015 · Synced Nov 2, 2026, 5:45 PM EST
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

A Study of VAX-ID® 2200, a New Device for Intradermal Injections

NCT07898111
View directory record Official record
Conditions
Sharps Injuries
Interventions
VAX-ID® 2200
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Nov 2, 2026, 5:45 PM EST
Completed Phase 2 Interventional Results available

Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Participants With Traumatic Brain Injury

NCT03095066
View directory record Official record
Conditions
Neurobehavioral Disinhibition
Interventions
Placebo, AVP-786-28, AVP-786-42.63
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
54
States / cities
Tuscaloosa, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional

Cesarean Wound Closure in Women With BMI 40 or Greater

NCT02549131
View directory record Official record
Conditions
C.Delivery; Penetration, Pregnant Uterus, by Instrument, Obesity
Interventions
Randomizing to Suture or Staple closure of Cesarean section
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Phoenix, Arizona • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Nov 2, 2026, 5:45 PM EST
Active, not recruiting Phase 4 Interventional

The PASTDUe Nutrition Ecosystem Project (PASTDUe)

NCT05127109
View directory record Official record
Conditions
Diet, Healthy, Food, Nutrition, Intensive Care, Abdominal Trauma, Surgery, Intra-abdominal Infection, Sepsis, Ischemic Bowel, Vascular, Penetrating Abdominal Trauma, Enteral Feeding, Oral
Interventions
Nutrition Ecosystem pathway, Comparator
Combination Product · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT04505293
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Relief of Symptoms of Post-traumatic Stress for Victims of Gun Violence

NCT03916614
View directory record Official record
Conditions
PTSD, Stress, Psychological, Gunshot Wound
Interventions
Screening Tool for Relief of Trauma (START), standard of care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Nov 2, 2026, 5:45 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Visual Prognosis in Non-Penetrating Corneal Blast Injuries

NCT00414219
View directory record Official record
Conditions
Corneal Foreign Body Following Blast Injury
Interventions
Visual quality of patients with corneal eye injuries
Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 30, 2010 · Synced Nov 2, 2026, 5:45 PM EST
Completed Phase 3 Interventional

Clinical Trial of New Elastomer for Maxillofacial Prosthetics

NCT00123097
View directory record Official record
Conditions
Facial Neoplasms, Head and Neck Neoplasms, Head Injuries, Penetrating, Birth Injuries
Interventions
Chlorinated polyethylene elastomer
Combination Product
Lead sponsor
University of Louisville
Other
Eligibility
21 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 7, 2017 · Synced Nov 2, 2026, 5:45 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections

NCT02620774
View directory record Official record
Conditions
Diabetes, Wound Infection, Healthy Volunteers
Interventions
Ceftolozane/tazobactam, Microdialysis Catheter Insertion
Drug · Procedure
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional

Trauma Services Intervention to Prevent Violence

NCT02642224
View directory record Official record
Conditions
Skin Injury Due to Violence, Gunshot Wound, Contact
Interventions
Social Work Case Management
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Nov 2, 2026, 5:45 PM EST
Not listed No phase listed Observational

Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03880188
View directory record Official record
Conditions
Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing, Disturbance of Wound Healing, Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 16, 2022 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of Blunt Needles for the Reduction of Needlestick Injuries During Cesarean Section

NCT00844636
View directory record Official record
Conditions
Glove Perforations, Needlestick Injuries
Interventions
Sharp needle, Blunt needles
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Nov 2, 2026, 5:45 PM EST
Completed Phase 3 Interventional Accepts healthy volunteers

Simulated Clinical Use Testing on Safe'N'Sound 1ML Stalked Passive Delivery System With Add-On Extended Finger Flanges

NCT02663635
View directory record Official record
Conditions
Needle Stick
Interventions
Safe'N'Sound
Device
Lead sponsor
Nemera La Verpilliere
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Nov 2, 2026, 5:45 PM EST
Completed No phase listed Observational

Social Determinants of Health in Patients With Penetrating Trauma Injuries Before and During the COVID-19 Pandemic

NCT06135610
View directory record Official record
Conditions
Penetrating Injury, COVID-19, Social Determinants of Health
Interventions
Postive SAR-CoV-2 PCR nasopharyngeal swab
Diagnostic Test
Lead sponsor
Kern Medical Center
Other
Eligibility
Not listed
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Nov 2, 2026, 5:45 PM EST
Withdrawn Phase 4 Interventional

Hepatitis C Virus Post-Exposure Prophylaxis for Health Care Workers

NCT01766115
View directory record Official record
Conditions
Viral Hepatitis C
Interventions
Telaprevir
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2014 · Synced Nov 2, 2026, 5:45 PM EST
Not yet recruiting Not applicable Interventional

Mississippi Violence Injury Prevention (VIP) Program

NCT06736730
View directory record Official record
Conditions
Gun Shot Wound
Interventions
Hospital-Linked Violence Intervention Program, Mobile Community Event Support, Unrestricted Cash Assistance
Behavioral
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Simulated Clinical Use Testing On Safety Lancets (Test B)

NCT03811444
View directory record Official record
Conditions
Needle Stick
Interventions
Haemolance Plus safety lancet, Prolance safety lancet, MediSafe Solo safety lancet
Device
Lead sponsor
HTL-Strefa S.A.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Nov 2, 2026, 5:45 PM EST
Completed No phase listed Observational

A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes

NCT06227871
View directory record Official record
Conditions
Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst, Pancreas; Fistula, Pancreas Abscess, Intra-Abdominal Abscess, Anastomotic Leak, Pancreas Injury
Interventions
Exploratory laparotomy
Procedure
Lead sponsor
Kern Medical Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Nov 2, 2026, 5:45 PM EST
Not yet recruiting No phase listed Observational

BRIDGE-US: Bridging Readiness in Deployed Neurotrauma Gaps for Excellence

NCT07636213
View directory record Official record
Conditions
Brain Injuries, Acute, Brain Trauma, Penetrating Head Injury, Traumatic Brain Injury
Interventions
Blood Sample Collection
Other
Lead sponsor
University of Chicago
Other
Eligibility
16 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Nov 2, 2026, 5:45 PM EST
Completed No phase listed Observational

Tree Branch Penetrating Injury

NCT05569447
View directory record Official record
Conditions
Penetrating Injury Neck
Interventions
Balloon Tamponade
Procedure
Lead sponsor
South Texas Health System McAllen
Other
Eligibility
50 Years and older · Male only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
McAllen, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Nov 2, 2026, 5:45 PM EST
Terminated Not applicable Interventional Results available

Feasibility of Evaluating XSTAT Use in the Prehospital Setting

NCT04663087
View directory record Official record
Conditions
Shock, Hemorrhagic, Injury Penetrating, Hemorrhage
Interventions
XSTAT, Standard of Care
Device · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
15 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Nov 2, 2026, 5:45 PM EST
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT03353246
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Nov 2, 2026, 5:45 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

ShotBlocker During Intramuscular Injection Randomized Control Trial

NCT06624176
View directory record Official record
Conditions
Neonatal Pain
Interventions
Bionix ShotBlocker, Swaddling, Sucrose administration, Masimo Rad-97 Oximeter probe
Device · Other
Lead sponsor
Lauren Fortier
Other
Eligibility
37 Weeks to 42 Weeks
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Nov 2, 2026, 5:45 PM EST