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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Peripheral Nerve Injury Upper Limb Clear all
Recruiting Phase 4 Interventional

A Prospective, Randomized, Assessor-Blinded, Multicenter Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction

NCT07657182
View directory record Official record
Conditions
Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury, Upper Extremity Nerve Injury
Interventions
Avance Nerve Graft, Sural nerve autograft
Biological · Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jun 26, 2026, 2:12 AM EDT
Suspended Not applicable Interventional

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

NCT01693094
View directory record Official record
Conditions
Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Distal Radius Fractures, Trigger Finger
Interventions
Decision Aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jun 26, 2026, 2:12 AM EDT
Withdrawn No phase listed Observational

Nerve Transfers to Restore Hand Function in Spinal Cord Injury

NCT02861612
View directory record Official record
Conditions
Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
Interventions
Nerve Transfer Surgery
Procedure
Lead sponsor
Ottawa Hospital Research Institute
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 20, 2019 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interhemispheric Connectivity and Compensation

NCT05207878
View directory record Official record
Conditions
Peripheral Nerve Injury Upper Limb, Healthy
Interventions
STEGA-MRI
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jun 26, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

NCT03610763
View directory record Official record
Conditions
Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
Interventions
Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
Device · Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
3
States / cities
Louisville, Kentucky • Columbia, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries

NCT02313675
View directory record Official record
Conditions
Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
Interventions
Acetaminophen, Ketorolac Tromethamine, Saline
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Jun 26, 2026, 2:12 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Rebuilding Inter-limb Transfer in Cervical SCI

NCT06440538
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
PCMS + Contralateral Motor Training, PCMS + Rest, Sham PCMS + Contralateral Motor Training
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Two Injection Sites of Local Anesthetic for Hand Surgery

NCT02112006
View directory record Official record
Conditions
Hand Injury, Wrist Injury, Finger Injury
Interventions
0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.
Procedure
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 21, 2016 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Not applicable Interventional

Upper Extremity Surgery in Spinal Cord Injury

NCT01899664
View directory record Official record
Conditions
Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
Interventions
Nerve Transfer Surgery
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Jun 26, 2026, 2:12 AM EDT
Not yet recruiting Not applicable Interventional

Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test

NCT07158892
View directory record Official record
Conditions
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis, Trigger Digit, Dupuytren Contracture, Rotator Cuff Tendinopathy, De Quervain Disease
Interventions
Diagnostic Advance Care Planning Discussion, Informational Statement Only
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Jun 26, 2026, 2:12 AM EDT
Recruiting Phase 3 Interventional

This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.

NCT06616025
View directory record Official record
Conditions
Peripheral Nerve Injury Upper Limb, Peripheral Nerve Injury (PNI)
Interventions
NTX-001 (PEG-Fusion)
Combination Product
Lead sponsor
Neuraptive Therapeutics Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
21
States / cities
Orlando, Florida • Atlanta, Georgia • Chicago, Illinois + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Jun 26, 2026, 2:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals

NCT02587897
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Academic Coursework, Work-Related Hand Activities
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
3
States / cities
Loma Linda, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protective Brace to Prevent Hand and Arm Injuries

NCT00074893
View directory record Official record
Conditions
Cumulative Trauma Disorders, Carpal Tunnel Syndrome
Interventions
piezoelectric wrist brace
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
21 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2006 · Synced Jun 26, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional

Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI)

NCT06672458
View directory record Official record
Conditions
Spinal Cord Injuries, Peripheral Nerve Injuries
Interventions
MyndMove Short Term Therapy, Conventional Short Term Therapy, MyndMove Long Term Therapy
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jun 26, 2026, 2:12 AM EDT
Not listed Not applicable Interventional

mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation

NCT06023316
View directory record Official record
Conditions
Upper Limb Weakness Due to Central Neurologic Injury, Upper Limb Weakness Due to Peripheral Neurologic Injury, Upper Limb Weakness Due to Nerve Reconstruction, Upper Limb Weakness Due to Tendon Transfer Surgery, Stroke, Upper Limb Amputation
Interventions
mGain system
Device
Lead sponsor
Orthocare Innovations, LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Edmonds, Washington
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jun 26, 2026, 2:12 AM EDT
Not listed Not applicable Interventional

BMAC Nerve Allograft Study

NCT03964129
View directory record Official record
Conditions
Peripheral Nerve Injury Upper Limb
Interventions
Avance Nerve Graft with Autologous BMAC
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 74 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Baltimore, Maryland • Bethesda, Maryland • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Jun 26, 2026, 2:12 AM EDT
Not listed Not applicable Interventional

Nerve Block for Pain Control After Fracture Surgery

NCT05391464
View directory record Official record
Conditions
Ankle Fractures, Distal Radius Fracture
Interventions
Peripheral Nerve Block
Procedure
Lead sponsor
MaineGeneral Health
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Augusta, Maine
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Jun 26, 2026, 2:12 AM EDT
Withdrawn No phase listed Observational

Alternatives to Hand Therapy for Hand Surgery Patients

NCT03779958
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Trigger Finger, Ganglion Cysts, Distal Radius Fracture, Finger Fracture, De Quervain Syndrome
Interventions
Mobile App
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Jun 26, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional

Promoting Healing of Injured Nerves With Electrical Stimulation Therapy

NCT05884125
View directory record Official record
Conditions
Nerve Injury, Peripheral Nerve Injuries, Peripheral Nerve Injury Upper Limb, Nerve Palsy
Interventions
Checkpoint BEST System
Device
Lead sponsor
Checkpoint Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Jun 26, 2026, 2:12 AM EDT
Terminated No phase listed Observational

Registry of Avive® Soft Tissue Membrane Utilization in Selected Applications of Acute Trauma of the Upper Extremity

NCT03943134
View directory record Official record
Conditions
Acute Upper Extremity Trauma
Interventions
Minimally Processed Human Umbilical Cord Membrane, Standard Surgical Procedures
Other
Lead sponsor
Axogen Corporation
Industry
Eligibility
5 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Tampa, Florida • Indianapolis, Indiana • Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Jun 26, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional

Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

NCT07225582
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Interventions
Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Not applicable Interventional

Physical Therapy on Non-structural Medial Elbow Pain

NCT05537636
View directory record Official record
Conditions
Elbow Injuries and Disorders, Neuritis, Ulnar, Neuritis, Brachial, Neuritis; Nerve Root, Neuritis Median Nerve
Interventions
Rehabiltiation using exercise and manual therapy
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
15 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Jun 26, 2026, 2:12 AM EDT
Completed Phase 2 Interventional

Sham Device, Pill Placebo or Treatment For Arm Pain

NCT00029497
View directory record Official record
Conditions
Cumulative Trauma Disorders, Repetitive Strain Injury, Carpal Tunnel Syndrome, Pain
Interventions
Acupuncture, Amitriptyline
Procedure · Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Jun 26, 2026, 2:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain

NCT04060875
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction, Complex Regional Pain Syndromes, Phantom Limb Pain, Rheumatoid Arthritis, Carpal Tunnel Syndrome, Repetitive Strain Injury
Interventions
Karuna Labs Virtual Reality Software
Device
Lead sponsor
Karuna Labs Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Jun 26, 2026, 2:12 AM EDT