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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:19 PM EDT

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Showing 313–336 of 1,099 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pervasive Development Disorder Clear all
Terminated Phase 3 Interventional

Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions

NCT03553875
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
Interventions
Memantine Hydrochloride, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed No phase listed Observational

Identifying Biomarkers of Gastro Intestinal Comorbidities in Autism Spectrum Disorder

NCT07744217
View directory record Official record
Conditions
Autism, Gastro Intestinal Diseases
Interventions
Not listed
Lead sponsor
The Center for Discovery
Other
Eligibility
5 Years to 19 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Harris, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional Results available

Teaching Academic Success Skills to Students With Autism Spectrum Disorders in Clinical Setting

NCT03606343
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Teaching Academic Skills to Kids
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 14 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional

Neural Mechanisms of CBT for Anxiety in Autism (Open Pilot Study)

NCT02225808
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Anxiety
Interventions
CBT for anxiety in autism
Behavioral
Lead sponsor
Yale University
Other
Eligibility
8 Years to 14 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional Results available

Transcranial Photobiomodulation for Reducing Autism Symptoms in Children

NCT04660552
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Cognilum TM: Light Treatment Condition
Device
Lead sponsor
JelikaLite LLC
Industry
Eligibility
2 Years to 6 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Phase 1 Interventional

Study of Intranasal Ketamine for Social Impairment in Autism Spectrum Disorder

NCT02611921
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Ketamine, Placebo
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 30 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 23, 2026, 1:19 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Do Motor Synchrony Games Improve Self Regulation?

NCT06647693
View directory record Official record
Conditions
Preschool Child, Executive Function (Cognition)
Interventions
Motor Synchrony Games (MSG)
Behavioral
Lead sponsor
Appalachian State University
Other
Eligibility
2 Years to 5 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Oct 23, 2026, 1:19 PM EDT
Recruiting Not applicable Interventional

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

NCT04545606
View directory record Official record
Conditions
Insomnia Chronic, Autism Spectrum Disorder
Interventions
In-Person CBT for insomnia in children with autism, Remote CBT for insomnia in children with autism, Remote sleep hygiene and related education (SHARE) for insomnia in children with autism
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
6 Years to 12 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Phase 2 Interventional Results available

Fatty Acid Supplementation in Children With ASD (Study 2)

NCT04312932
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
LCPUFA Oil Supplement, Canola Oil Placebo
Drug · Dietary Supplement
Lead sponsor
Sarah Keim
Other
Eligibility
2 Years to 6 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Phase 2 Interventional Results available

Trial to Investigate the Safety and Efficacy of Cannabidiol Oral Solution (GWP42003-P; CBD-OS) in Children and Adolescents With Autism Spectrum Disorder

NCT04745026
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
GWP42003-P, Placebo
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
6 Years to 17 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
12
States / cities
Phoenix, Arizona • La Jolla, California • Los Angeles, California + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional

Aquatic Therapy and Autism Spectrum Disorders

NCT03195244
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Aquatic Physical Therapy
Other
Lead sponsor
Sloan W. Rush, MD
Other
Eligibility
3 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Phase 3 Interventional

Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD

NCT05439616
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Cariprazine, Placebo
Drug
Lead sponsor
AbbVie
Industry
Eligibility
5 Years to 17 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
34
States / cities
Anaheim, California • Imperial, California • Orange, California + 28 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Phase 2 Interventional Results available

Specifying and Treating Anxiety in Autism Research

NCT03279471
View directory record Official record
Conditions
Autism Spectrum Disorder, Anxiety
Interventions
Sertraline, CBT/BIACA, Placebo
Drug · Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
8 Years to 14 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind the Gap (AIR-B3)

NCT03711799
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Access to services via peer coaching
Behavioral
Lead sponsor
Health Resources and Services Administration (HRSA)
Federal
Eligibility
2 Years and older
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Davis, California • Rochester, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional Results available

Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety

NCT03720795
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Stepped Care CBT
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 23, 2026, 1:19 PM EDT
Enrolling by invitation Not applicable Interventional

A Two-Part Intervention to Target Cardiovascular Health

NCT07673172
View directory record Official record
Conditions
Autism, Adverse Childhood Experience, Stress, Cardiovascular (CV) Risk
Interventions
Lifestyle Medicine, Cognitive Behavioral Therapy (CBT), Lifestyle Medicine with CBT Group
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 26 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Phase 2 Interventional

A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism

NCT05187377
View directory record Official record
Conditions
Phelan-McDermid Syndrome, Autism Spectrum Disorder (ASD)
Interventions
Growth Hormone, Saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
2 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 23, 2026, 1:19 PM EDT
Not yet recruiting Phase 2 Interventional

Role of Omega-DEK in Childhood Apraxia of Speech

NCT07216001
View directory record Official record
Conditions
Childhood Apraxia of Speech, Verbal Apraxia, Autism
Interventions
Omega-DEK, L-carnitine, Placebo
Drug
Lead sponsor
Claudia R. Morris
Other
Eligibility
36 Months to 6 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Recruiting Phase 2 Interventional

Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)

NCT06866275
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD)
Interventions
KZ101, Placebo
Drug
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
5 Years to 14 Years · Male only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Orange, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating Georgia Part C Implementation Outcomes

NCT07148258
View directory record Official record
Conditions
Communication Disorder, Childhood, Autism
Interventions
Project ImPACT Training As Usual, Project ImPACT Training Plus Co-Production, Routine Project ImPACT
Other · Behavioral
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism

NCT01768806
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
PLAY Project Intervention for Autism, Special education pre-school
Behavioral
Lead sponsor
Richard Solomon MD, Plc
Other
Eligibility
3 Years to 5 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 23, 2026, 1:19 PM EDT
Recruiting Early Phase 1 Interventional

Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder

NCT06934915
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism Spectrum Disorders, Autistic Disorder, Autism
Interventions
Prednisone, Placebo
Drug
Lead sponsor
Christopher John McDougle, M.D.
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Lexington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional

Improving Hospitalizations for Children With ASD

NCT02339935
View directory record Official record
Conditions
Autism Spectrum Disorder, Autistic Disorder
Interventions
Brief Analogue Functional Analysis, No Brief AFA
Behavioral · Other
Lead sponsor
Vanderbilt University
Other
Eligibility
6 Years to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Oct 23, 2026, 1:19 PM EDT
Completed Not applicable Interventional Results available

Mindfulness for Parents of Children With Autism Spectrum Disorder Autism Spectrum Disorder

NCT03459625
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Mindfulness-Based Stress Reduction (MSBR), Psychoeducational Support Group (PE)
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 5 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 23, 2026, 1:19 PM EDT