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Showing 1–24 of 162 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Personality Disorder Clear all
Recruiting No phase listed Observational

Triage Survey for Psychiatry Research Eligibility

NCT05800925
View directory record Official record
Conditions
Major Depressive Disorder, Borderline Personality Disorder, Generalized Anxiety Disorder
Interventions
Survey
Other
Lead sponsor
Adams Clinical
Network
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Boston, Massachusetts • Watertown, Massachusetts • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effective Measurement of Risperidone Treatment Outcome for Persons With Borderline Personality Disorder

NCT00204347
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
risperidone
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Homeless Youth Study - Stepping Stone 2.0

NCT03776422
View directory record Official record
Conditions
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Interventions
Mobile self-help intervention
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
16 Years to 25 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional

Psychoeducation of Borderline Patients

NCT01719731
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Education, Non-Education
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

NCT02427672
View directory record Official record
Conditions
Antisocial Behavior, Aggression
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 2, 2026, 6:30 AM EDT
Active, not recruiting No phase listed Observational

Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)

NCT05622045
View directory record Official record
Conditions
Obesity, Body Weight Changes
Interventions
Voice data
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 74 Years
Enrollment
59 participants
Timeline
2023 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 2, 2026, 6:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Changes in Children and Adolescents With Behavioral Problems

NCT00104039
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood, Conduct Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 18 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Sep 2, 2026, 6:30 AM EDT
Completed No phase listed Observational

Testing Digital Breast Tomosynthesis vs. Regular Mammogram in Detecting Breast Cancer in Women Having Screening Mammogram

NCT00535678
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2010 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional

Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder

NCT04306341
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
real time fMRI neurofeedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Influence of Genetics in Pain Sensitivity

NCT00001956
View directory record Official record
Conditions
Healthy, Hyperalgesia, Pain
Interventions
Blood draw, Oral surgery, Tissue biopsy
Procedure
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 29, 2006 · Synced Sep 2, 2026, 6:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

MRI Imaging in Borderline Personality Disorder

NCT00275288
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2010 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

CRT-Guanfacine for SPD

NCT02524899
View directory record Official record
Conditions
Schizotypal Personality Disorder, SPD
Interventions
Cognitive Remediation Therapy, Guanfacine, Placebo
Behavioral · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Phase 2 Interventional

Treatment of Suicidal Women With Borderline Personality Disorder

NCT00183651
View directory record Official record
Conditions
Borderline Personality Disorder, Suicide
Interventions
Standard dialectical behavior therapy (SDBT), Individual DBT with no DBT group sessions (DBT-I), Group Skills DBT with no DBT individual sessions (DBT-S)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 1, 2012 · Synced Sep 2, 2026, 6:30 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults

NCT02225600
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
40 IU Intranasal Oxytocin, Placebo, 24 IU intranasal Oxytocin
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 2, 2026, 6:30 AM EDT
Active, not recruiting Not applicable Interventional

EPI-MINN: Targeting Cognition and Motivation - National

NCT05877716
View directory record Official record
Conditions
Psychosis, Psychosis Nos/Other, Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Prodromal Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Schizophreniform Disorders, Major Depression With Psychotic Features, Unspecified Psychosis, Bipolar Disorder
Interventions
Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care
Device · Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
15 Years to 40 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional

Feasibility Trial of a Lifestyle Intervention for CHR-P

NCT05532683
View directory record Official record
Conditions
Prodromal Schizophrenia, Psychosis, Psychological Disorder, Psychological Stress
Interventions
Health Behaviors Group
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Phase 3 Interventional

Olanzapine in Patients With Borderline Personality Disorder

NCT00091650
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Olanzapine, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
15 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
9
States / cities
Atlanta, Georgia • Marietta, Georgia • Minneapolis, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2006 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional

Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse

NCT03035877
View directory record Official record
Conditions
Antisocial Behavior
Interventions
Multisystemic Therapy-Emerging Adults, Enhanced Treatment as Usual
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
16 Years to 26 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
4
States / cities
Hamden, Connecticut • Hartford, Connecticut • New Haven, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personality Style and Self Compassion in Postpartum Depression: An Online Prevention Study

NCT02813174
View directory record Official record
Conditions
Postpartum Depression
Interventions
Compassionate Mind Training from Compassion-Focused Therapy
Behavioral
Lead sponsor
i4Health
Other
Eligibility
18 Years and older · Female only
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Sep 2, 2026, 6:30 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Multisite Prevention of Conduct Problems (Fast Track)

NCT01653535
View directory record Official record
Conditions
Conduct Disorder, Anti-Social Behavior
Interventions
Fast Track
Behavioral
Lead sponsor
Duke University
Other
Eligibility
6 Years to 8 Years
Enrollment
891 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment of Aggression, Anger and Emotional Dysregulation in Borderline Personality Disorder

NCT00467038
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Dialectical Behavior
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2015 · Synced Sep 2, 2026, 6:30 AM EDT
Not listed Phase 2 Interventional

Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder

NCT01466205
View directory record Official record
Conditions
Cognitive Impairments, Schizotypal Personality Disorder
Interventions
DAR-0100A, Placebo
Drug
Lead sponsor
Larry J. Siever
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2012 · Synced Sep 2, 2026, 6:30 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations

NCT02149823
View directory record Official record
Conditions
Borderline Personality Disorder, BPD, Schizotypal Personality Disorder, SPD, Autism Spectrum Disorder, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
Interventions
Syntocinon 24 Intranasal Units (IU), Syntocinon 40 Intranasal Units (IU), Intranasal Placebo
Drug
Lead sponsor
Maria de las Mercedes Perez Rodriguez
Other
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2022 · Synced Sep 2, 2026, 6:30 AM EDT
Completed Phase 2 Interventional Results available

A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder

NCT04566601
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
BI 1358894, Placebo
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years to 65 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
16
States / cities
Anaheim, California • Temecula, California • Upland, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Sep 2, 2026, 6:30 AM EDT