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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:53 AM EDT

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Showing 73–96 of 661 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peripheral Artery Diseases Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Improving Exercise Rehabilitation Efficacy Outcomes Veterans Peripheral Artery Disease

NCT05648630
View directory record Official record
Conditions
Peripheral Artery Disease (D058729), Oxidative Stress (D018384), Inflammation (D007249)
Interventions
PB125, Placebo, Exercise Rehabilitation
Dietary Supplement · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 5, 2026, 4:53 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)

NCT02805023
View directory record Official record
Conditions
Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions
BGC101 (autologous EnEPC preparation), Control medium
Biological
Lead sponsor
BioGenCell Ltd.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
3
States / cities
San Francisco, California • New Haven, Connecticut • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Motivational Interviewing (MI) for African Americans With Peripheral Arterial Disease (PAD)

NCT01321086
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Motivational Interviewing, PACE
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
Not listed
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Fairway, Kansas • Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 5, 2026, 4:53 AM EDT
Terminated No phase listed Observational

FIRE-PAD: Functional Improvement Through Revascularization of the Extremities for Peripheral Arterial Disease

NCT00274157
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Behavior, diet control, smoking cessation, exercize
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2008 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Phase 1 Interventional

A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion

NCT00418483
View directory record Official record
Conditions
Arterial Occlusive Diseases
Interventions
Plasmin (Human) 25 mg, Plasmin (Human) 50 mg, Plasmin (Human) 75 mg, Plasmin (Human) 100 mg, Plasmin (Human) 125 mg, Plasmin (Human) 150 mg, Plasmin (Human) 175 mg
Biological
Lead sponsor
Grifols Therapeutics LLC
Industry
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Oct 5, 2026, 4:53 AM EDT
Not listed Phase 2 Interventional

Evaluation of FM220 in Patients With Peripheral Arterial Disease (PAD)

NCT00146666
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Intermittent compression
Device
Lead sponsor
FlowMedic
Industry
Eligibility
40 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Jacksonville, Florida • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 17, 2009 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Chronic Total Occlusion Crossing With the Wildcat Catheter

NCT01174784
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Chronic TOtAl OcclusioN CrossiNg with thE WildCat CatheTer
Device
Lead sponsor
Avinger, Inc.
Industry
Eligibility
19 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
15
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2020 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Creatine Use and Muscle Stretching in Peripheral Artery Disease

NCT04471792
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Creatine monohydrate, Cellulose
Drug · Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 95 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 5, 2026, 4:53 AM EDT
Completed No phase listed Observational

Angio-Seal Evolution Device Registry

NCT00817349
View directory record Official record
Conditions
Peripheral Vascular Disease, Coronary Artery Disease, Peripheral Artery Disease, Arterial Occlusive Disease, Coronary Heart Disease
Interventions
Not listed
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
10
States / cities
Los Angeles, California • Ypsilanti, Michigan • Camden, New Jersey + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 5, 2026, 4:53 AM EDT
Recruiting No phase listed Observational

Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease

NCT06477289
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
12 Years to 25 Years
Enrollment
65 participants
Timeline
2024 – 2028
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Atrium iCAST Iliac Stent Pivotal Study

NCT00593385
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
iCAST covered stent
Device
Lead sponsor
Atrium Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
24
States / cities
Little Rock, Arkansas • Mountain View, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Oct 5, 2026, 4:53 AM EDT
Terminated Not applicable Interventional

Diamondback in Peripheral Vascular Disease

NCT03455374
View directory record Official record
Conditions
Peripheral Vascular Diseases, Critical Limb Ischemia
Interventions
Treatment with CSI atherectomy device
Device
Lead sponsor
Arkansas Heart Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease

NCT02719665
View directory record Official record
Conditions
Peripheral Arterial Disease, Claudication, Claudication, Intermittent, Vascular Occlusion, Vascular Calcification, Vascular Diseases, Osteoarthritis
Interventions
SPM Emulsion, Dose-modality, SPM Softgel, Dose-Modality, Placebo Softgel
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Phase 3 Interventional Results available

Trial to Evaluate the Safety & Efficacy of the Omnilink Elite™ Peripheral Balloon-Expandable Stent System in Subjects With Atherosclerotic de Novo or Restenotic Lesions in the Native Common Iliac Artery and/or Native External Iliac Artery

NCT01396525
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Omnilink Elite™ Peripheral Balloon-Expandable Stent System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 89 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Santa Clara, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 5, 2026, 4:53 AM EDT
Not listed Phase 4 Interventional

Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI)

NCT04306471
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Evolocumab 140mg/mL Injector 1milliliter (mL) Pen x 3 for a monthly dose of 420 mg for 12 months., Placebo 1 milliliter (mL) Injector Pen x 3 monthly for 12 months
Drug · Other
Lead sponsor
Leonardo Clavijo
Other
Eligibility
40 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Phase 2 Interventional

Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease

NCT00113009
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
VLTS-934
Drug
Lead sponsor
Valentis
Industry
Eligibility
40 Years to 78 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
32
States / cities
Birmingham, Alabama • Beverly Hills, California • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Nov 22, 2007 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Phase 3 Interventional Results available

EPIC Nitinol Stent System in the Treatment of Atherosclerotic Lesions in Iliac Arteries

NCT00896337
View directory record Official record
Conditions
Iliac Artery Stenosis
Interventions
Epic™ Nitinol Stent System, Anti-platelet therapy, Anti-coagulation therapy
Device · Drug
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
28
States / cities
Tucson, Arizona • Brandon, Florida • Fort Lauderdale, Florida + 24 more
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Oct 5, 2026, 4:53 AM EDT
Terminated Phase 2 Interventional Results available

Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease

NCT01731990
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Canakinumab (ACZ885), Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 85 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
8
States / cities
Phoenix, Arizona • Jacksonville, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

The PQ Bypass Pivotal IDE Intra-arterial Stent Graft Study

NCT04130737
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
TORUS Stent Graft System
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years to 90 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
32
States / cities
Mesa, Arizona • Phoenix, Arizona • Yuma, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Results available

Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD

NCT02553733
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Beetroot juice, Beetroot juice placebo
Drug
Lead sponsor
David N. Proctor, PhD
Other
Eligibility
21 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 5, 2026, 4:53 AM EDT
Not listed Not applicable Interventional

External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality

NCT02054416
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
ArtAssist© Device
Device
Lead sponsor
Temple University
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 8, 2016 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Texting for Mobility in Overweight/Obese Adults With Peripheral Artery Disease

NCT03694652
View directory record Official record
Conditions
Overweight and Obesity
Interventions
PACE, Diet, App, Face-to-face
Behavioral · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
50 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 5, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients

NCT05830721
View directory record Official record
Conditions
Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication, Limb Ischemia, Limb Ischemia, Critical
Interventions
MY01 + Standard of Care, 14-Gauge Slit Catheter + Standard of Care, Standard of Care
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 5, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)

NCT05358353
View directory record Official record
Conditions
Peripheral Arterial Disease, Critical Limb Ischemia
Interventions
Bare Temporary Spur Stent System
Device
Lead sponsor
ReFlow Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
48
States / cities
Jonesboro, Arkansas • Little Rock, Arkansas • Orange, California + 44 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 5, 2026, 4:53 AM EDT