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ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:27 AM EST

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Showing 49–71 of 71 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Perioperative Analgesia Clear all

Conditions: Laparoscopic Gastric Bypass Surgery, Ketamine
Interventions: Ketamine, Standard therapy; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 69 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Perioperative Pain
Interventions: adenosine; Drug
Lead sponsor: Xsira Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 8
States / cities: San Francisco, California • Miami, Florida • Augusta, Georgia + 5 more

Conditions: Hypnosis, Perioperative Care, Knee Arthroplasty, Total, Postoperative Pain, Postoperative Complications
Interventions: Hypnosis; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions: Infrared Pupillometry; Device
Lead sponsor: NeurOptics Inc; Industry
Eligibility: 3 Years to 17 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: San Francisco, California • Pittsburgh, Pennsylvania

Conditions: Head and Neck Cancer, Analgesia
Interventions: Tylenol, Oxycodone, Morphine, Gabapentin, toradol, Bupivacaine; Drug
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Postoperative Pain
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Pain
Interventions: Celecoxib, Placebo; Drug
Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 7
States / cities: Aurora, Colorado • Englewood, Colorado • Chicago, Illinois + 3 more

Conditions: Pain, Post Operative Analgesia, Opioid Consumption, Postoperative
Interventions: Lidocaine HCl 0.8% in D5W, Dextrose 5% in water; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 2,290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pain, Postoperative
Interventions: Caffeine, Placebo oral tablet; Drug
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Egg Harbor, New Jersey

Conditions: Pain, Post Operative, Anxiety, Opioid Use
Interventions: Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS); Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 70 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
Interventions: Ropivacaine, Normal saline; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Postoperative Pain
Interventions: Lidocaine and ketamine, Lidocaine, Ketamine, Placebo; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 420 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Weston, Florida

Conditions: Pain, Constipation, Nausea, Vomiting
Interventions: Lidocaine, Esmolol, Lidocaine + Esmolol (Combo); Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Liver Transplantation
Interventions: Methadone, ketamine, Hydromorphone, fentanyl; Drug
Lead sponsor: Lahey Clinic; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Burlington, Massachusetts

Conditions: Colon Cancer, Rectal Cancer, Colonic Diverticulosis
Interventions: TAP Block, Continuous Epidural Analgesia; Procedure
Lead sponsor: Trinity Health Michigan; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Fusion of Spine, Lumbar Region
Interventions: Acetaminophen IV Soln 10 MG/ML, Acetaminophen, Hydromorphone; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Ambulatory Surgery, Coughing
Interventions: Saline, Fentanyl; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Postoperative Pain Control, Opioid Consumption
Interventions: Ketamine, Placebo Ketamine, Lidocaine, Placebo Lidocaine, Acetaminophen, Placebo Acetaminophen, Gabapentin, Placebo Gabapentin, Celecoxib, Placebo Celecoxib; Drug
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Other Abortion, Spontaneous Abortion
Interventions: Gabapentin, Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tonsillitis
Interventions: Celecoxib, Placebo; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Analgesia, Cardiac Surgery
Interventions: Not listed
Lead sponsor: Kathirvel Subramaniam; Other
Eligibility: 60 Years to 110 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
Interventions: Methadone hydrochloride, Fentanyl/Hydromorphone; Drug
Lead sponsor: Duke University; Other
Eligibility: 6 Months to 4 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Laparoscopic Surgery
Interventions: Fentanyl, Labetalol, Esmolol; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Perioperative Ketamine for Pain With Gastric Bypass

Dose-Response of Adenosine for Perioperative Pain

Hypnosis for Symptom Management in Elective Orthopedic Surgery

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

Multimodal Pain Study in Free Flap Patients

Assessing the Efficacy of Intravenous Acetaminophen Versus the Oral Formulation for Perioperative Pain Treatment

Celebrex Total Knee Arthroplasty Study

The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery

Caffeine Study for Pain Control Following Total Joint Replacement

Music Therapy in the Treatment of Perioperative Anxiety and Pain

Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.

Perioperative Lidocaine and Ketamine in Abdominal Surgery

Effect of Lidocaine and Esmolol to Improve the Quality of Recovery

Reducing Pain With Methadone and Ketamine in Liver Transplant

Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery

The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion

Effect of Fentanyl on Coughing and Recovery After Anesthesia With an LMA Laryngeal Mask Airway)for Airway Management

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Gabapentin as an Adjunct to Perioperative Pain Management Regimens for Uterine Aspiration

Celecoxib as a Post-tonsillectomy Pain Medication

Precision Analgesia for Cardiac Surgery

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

Labetalol and Esmolol: Vital Signs and Post Operative Pain Management