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ClinicalTrials.gov public records Last synced Oct 25, 2026, 12:13 PM EDT

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Showing 601–624 of 686 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peripheral Neuropathic Pain Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Peer Support for Patients With Diabetic Foot Ulcers

NCT06004219
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetes Complications, Peripheral Neuropathy
Interventions
Peer counseling group
Behavioral
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
3
States / cities
Downey, California • Los Angeles, California • Pomona, California
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral Neuropathy

NCT01041859
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Tapentadol extended release (ER), Placebo
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
60
States / cities
Mobile, Alabama • Chandler, Arizona • Mesa, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2013 · Synced Oct 25, 2026, 12:13 PM EDT
Recruiting No phase listed Observational

Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for Treatment of Chronic Pelvic Pain: HOPE Trial

NCT06413277
View directory record Official record
Conditions
Chronic Pelvic Pain, Pudendal Neuralgia
Interventions
Saluda Evoke Smart SCS System
Device
Lead sponsor
Ainsworth Institute of Pain Management
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Not applicable Interventional

Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis

NCT01052571
View directory record Official record
Conditions
Low Back Pain
Interventions
lumbar transforaminal epidural injections
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 4 Interventional

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

NCT00904202
View directory record Official record
Conditions
Postherpetic Neuralgia, Diabetic Neuropathy, Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, HIV Neuropathy, Idiopathic Sensory Neuropathy, Peripheral Neuropathy
Interventions
Placebo Capsules + Placebo Patch, Placebo capsules + Lidoderm®, Gabapentin + Placebo, Gabapentin + Lidoderm®, Gabapentin 300 mg capsules 1800 mg/day + placebo patch, Gabapentin 1800 mg/day + Lidoderm patch
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
7
States / cities
Birmingham, Alabama • Hueytown, Alabama • Phoenix, Arizona + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 25, 2026, 12:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain

NCT04060875
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction, Complex Regional Pain Syndromes, Phantom Limb Pain, Rheumatoid Arthritis, Carpal Tunnel Syndrome, Repetitive Strain Injury
Interventions
Karuna Labs Virtual Reality Software
Device
Lead sponsor
Karuna Labs Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Not applicable Interventional Results available

Combined Peripheral (BreEStim) and Central Electrical Stimulation (tDCS) for Neuropathic Pain Management - Spinal Cord Injury

NCT03302793
View directory record Official record
Conditions
Pain Management
Interventions
BreEStim, tDCS, tDCS sham
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 2 Interventional Results available

A Study for Treatment of Pain in Patients With Diabetic Neuropathy.

NCT00785577
View directory record Official record
Conditions
Diabetic Neuropathy, Painful
Interventions
Placebo, Pregabalin, LY545694 21 mg, LY545694 49 mg, LY545694 105 mg
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 70 Years
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
8
States / cities
Greenbrae, California • Tustin, California • DeLand, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 2 Interventional

Magnets in the Treatment of Sciatica

NCT00044109
View directory record Official record
Conditions
Low Back Pain, Sciatica
Interventions
Magnets
Device
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
30 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 26, 2006 · Synced Oct 25, 2026, 12:13 PM EDT
Not yet recruiting No phase listed Observational

SERENITY Study of Chronic Pain Interference in Adults

NCT07820475
View directory record Official record
Conditions
Chronic Low Back Pain, Spinal Cord Injury, Neuropathic Pain, Chronic Pain, Pain Interference
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 2 Interventional Results available

Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability

NCT01928381
View directory record Official record
Conditions
Diabetic Neuropathy, Painful; Diabetic Neuropathies
Interventions
AZD5213 + pregabalin, Placebo, pregabalin capsules
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
9
States / cities
Clearwater, Florida • Orlando, Florida • Newnan, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain

NCT05022121
View directory record Official record
Conditions
Low Back Pain, Sciatica, Back Related Leg Pain, Pain, Chronic, Intervertebral Disc Displacement
Interventions
Supported Biopsychosocial Self-Management (SBSM), Medical Care
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Not applicable Interventional Results available

Self-Guided Online Cognitive Behavioral Strategies for Chemotherapy-Induced Peripheral Neuropathy

NCT02760654
View directory record Official record
Conditions
Peripheral Nervous System Diseases, Pain Management, Self Management
Interventions
Proactive Self Management Program for Effects of Cancer Treatment
Device
Lead sponsor
University of Michigan
Other
Eligibility
25 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
5
States / cities
Ann Arbor, Michigan • Canton, Michigan • Chelsea, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Oct 25, 2026, 12:13 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Study of Proteins Associated With Complex Regional Pain Syndrome

NCT00033969
View directory record Official record
Conditions
Complex Regional Pain Syndromes, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Use of PET/MR Imaging in Chronic Pain

NCT03195270
View directory record Official record
Conditions
Chronic Pain
Interventions
[18F]FDG, PET/MRI
Drug · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 25, 2026, 12:13 PM EDT
Enrolling by invitation Not applicable Interventional

Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy

NCT07209514
View directory record Official record
Conditions
Diabetic Peripheral Neuropathic Pain (DPN)
Interventions
Implantable SCS with Closed Loop mechanism
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 2 Interventional Results available

Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain

NCT02460692
View directory record Official record
Conditions
Cannabis, Low Back Pain, Neuropathic Pain
Interventions
Placebos, dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
19 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 25, 2026, 12:13 PM EDT
Terminated Not applicable Interventional

Nerve Burial for Preventing Neuralgia After Total Knee Arthroplasty

NCT02885467
View directory record Official record
Conditions
Neuralgia, Osteoarthritis of the Knee
Interventions
Total knee arthroplasty with Saphenous nerve burial, Standard total knee arthroplasty
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Not applicable Interventional Results available

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

NCT01419314
View directory record Official record
Conditions
HIV, AIDS, Peripheral Neuropathy, Pain, Sleep
Interventions
Splinting application to the lower extremities, Splint liner application
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Oct 25, 2026, 12:13 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Role of the Gut Microbiome in Complex Regional Pain Syndrome

NCT03612193
View directory record Official record
Conditions
Complex Regional Pain Syndromes
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Not applicable Interventional

MR Guided Focused Ultrasound for Treatment of Neuropathic Pain

NCT03111277
View directory record Official record
Conditions
Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury, Spinal Cord Injuries, Phantom Limb Pain
Interventions
Experimental: ExAblate Transcranial treatment
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Oct 25, 2026, 12:13 PM EDT
Completed No phase listed Observational

Cost Effectiveness of OMT for Chronic Low Back Pain

NCT03532230
View directory record Official record
Conditions
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis, Lumbar Spondylosis, Lumbago With Sciatica, Left Side, Lumbago With Sciatica, Right Side
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 84 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
East Lansing, Michigan • Stratford, New Jersey • Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 4 Interventional Results available

An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain

NCT00385671
View directory record Official record
Conditions
Diabetic Neuropathy, Painful
Interventions
duloxetine hydrochloride, pregabalin, gabapentin
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
407 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
5
States / cities
Torrance, California • Cromwell, Connecticut • Staten Island, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2011 · Synced Oct 25, 2026, 12:13 PM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy

NCT00857623
View directory record Official record
Conditions
Pain, Diabetic Neuropathy
Interventions
AZD2066, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 80 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
19
States / cities
Bella Vista, Arkansas • National City, California • Walnut Creek, California + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2012 · Synced Oct 25, 2026, 12:13 PM EDT