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ClinicalTrials.gov public records Last synced Oct 9, 2026, 9:10 AM EDT

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Showing 49–72 of 575 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peripheral Arterial Disease (PAD) Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Onsite Tobacco Cessation Treatment for Patients With PAD

NCT05469698
View directory record Official record
Conditions
Tobacco Cessation, Peripheral Artery Disease
Interventions
Tobacco Treatment Research Program Standard Care
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Rehabilitation in Veterans With PAD

NCT02607046
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Exercise training, NMES
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Phase 3 Interventional

Endovascular Atherectomy Safety and Effectiveness Study

NCT01541774
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Phoenix Atherectomy System
Device
Lead sponsor
AtheroMed, Inc
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
14
States / cities
Mobile, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2014 · Synced Oct 9, 2026, 9:10 AM EDT
Terminated Phase 2 Interventional Results available

Efficacy and Safety of Intramuscular PDA-002 in Subjects With Diabetic Foot Ulcer With and Without PAD.

NCT02264288
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetic Foot
Interventions
PDA-002, Placebo
Biological · Other
Lead sponsor
Celularity Incorporated
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
45
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Results available

Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging

NCT02807779
View directory record Official record
Conditions
Peripheral Artery Disease, Vascular Disease, Critical Limb Ischemia
Interventions
Dexamethasone infusion, Drug coated balloon, Plain balloon angioplasty
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
35 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
2
States / cities
San Francisco, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

NCT01064440
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Low Dose VM202, High Dose VM202, Placebo
Biological · Other
Lead sponsor
Helixmith Co., Ltd.
Industry
Eligibility
18 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
13
States / cities
Birmingham, Alabama • Orange, California • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Not applicable Interventional

SHOWME-PAD (Peripheral Artery Disease)

NCT03190382
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Decision Support Tool
Other
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 24, 2024 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Heat Therapy to Reduce Pain and Improve Walking Tolerance

NCT03435835
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Control/Sham Treatment, Heat Therapy (HT)
Device
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Results available

Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD

NCT01785524
View directory record Official record
Conditions
Peripheral Arterial Disease, Type II Diabetes Mellitus
Interventions
Beetroot Juice (Beet-It Stamina Shot) and Exercise Training, Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
50 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Oct 9, 2026, 9:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Functional MRI of the Lower Extremities

NCT03423316
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Supervised exercise therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 9, 2026, 9:10 AM EDT
Terminated Not applicable Interventional

Yoga to Improve Physical Function and Maximal Walking Distance Among Patients With Peripheral Arterial Disease

NCT02007525
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Yoga intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
41 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 9, 2026, 9:10 AM EDT
Completed No phase listed Observational

PAD Registry and Fitbit Sub-Study Program

NCT03446014
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Fitbit Sub-Study
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 9, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetics of Peripheral Artery Genomics

NCT00615121
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Oct 9, 2026, 9:10 AM EDT
Not listed Phase 4 Interventional

Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI)

NCT04306471
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Evolocumab 140mg/mL Injector 1milliliter (mL) Pen x 3 for a monthly dose of 420 mg for 12 months., Placebo 1 milliliter (mL) Injector Pen x 3 monthly for 12 months
Drug · Other
Lead sponsor
Leonardo Clavijo
Other
Eligibility
40 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Complete Lesion Assessment With ffR and IVUS TechnologY

NCT01941030
View directory record Official record
Conditions
Peripheral Artery Disease, Critical Limb Ischemia
Interventions
Orbital Atherectomy System, Balloon Angioplasty
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
8
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Davenport, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Autologous Bone Marrow Mononuclear Cell Implantation for Moderate to Severe Peripheral Arterial Disease

NCT00919516
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Bone marrow mononuclear cell implantation
Procedure
Lead sponsor
The Vascular and Vein Center, Columbus, OH
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 11, 2014 · Synced Oct 9, 2026, 9:10 AM EDT
Completed No phase listed Observational Results available

TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions

NCT03306199
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Laser Atherectomy
Device
Lead sponsor
Spectranetics Corporation
Industry
Eligibility
Not listed
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houma, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Oct 9, 2026, 9:10 AM EDT
Not listed Not applicable Interventional

Assessment of the Utility of the Pantheris Small Vessel (SV) System

NCT04793581
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Atherectomy
Device
Lead sponsor
Avinger, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Grand Rapids, Michigan • Saint Clair Shores, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Static Muscular Stretching for Treatment of PAD

NCT04222751
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Ankle Splint
Device
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 100 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 9, 2026, 9:10 AM EDT
No Longer Available No phase listed Expanded access

Safety and Efficacy of Autologous Concentrated Bone Marrow Aspirate for Critical Limb Ischemia - Continued Access

NCT02474121
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases, Critical Limb Ischemia
Interventions
Bone marrow concentration device
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
21 Years and older
U.S. locations
9
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Indianapolis, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2020 · Synced Oct 9, 2026, 9:10 AM EDT
Completed No phase listed Observational

A Long Term Follow-up Study of AMG0001 in Subjects With Critical Limb Ischemia

NCT02974179
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Subjects from Study AG-CLI-0206 who received AMG0001
Biological
Lead sponsor
AnGes USA, Inc.
Industry
Eligibility
40 Years to 90 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)

NCT00687076
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ezetimibe, Niaspan, Statin therapy, Standard care, Aspirin, Clopidogrel, Placebo Niaspan, Placebo Ezetimibe, Percutaneous transluminal angioplasty (PTA)
Drug · Behavioral · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
40 Years to 80 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 9, 2026, 9:10 AM EDT
Not yet recruiting Not applicable Interventional

Below-the-Knee Interventions for Limb Salvage: Use of Multifunctional Angioplasty Balloon Catheters

NCT06906055
View directory record Official record
Conditions
Peripheral Arterial Disease Below the Knee, Peripheral Arterial Disease, Rutherford 4 and 5 with Possibility to Improve Vascularization
Interventions
Multicath, Standard of Care (SOC)
Device
Lead sponsor
Summa Therapeutics, LLC
Industry
Eligibility
18 Years to 120 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Vineland, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 9, 2026, 9:10 AM EDT
Completed Phase 1 Interventional

Pilot Study of PRT-201 Following Angioplasty in Patients With Peripheral Artery Disease (PAD)

NCT01616290
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
PRT-201
Drug
Lead sponsor
Proteon Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2015 · Synced Oct 9, 2026, 9:10 AM EDT