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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:57 PM EDT

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Showing 361–384 of 1,099 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pervasive Development Disorder Clear all
Not yet recruiting Phase 2 Interventional

Clinical Trial Evaluating the Effects of Ganaxolone in Children With Autism

NCT07635862
View directory record Official record
Conditions
Autism in Children, Autistic Disorder in Children and Adolescents, Autism Spectrum Disorder
Interventions
Ganaxolone (Ztalmy), Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 17 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Short-term Parent Mediated Social Training on Developmental Trajectories in Infants

NCT03404505
View directory record Official record
Conditions
Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay, Signs of Communication Delay, Signs of Social Delay
Interventions
Infant Achievements, Caregiver Education (CE)
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
8 Months to 12 Months
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 23, 2026, 4:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Validity of a Genetic Risk Assessment Tool in Identifying Autism Spectrum Disorder

NCT01452061
View directory record Official record
Conditions
Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Developmental Delay
Interventions
Not listed
Lead sponsor
Thomas W. Frazier, Ph.D
Other
Eligibility
1 Year to 12 Years
Enrollment
456 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 29, 2014 · Synced Oct 23, 2026, 4:57 PM EDT
Withdrawn Phase 2 Interventional

Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders

NCT01395953
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD)
Interventions
Buspirone, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2024 · Synced Oct 23, 2026, 4:57 PM EDT
Recruiting Phase 2 Interventional

TB006 for Autism Spectrum Disorder

NCT06500637
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
TB006
Drug
Lead sponsor
Rossignol Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Phoenix, Arizona • Aliso Viejo, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 4:57 PM EDT
Withdrawn Phase 2 Interventional

Mercury Chelation to Treat Autism

NCT00376194
View directory record Official record
Conditions
Autism, Asperger's Disorder, Child Development Disorders, Pervasive
Interventions
DMSA
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
4 Years to 10 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2013 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Oxcarbazepine Versus Placebo in Childhood Autism

NCT00467753
View directory record Official record
Conditions
Autism
Interventions
Oxcarbazepine, Placebo/sugar pill
Drug · Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
5 Years to 17 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Efficacy of the ASPEN Intervention Program in Low-Resource Communities

NCT04505488
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
ASD Screening Parent ENgagement Intervention Program (ASPEN)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Months to 6 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Gaming for Autism to Mold Executive Skills Project

NCT02361762
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Computerized executive control training
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 11 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Effectiveness and Implementation of a Mental Health Intervention for ASD

NCT02416323
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
AIM HI Training
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
5 Years to 13 Years
Enrollment
609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

Acamprosate in Youth With Fragile X Syndrome

NCT01300923
View directory record Official record
Conditions
Fragile X Syndrome, Autism Spectrum Disorders
Interventions
Acamprosate
Drug
Lead sponsor
Indiana University
Other
Eligibility
5 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Oct 23, 2026, 4:57 PM EDT
Not listed Phase 2Phase 3 Interventional

Telehealth-Enabled Versus In-Person Parent-Mediated Behavioral Treatment for Challenging Behaviors in Children With ASD

NCT05268796
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Behavior therapy, Psychoeducation
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 7 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Stanford, California • Alamogordo, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 23, 2026, 4:57 PM EDT
Completed No phase listed Observational

DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

NCT03718910
View directory record Official record
Conditions
DDX3X, Mental Retardation, X-linked 102, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
2 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring Predictors of Response to a Peer-Mediated Intervention for Preschoolers With ASD

NCT05277103
View directory record Official record
Conditions
Autism Spectrum Disorder, Nonverbal Communication
Interventions
Exploring predictors of response to a peer-mediated communication intervention for minimally verbal preschoolers with ASD
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
3 Years to 6 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Phase 2 Interventional

AB-2004 in Treatment of Irritability Associated With Autism Spectrum Disorder (ASD)

NCT04895215
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD)
Interventions
AB-2004, Placebo
Drug
Lead sponsor
Vertero Therapeutics
Industry
Eligibility
5 Years to 17 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
18
States / cities
Dothan, Alabama • Phoenix, Arizona • Tucson, Arizona + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional

A Bicycle Training Intervention

NCT02046889
View directory record Official record
Conditions
Autism Spectrum Disorder, Down Syndrome
Interventions
Bicycle Training Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
9 Years to 18 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Southbend, Indiana • Ann Arbor, Michigan • Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study 1 Replication and Extension of Prior Work

NCT04166591
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Overheard Speech, Addressed Speech
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Months to 71 Months
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Providing Accessible Diagnostic Evaluations and Psychoeducation for Autism Spectrum Disorder in Rural Southwest Virginia

NCT05822921
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
In-person Psychoeducation (IP), Telehealth Psychoeducation (TH), Psychoeducation as Usual (PAU)
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
16 Months to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Blacksburg, Virginia • Wytheville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 23, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder

NCT06006637
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Cognilum TM: Light Treatment Condition
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
2 Years to 8 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
New York, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Structured Function-Based Elopement Treatment Program

NCT03899831
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Function-Based Elopement Treatment (FBET), Parent Education Program (PEP)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
4 Years to 12 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Oct 23, 2026, 4:57 PM EDT
Not listed Not applicable Interventional

Self-Advocacy Training for Autistic College Students at a Public University

NCT05450536
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Video Model and Role Play
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 22 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Phase 3 Interventional

Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.

NCT00399698
View directory record Official record
Conditions
Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit/Hyperactivity Disorder (ADHD), Intermittent Explosive Disorder, Impulse-Control Disorders, Adjustment Disorder, Bipolar Disorder, Pervasive Developmental Disorder
Interventions
Risperdal
Drug
Lead sponsor
Ohio State University
Other
Eligibility
4 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 23, 2016 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ESCAPE Kits for Elopement Prevention in Children With Autism

NCT07225907
View directory record Official record
Conditions
Autism Spectrum Disorder, Child Safety, Caregiver Stress
Interventions
Elopement Prevention Kits
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
4 Years to 11 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 23, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Effects of Hyperbaric Oxygen Therapy in Autistic Children: A Pilot Study

NCT00324909
View directory record Official record
Conditions
Autism, Oxidative Stress, Inflammation
Interventions
Hyperbaric Oxygen Therapy
Drug
Lead sponsor
International Hyperbarics Association
Other
Eligibility
2 Years to 18 Years
Enrollment
18 participants
U.S. locations
1
States / cities
Arrington, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 10, 2007 · Synced Oct 23, 2026, 4:57 PM EDT