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Showing 1–24 of 127 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Perceived Pain Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Real-Time fMRI Feedback Effects on Pain Perception

NCT01588197
View directory record Official record
Conditions
Cognitive Pain Control
Interventions
Attention/Distraction Strategy, Stimulus Quality/Severity Strategy, Control Strategy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Social Presence and Perception in Virtual Reality on Pain

NCT03157362
View directory record Official record
Conditions
Chronic Pain, Widespread
Interventions
Near Non-Social, Near Social, Far Non-Social, Far Social
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Jul 22, 2026, 8:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sensory Processing in Subjects With Painful Bladder Syndrome

NCT00903643
View directory record Official record
Conditions
Painful Bladder Syndrome
Interventions
Physical examination
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Jul 22, 2026, 8:15 AM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?

NCT06865170
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee, Fear of Needles
Interventions
25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
40 Years to 89 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 22, 2026, 8:15 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Multisensory Integration and Pain Perception

NCT03471689
View directory record Official record
Conditions
Pain, Regulation, Self
Interventions
Mindfulness meditation, Positive reappraisal
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 23 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Jul 22, 2026, 8:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Pain Perception Between Males and Females Following Laparoscopic Cholecystectomy

NCT00575276
View directory record Official record
Conditions
Cholecystitis, Acute, Cholecystitis, Chronic
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Pain Perception During Chorionic Villus Sampling

NCT03140293
View directory record Official record
Conditions
Chorionic Villi Sampling
Interventions
Lidocaine injection, Gebauer Ethyl Chloride Spray
Drug
Lead sponsor
Angela Bianco
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional

Stress Inoculation Through Virtual Reality in the Pediatric Electrophysiology Laboratory

NCT02949401
View directory record Official record
Conditions
Stress, Psychological, Stress, Physiological, Anxiety, Pain Perception
Interventions
Use of Virtual Reality App
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
10 Years to 20 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Jul 22, 2026, 8:15 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

NCT06456411
View directory record Official record
Conditions
Breast Carcinoma, Kidney Carcinoma, Carcinoma
Interventions
Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention, Cold Stimulation
Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Phase 4 Interventional Results available

Buffered Lidocaine in the Pediatric Dental Patient

NCT04055116
View directory record Official record
Conditions
Pediatric Dentistry
Interventions
Buffered Lidocaine
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
4 Years to 17 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Jul 22, 2026, 8:15 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

The Effect of Transcutaneous Magnetic Stimulation on Acute Pain.

NCT03777137
View directory record Official record
Conditions
Pain Perception
Interventions
TMS (Rapid2, Magstim Corp)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Jul 22, 2026, 8:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Phenotyping IBS: Perceptions and Modulations of Visceral Sensations

NCT02693730
View directory record Official record
Conditions
Irritable Bowel Syndrome, Ulcerative Colitis, Inflammatory Bowel Disease
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Results available

Postoperative Environment on Pain Following Pelvic Reconstructive Surgery

NCT03379753
View directory record Official record
Conditions
Postoperative Pain
Interventions
music and positive images
Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of the Precision Spinal Cord Stimulator System at Sub-Perception Amplitude

NCT02314000
View directory record Official record
Conditions
Chronic Pain
Interventions
Precision or Precision Spectra Spinal Cord Stimulator System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
26
States / cities
Phoenix, Arizona • Carlsbad, California • Redwood City, California + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Prenatal Education on Perceptions of Epidural Acceptance

NCT01709591
View directory record Official record
Conditions
Labor Pain
Interventions
Prenatal education
Behavioral
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases

NCT00376922
View directory record Official record
Conditions
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Pain, Precancerous Condition, Psychosocial Effects of Cancer and Its Treatment
Interventions
music therapy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Phase 2 Interventional Results available

Investigation of AVACEN Thermal Exchange System for Fibromyalgia Pain

NCT01619579
View directory record Official record
Conditions
Fibromyalgia
Interventions
AVACEN Thermal Exchange System
Device
Lead sponsor
Avacen, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jul 22, 2026, 8:15 AM EDT
Withdrawn No phase listed Observational

Compounded Pain Creams and Patient Perception

NCT02024802
View directory record Official record
Conditions
Neurologic Pain, Nociceptive Pain
Interventions
Not listed
Lead sponsor
Marwood LowCost Pharmacy
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 7, 2014 · Synced Jul 22, 2026, 8:15 AM EDT
Completed No phase listed Observational

Effect of Spinal Cord Stimulation on Pain Thresholds and Sensory Perception in Chronic Pain Patients.

NCT01137617
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease

NCT02620488
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Guided Imagery
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Jul 22, 2026, 8:15 AM EDT
Withdrawn Phase 4 Interventional

Testosterone and Pain Sensitivity

NCT01689896
View directory record Official record
Conditions
Low Testosterone, Hypogonadism, Pain
Interventions
Testosterone Gel, Placebo Gel
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2015 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Direct Current Stimulation on Pain Perception

NCT01860950
View directory record Official record
Conditions
Pain
Interventions
anodal tDCS, cathodal tDCS, sham tDCS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Jul 22, 2026, 8:15 AM EDT
Withdrawn No phase listed Observational

Association Between Patients' Perceptions of Success in Post-op Pain Management and Overall Experience With Care

NCT02389907
View directory record Official record
Conditions
Postoperative Pain
Interventions
Not listed
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
9
States / cities
Bridgeport, Connecticut • Jupiter, Florida • Tamarac, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Jul 22, 2026, 8:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of High Intensity Interval Exercise on Executive Function

NCT02270528
View directory record Official record
Conditions
High Intensity Interval Exercise (HIIE), Pain Perception, Wisconsin Card Sorting Task
Interventions
Exercise, Cognitive Task
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Jul 22, 2026, 8:15 AM EDT