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ClinicalTrials.gov public records Last synced Oct 14, 2026, 2:05 PM EDT

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Showing 457–480 of 681 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peripheral Vascular Disease (PVD) Clear all
Completed Phase 2 Interventional Results available

Patients With Intermittent Claudication Injected With ALDH Bright Cells

NCT01774097
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
ALD-301, Placebo (vehicle)
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
40 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Stanford, California • Gainesville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study to Evaluate Therapeutic Ultrasound (TUS) to Acutely Increase the Perfusion in Peripheral Arterial Disease (PAD)

NCT05888740
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
VibratoSleeve Therapeutic Ultrasound Device
Device
Lead sponsor
Vibrato Medical, Inc.
Industry
Eligibility
65 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 14, 2026, 2:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Aspirin and Thienopyridine Resistance in Peripheral Arterial Disease

NCT03174990
View directory record Official record
Conditions
Peripheral Arterial Disease, Clopidogrel, Poor Metabolism of
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 1 Interventional

Evaluation of the Effect of the Flowaid Device in Increasing Local Circulation in the Leg

NCT00538226
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
External Electric Muscle Stimulation
Device
Lead sponsor
Rosenblum, Jonathan I., DPM
Individual
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 4 Interventional

A Trial of Alirocumab and Plaque Regression in Peripheral Arterial Disease

NCT02959047
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Alirocumab, Matching placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
35 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 2 Interventional

Safety and Efficacy of K-134 for the Treatment of Intermittent Claudication

NCT00783081
View directory record Official record
Conditions
Intermittent Claudication
Interventions
K-134, Cilostazol 100 mg BID, Placebo
Drug
Lead sponsor
Kowa Research Institute, Inc.
Industry
Eligibility
40 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
30
States / cities
Tucson, Arizona • Little Rock, Arkansas • Beverly Hills, California + 27 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2012 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Safety and Tolerability Study of RJX Drug Product in Healthy Participants

NCT03680105
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
RJX, Placebo
Drug
Lead sponsor
Reven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 1 Interventional

MRI-Guided Balloon Angioplasty to Treat Blood Flow Blockage in the Legs

NCT00094783
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
MRI
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 14, 2026, 2:05 PM EDT
No Longer Available No phase listed Expanded access

Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

NCT03886506
View directory record Official record
Conditions
Critical Limb Ischemia (CLI)
Interventions
PLX-PAD
Biological
Lead sponsor
Pluristem Ltd.
Industry
Eligibility
45 Years to 99 Years
U.S. locations
2
States / cities
Clifton, New Jersey • Teaneck, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 14, 2026, 2:05 PM EDT
Recruiting Not applicable Interventional

Ultrasound Cavitation Therapy for CLI

NCT05749250
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Acoustic cavitation of ultrasound enhancing agents
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Not applicable Interventional

Physical Activity Daily - An Internet-Based Walking Program for Patients With Peripheral Arterial Disease

NCT02022423
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Telephone counseling, Internet-based walking program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
2
States / cities
Birmingham, Alabama • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 21, 2021 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Rehabilitation in Veterans With PAD

NCT02607046
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Exercise training, NMES
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 2 Interventional

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia

NCT01410331
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
JVS-100(4 mg) or placebo/8 injections, JVS-100(8 mg) or placebo/8 injections, JVS-100(8 mg) or placebo/16 injections, JVS-100(16 mg) or placebo/16 injections
Biological
Lead sponsor
Juventas Therapeutics, Inc.
Industry
Eligibility
40 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
5
States / cities
Birmingham, Alabama • Chicago, Illinois • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2014 · Synced Oct 14, 2026, 2:05 PM EDT
Recruiting Not applicable Interventional

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

NCT06321575
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Golazo® Peripheral Atherectomy System (Golazo® Peripheral AS)
Device
Lead sponsor
Nipro Vascular Innovations Americas, Inc
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
20
States / cities
Scottsdale, Arizona • Merced, California • Fort Lauderdale, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 14, 2026, 2:05 PM EDT
Terminated Not applicable Interventional

Prospective Study for the Treatment of Atherosclerotic Lesions in the Superficial Femoral And/or Popliteal Arteries Using the FLEX Scoring Catheter Plus DCB

NCT03676842
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
FLEX Dynamic Scoring Catheter with IN.PACT Admiral DCB
Combination Product
Lead sponsor
VentureMed Group Inc.
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 14, 2026, 2:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Functional MRI of the Lower Extremities

NCT03423316
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Supervised exercise therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 3 Interventional Results available

Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease

NCT03743636
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Nicotinamide riboside, Resveratrol, Placebo
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 2 Interventional

Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease

NCT00113009
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
VLTS-934
Drug
Lead sponsor
Valentis
Industry
Eligibility
40 Years to 78 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
32
States / cities
Birmingham, Alabama • Beverly Hills, California • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Nov 22, 2007 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Not applicable Interventional Results available

The ACTIVE (Use of the Assurant® Cobalt Iliac Stent System in the Treatment of Iliac Vessel Disease) Study

NCT00753337
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Assurant® Cobalt Iliac Stent System
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
2
States / cities
Flint, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Oct 14, 2026, 2:05 PM EDT
Recruiting Phase 4 Interventional

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

NCT06777901
View directory record Official record
Conditions
Peripheral Arterial Diseases
Interventions
Auryon Atherectomy System, Balloon Angioplasty
Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
Not listed
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
9
States / cities
Phoenix, Arizona • San Diego, California • Gray, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 14, 2026, 2:05 PM EDT
Completed No phase listed Observational

Chocolate Balloon Angioplasty Registry

NCT01589042
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Not listed
Lead sponsor
TriReme Medical, LLC
Industry
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
13
States / cities
Phoenix, Arizona • Rancho Mirage, California • Gainesville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 14, 2026, 2:05 PM EDT
Recruiting Not applicable Interventional

EVERO Drug-coated Balloon (DCB) Randomized Trial

NCT07144150
View directory record Official record
Conditions
Peripheral Vascular Disease, Peripheral Arterial Disease
Interventions
Evero DCB, Paclitaxel DCB
Combination Product
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
12
States / cities
Long Beach, California • New Haven, Connecticut • Gainesville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 3 Interventional

Phase III Study of Topical Gel for Treatment and Prevention of Raynaud's Phenomenon

NCT00266669
View directory record Official record
Conditions
Raynaud's Disease
Interventions
Topical organogel with nitroglycerin
Drug
Lead sponsor
MediQuest Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
17
States / cities
Stanford, California • Denver, Colorado • Farmington, Connecticut + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2007 · Synced Oct 14, 2026, 2:05 PM EDT
Completed Phase 2 Interventional

Mixed Antagonist of Serotonin for Claudication Optimal Therapy

NCT00300339
View directory record Official record
Conditions
Intermittent Claudication
Interventions
SL650472, Clopidogrel
Drug
Lead sponsor
Sanofi
Industry
Eligibility
40 Years and older
Enrollment
599 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 19, 2008 · Synced Oct 14, 2026, 2:05 PM EDT