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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Chronic Post-surgical Pain
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Joint (Knee or Hip Replacement)
Interventions
Sleep banking
Behavioral
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 74 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Diego, California
Completed No phase listed Observational Accepts healthy volunteers

Flexibility of Cognition And Persistent Pain

NCT02579538
Conditions
Pain, Postoperative
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Terminated Phase 2 Interventional Accepts healthy volunteers

Duloxetine Impact on Postoperative Pain Control and Outcomes

NCT05611749
Conditions
Acute Post-operative Pain, Chronic Post Operative Pain, Narcotic Use, Opioid Use, Opioid Addiction
Interventions
Duloxetine 60 MG, Placebo
Drug · Other
Lead sponsor
Scripps Health
Other
Eligibility
24 Years to 99 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
La Jolla, California
Conditions
Pain, Surgery, Post Operative Pain
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Scar, Cesarean Section; Dehiscence
Interventions
Scar Deactivation Surface Release Technique protocol, Scar Infiltration with 0.25-1% Lidocaine, Physical therapy
Other
Lead sponsor
Jennifer Loomis
Federal
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Completed No phase listed Observational Accepts healthy volunteers

Characterization of PostOp Pain in Shoulder and Knee Arthroscopy

NCT03047434
Conditions
Post Surgical Pain
Interventions
Not listed
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Not applicable Interventional

PREventing Pain After Surgery

NCT05306665
Conditions
Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis, Spondylolisthesis, Back Injuries
Interventions
ACT intervention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Conditions
Persistent Postsurgical Pain, Breast Cancer Female, Ductal Carcinoma in Situ
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Katherine Hadlandsmyth
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Breast Cancer Surgery Pain, Breast Cancer, Stage 0-III Breast Cancer
Interventions
Qigong Mind-Body Exercise
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Persistent Post-surgical Pain
Interventions
Yoga, Chronic Pain Health Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery, Knee Injuries, Knee Pain Chronic, Postoperative Pain, Chronic Postoperative Pain
Interventions
SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Redwood City, California
Conditions
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Interventions
Surgical Implantation
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Pain, Postoperative, Scoliosis Idiopathic
Interventions
Gabapentin, Placebo
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Pain, Joint Stiffness
Interventions
Total Knee Arthroplasty
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Completed Not applicable Interventional Results available

High Pain Intervention in Cesarean Sections

NCT01298778
Conditions
Other Chronic Postoperative Pain
Interventions
Duramorph 150, Acetaminophen, Duramorph 300
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
Interventions
Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment
Other
Lead sponsor
KK Women's and Children's Hospital
Government
Eligibility
21 Years to 80 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Personalized Post-Operative Pain Management

NCT06669650
Conditions
Persistent Post Operative Opioid Use, Post-surgical Pain
Interventions
PGx guided personalized post-operative pain management, Oxycodone, Hydromorphone
Other · Drug
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Knoxville, Tennessee
Active, not recruiting Not applicable Interventional

The Perioperative Pain Self-Management Program Trial

NCT04979429
Conditions
Postoperative Pain
Interventions
Perioperative Pain Self-management (PePS)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 100 Years
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Iowa City, Iowa • Minneapolis, Minnesota
Conditions
Chronic Postsurgical Pain
Interventions
Continuous ketamine infusion, Ketamine + Saline, Placebo
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Female only
Enrollment
765 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
14
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Chicago, Illinois + 9 more
Conditions
Pain, Postoperative
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Lumbar Surgery
Interventions
Provant
Device
Lead sponsor
Regenesis Biomedical, Inc.
Industry
Eligibility
22 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
8
States / cities
Birmingham, Alabama • Phoenix, Arizona • Boise, Idaho + 5 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA

NCT04814992
Conditions
Chronic Post-Surgical Pain
Interventions
Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
4
States / cities
Philadelphia, Pennsylvania • Radnor, Pennsylvania