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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pervasive Development Disorder Clear all
Completed Phase 2 Interventional

Ziprasidone in Children With Autism: A Pilot Study

NCT00208559
View directory record Official record
Conditions
Autism
Interventions
Ziprasidone
Drug
Lead sponsor
Drexel University College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2010 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Primary Care Stepping Stones Triple P for Children With Autism

NCT02236650
View directory record Official record
Conditions
Autism
Interventions
Primary Care Stepping Stones Triple P (PC-SS Triple P), Treatment as Usual
Behavioral · Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Jul 22, 2026, 10:14 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Hyperbaric Oxygen Therapy on Cognitive Function on Autistic Spectrum Disordered Children

NCT00631215
View directory record Official record
Conditions
Cognition
Interventions
Hyperbaric oxygen therapy
Procedure
Lead sponsor
Pediatric Partners of Ponte Vedra
Other
Eligibility
6 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Ponte Vedra Beach, Florida
Source: ClinicalTrials.gov public record
Updated Mar 6, 2008 · Synced Jul 22, 2026, 10:14 AM EDT
Terminated Phase 2 Interventional Results available

Translating Neuroprediction Into Precision Medicine Via Brain Priming

NCT03370510
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Oxytocin, Pivotal Response Treatment, Placebo
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
5 Years to 9 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin/Mineral Supplement for Children With Autism

NCT04845776
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
ANRC Essentials Plus
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 8, 2023 · Synced Jul 22, 2026, 10:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Extracellular Signal-Related Kinase Biomarker Development in Autism

NCT01850459
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 25 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Efficacy of the ASPEN Intervention Program in Low-Resource Communities

NCT04505488
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
ASD Screening Parent ENgagement Intervention Program (ASPEN)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Months to 6 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 22, 2026, 10:14 AM EDT
Active, not recruiting Not applicable Interventional

Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD

NCT05131659
View directory record Official record
Conditions
Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
Interventions
Executive function group therapy
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
14 Years to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 22, 2026, 10:14 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Facing Your Fears: Adolescents With ASD and Intellectual Disability

NCT05131425
View directory record Official record
Conditions
Autism Spectrum Disorder, Intellectual Disability, Anxiety, Emotion Regulation
Interventions
Facing Your Fears: ASD/ID, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent Training to Enhance Social Success for Children With Autism Spectrum Disorder

NCT03177525
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Social SUCCESS, Wait List
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 6 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Phase 2 Interventional Results available

Treatment of Rett Syndrome With Recombinant Human IGF-1

NCT01777542
View directory record Official record
Conditions
Rett Syndrome
Interventions
Recombinant Human Insulin Growth Factor 1 (rhIGF-1), Placebo
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 10 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 25, 2018 · Synced Jul 22, 2026, 10:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Autism Biomarker Consortium for Clinical Trials (ABC-CT): Follow-up Study

NCT04841525
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
6 Years to 11 Years
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Effects of Drugs on Responses to Brain and Emotional Processes

NCT04053036
View directory record Official record
Conditions
Autism Spectrum Disorder, Healthy
Interventions
MDMA, Placebo oral tablet
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Jul 22, 2026, 10:14 AM EDT
Not yet recruiting Phase 3 Interventional

A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder

NCT07285798
View directory record Official record
Conditions
Irritability Associated With Autism Spectrum Disorder
Interventions
KarXT, KarX-EC, KarXT + KarX-EC Matching Placebo
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
5 Years to 17 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
19
States / cities
Phoenix, Arizona • Glendale, California • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Phase 3 Interventional Results available

Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)

NCT01825798
View directory record Official record
Conditions
Overweight, Autism Spectrum Disorder
Interventions
Metformin, Placebo
Drug
Lead sponsor
Holland Bloorview Kids Rehabilitation Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Columbus, Ohio • Pittsburgh, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children

NCT00178503
View directory record Official record
Conditions
Autism, Attention Deficit Disorder With Hyperactivity
Interventions
Methylphenidate-extended release, Methylphenidate-immediate release, Placebo
Drug · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
7 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2013 · Synced Jul 22, 2026, 10:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings

NCT04199533
View directory record Official record
Conditions
Autism Spectrum Disorder, Disruptive Behavior
Interventions
RUBI, RUBIES
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Jul 22, 2026, 10:14 AM EDT
Completed No phase listed Observational

Study to Compare Verbal Scores of Children Diagnosed With ASD Who Received Hyperbaric Treatment To Those Who Did Not

NCT06043284
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Hyperbaric Oxygen Therapy
Device
Lead sponsor
Oxford Recovery Center
Other
Eligibility
2 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Brighton, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jul 22, 2026, 10:14 AM EDT
Completed No phase listed Observational

Pediatric Patients With Metabolic or Other Genetic Disorders

NCT02769949
View directory record Official record
Conditions
Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome, Developmental Delay
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
1 Year to 99 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent-Mediated Intervention for Families With Children With Autism and Feeding Challenges

NCT03071120
View directory record Official record
Conditions
Parent-Child Relations, Meals, Autism Spectrum Disorder
Interventions
Parent-Mediated Intervention
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
2 Years to 7 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 7, 2023 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Not applicable Interventional Results available

Expert Guiding Technology to Help Individuals With Developmental Challenges Build Life and Vocational Skills

NCT04518358
View directory record Official record
Conditions
Autism Spectrum Disorder, Intellectual Disability
Interventions
Use of Expert Guiding Technology (GAINS) to Improve Live and Vocational Skills for Individuals with Developmental Challenges
Behavioral
Lead sponsor
John T. Nosek
Industry
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Jul 22, 2026, 10:14 AM EDT
Enrolling by invitation Not applicable Interventional

Mobile App-Based Intervention to Improve Toothbrushing in Children and Teens With Autism

NCT07446413
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Brush Up App, Brush Down App
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
8 Years to 17 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 22, 2026, 10:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach

NCT05453708
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related, Diet, Healthy, Diet; Deficiency, Folate Deficiency, Folic Acid Deficiency, Folic Acid Overdose
Interventions
Survey
Other
Lead sponsor
Walden University
Other
Eligibility
18 Years and older · Female only
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2023 · Synced Jul 22, 2026, 10:14 AM EDT
Completed Early Phase 1 Interventional

Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD

NCT02874690
View directory record Official record
Conditions
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Methylphenidate, Placebo
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years to 21 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Jul 22, 2026, 10:14 AM EDT