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ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:36 PM EDT

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Showing 337–360 of 1,099 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pervasive Development Disorder Clear all
Completed No phase listed Observational Accepts healthy volunteers

Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder

NCT02700074
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
No Intervention
Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
14 Years to 21 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional

Mindfulness Training and Parent-coaching Interventions for Autism Spectrum Disorder

NCT03889821
View directory record Official record
Conditions
Autism Spectrum Disorder, Parents, Stress
Interventions
Parent-implemented Early Start Denver Model, Mindfulness Based Stress Reduction
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
12 Months and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional

Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems

NCT00889538
View directory record Official record
Conditions
Autism, Severe Behavior Disorder
Interventions
placebo, glutathione, glutathione, vit C and NAC
Drug
Lead sponsor
University of Louisville
Other
Eligibility
5 Years to 16 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

NCT02028247
View directory record Official record
Conditions
Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified, Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder
Interventions
Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 13 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Phase 1Phase 2 Interventional

Early Pharmacotherapy Aimed at Neuroplasticity in Autism : Safety and Efficacy

NCT00166621
View directory record Official record
Conditions
Autism
Interventions
Buspirone
Drug
Lead sponsor
Chugani, Diane C.
Individual
Eligibility
2 Years to 6 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Oct 23, 2026, 3:36 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers

NCT01172509
View directory record Official record
Conditions
Autism
Interventions
R-baclofen
Drug
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
18 Years to 30 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2015 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional Results available

Mentorship Program for Individuals With Autism Spectrum Disorder (ASD)

NCT05300295
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Mentoring Program
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
14 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 21, 2022 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Phase 2 Interventional Results available

Intranasal Oxytocin Treatment for Social Deficits in Children With Autism

NCT01624194
View directory record Official record
Conditions
Autism
Interventions
Oxytocin nasal spray, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
6 Years to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 23, 2026, 3:36 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners

NCT07384156
View directory record Official record
Conditions
Literacy, Communication, Nonverbal
Interventions
ALLSTAR
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
5 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Early Phase 1 Interventional

Predicting Treatment Response to Memantine in Autism Using Magnetic Resonance Spectroscopy

NCT02811627
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Memantine, Magnetic Resonance Imaging
Drug · Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
16 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Oct 23, 2026, 3:36 PM EDT
Active, not recruiting Phase 2 Interventional

Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders

NCT03408886
View directory record Official record
Conditions
Autism Spectrum Disorder, Gastrointestinal Disorder
Interventions
Vancomycin, MoviPrep, Full Spectrum Microbiota
Drug · Biological
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 60 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Oct 23, 2026, 3:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Early Detection of Autism Spectrum Disorder in Children

NCT01646866
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
St. Louis University
Other
Eligibility
6 Months to 36 Months
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 23, 2026, 3:36 PM EDT
Recruiting Not applicable Interventional

Using a Smart Inhaler to Support Asthma Management in Adolescents With Intellectual and Developmental Disabilities

NCT06783101
View directory record Official record
Conditions
Asthma in Children, Intellectual Disabilities (F70-F79), Developmental Disability, Autism Spectrum Disorder (ASD)
Interventions
Use of smart inhaler to enhance asthma inhaler proficiency
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional

Weight Management Intervention for Youth and Young Adults With Autism Spectrum Disorder

NCT03865719
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Healthy Habits for Life
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
8 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Phase 2 Interventional Results available

Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)

NCT01525901
View directory record Official record
Conditions
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Interventions
Insulin-Like Growth Factor-1 (IGF-1), Normal saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
5 Years to 12 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2022 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Early Phase 1 Interventional

Study of Neuroimaging Biomarkers of Social Cognition Deficits in Adolescents (Age 13-17) With Autism Spectrum Disorder and Effects of Gabapentin

NCT03589898
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Gabapentin
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
13 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional

Strengthening Skills Behavioral Intervention for Adults With Autism Spectrum Disorder

NCT04802434
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Strengthening Skills Program, PEERS Social Skills Program
Behavioral
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
21 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 23, 2026, 3:36 PM EDT
Completed No phase listed Observational

Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress

NCT02442115
View directory record Official record
Conditions
Autistic Disorder, Constipation, Gastrointestinal Diseases
Interventions
Treatment of Functional Constipation by
Other
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
5 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Los Angeles, California • Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Oct 23, 2026, 3:36 PM EDT
Not listed No phase listed Observational

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

NCT05751525
View directory record Official record
Conditions
Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD, Autism Spectrum Disorder, Epilepsy
Interventions
Sulfonylurea
Drug
Lead sponsor
Royal Devon and Exeter NHS Foundation Trust
Other
Eligibility
2 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Oct 23, 2026, 3:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

STEPS Implementation Trial

NCT05695885
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
STEPS, Services as usual (SAU)
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
16 Years to 25 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional Results available

An Open-Label Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders

NCT01850355
View directory record Official record
Conditions
Autism Spectrum Disorders, Anxiety
Interventions
Buspirone
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telehealth Coaching for Families of Children With Autism

NCT02928068
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Occupational Performance Coaching (OPC)
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
12 Months to 84 Months
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 23, 2026, 3:36 PM EDT
Completed Not applicable Interventional

Treatment of Feeding Problems in Children With Autism

NCT02275715
View directory record Official record
Conditions
Treatment of Feeding Problems in Children With ASD
Interventions
Parent Training Program
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
2 Years to 7 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Gainesville, Florida • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 23, 2026, 3:36 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sensory Processing Difficulties in Adults and Adolescents

NCT02205658
View directory record Official record
Conditions
Sensory Processing Dysfunction
Interventions
Not listed
Lead sponsor
The Spiral Foundation at OTA Watertown
Other
Eligibility
13 Years to 95 Years
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Oct 23, 2026, 3:36 PM EDT