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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Perinatal Asphyxia Clear all
Completed Not applicable Interventional

Behavioral Activation for Perinatal Depression

NCT01401231
View directory record Official record
Conditions
Depression During Pregnancy
Interventions
Behavioral activation psychotherapy, Usual care
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Training for Addressing Perinatal Depression

NCT04919967
View directory record Official record
Conditions
Mood Disorders, Anxiety Disorders
Interventions
Virtual implementation protocol, e-learning toolkit
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Leominster, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 5, 2026, 2:30 PM EDT
Active, not recruiting Phase 3 Interventional

mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression

NCT05186272
View directory record Official record
Conditions
Post Partum Depression, Perinatal Depression
Interventions
Stress reduction program 'A', Stress reduction program 'B'
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Perinatal Depression Treatment in a Pediatric Setting- Pilot Phase

NCT00804739
View directory record Official record
Conditions
Postpartum Depression
Interventions
Mother-Infant Treatment Team
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2012 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

CoolCap Trial, Treatment of Perinatal Hypoxic-Ischemic Encephalopathy

NCT00383305
View directory record Official record
Conditions
Neonatal Hypoxic-Ischemic Encephalopathy (HIE)
Interventions
Cool-Cap
Device
Lead sponsor
Olympic Medical
Industry
Eligibility
1 Hour to 6 Hours
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2003
U.S. locations
19
States / cities
Little Rock, Arkansas • Oakland, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2006 · Synced Sep 5, 2026, 2:30 PM EDT
Active, not recruiting Not applicable Interventional

Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care

NCT04838210
View directory record Official record
Conditions
Pregnancy Related, Perinatal Depression
Interventions
EleVATE Group Care, Individual Prenatal Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
13 Years and older · Female only
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
Kansas City, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Pilot Study of Mothers and Babies Online in Home Visiting

NCT05714956
View directory record Official record
Conditions
Perinatal Depression
Interventions
Mothers and Babies Online (eMB)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
16 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Chicago, Illinois • Joliet, Illinois • Chariton, Iowa + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 5, 2026, 2:30 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

NCT05552053
View directory record Official record
Conditions
Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression, Depression, Postpartum, Perinatal Depression, Anxiety, Anxiety in Pregnancy, Stress, Psychological, Racism, Discrimination, Racial, Inflammation
Interventions
MWSH plus Candlelit Care, MWSH
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Online Collaborative Learning Intervention to Prevent Perinatal Depression

NCT02121015
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Share, Self-Directed
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Chicago, Illinois • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 5, 2026, 2:30 PM EDT
Active, not recruiting Not applicable Interventional

Perinatal Research on Improving Sleep and Mental Health

NCT05596318
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Digital CBT-I, Digital SHE
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Center M: Digital Health Innovation Pilot

NCT06000449
View directory record Official record
Conditions
Perinatal Depression
Interventions
Center M, Treatment as Usual
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Results available

A Pilot Randomized Trial of Video-based Family Therapy for Depressed Home Visited Mothers

NCT04741776
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression, Family Conflict
Interventions
Resilience Enhancement Skills Training, Problem-Solving Individual Therapy
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
15 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Activity During Birth for Prediction of Newborns at Risk for Brain Injury

NCT02445417
View directory record Official record
Conditions
Encephalopathy, Asphyxia Newborns
Interventions
Not listed
Lead sponsor
Sharp HealthCare
Other
Eligibility
36 Weeks to 44 Weeks
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Sep 5, 2026, 2:30 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy

NCT01765218
View directory record Official record
Conditions
Hypoxic Ischemic Encephalopathy
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Kristin R Hoffman
Other
Eligibility
Up to 6 Hours
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 5, 2026, 2:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health

NCT07217561
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety
Interventions
Doula Link
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Optimizing Clinical Screening and Management of Maternal Mental Health: Predicting Women at Risk for Perinatal Depression

NCT03144752
View directory record Official record
Conditions
Depression
Interventions
Not listed
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 44 Years · Female only
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

MomMoodBooster VA Program

NCT05196152
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression
Interventions
MomMoodBooster, Phone Coaching
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Integrated Chronotherapy for Perinatal Depression

NCT02053649
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Postpartum Depression
Interventions
Triple Chronotherapy, Usual Care
Behavioral · Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Results available

Personalized Integrated Chronotherapy for Perinatal Depression

NCT04364646
View directory record Official record
Conditions
Depression, Postpartum Depression, Prenatal Disorder, Circadian Dysregulation, Pregnancy Related, Sleep Disturbance
Interventions
Personalized Integrated Chronotherapy
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Glen Oaks, New York • Chapel Hill, North Carolina • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 5, 2026, 2:30 PM EDT
Recruiting Not applicable Interventional

Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals

NCT05897619
View directory record Official record
Conditions
Perinatal Anxiety, Perinatal Depression
Interventions
Experimental: Maya Perinatal Cognitive Behavioral Skills App
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Results available

Responsive e-Health Intervention for Perinatal Depression in Healthcare Settings

NCT03995316
View directory record Official record
Conditions
Perinatal Depression
Interventions
Treatment As Usual + MMB 2.0, Treatment As Usual Only
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Chicago, Illinois • Springfield, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 5, 2026, 2:30 PM EDT
Not listed Phase 2 Interventional

A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care

NCT04998721
View directory record Official record
Conditions
Depression, Postpartum, Efficacy, Self, Anxiety
Interventions
Promoting First Relationships-Brief, Perinatal Collaborative Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Intervention to Prevent Perinatal Depression and Promote Breastfeeding

NCT04128202
View directory record Official record
Conditions
Depression, Breastfeeding
Interventions
Sunnyside, Sunnyside Plus
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 25, 2021 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of the Alma Peer Mentoring Program for Pregnant Women Experiencing Depression

NCT02883686
View directory record Official record
Conditions
Depression, Depression, Postpartum
Interventions
Alma
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Sep 5, 2026, 2:30 PM EDT