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ClinicalTrials.gov public records Last synced Oct 30, 2026, 4:54 AM EDT

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Showing 985–1008 of 1,102 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pervasive Development Disorder Clear all
Completed Not applicable Interventional

Treating Oxidative Stress and the Metabolic Pathology of Autism

NCT00572741
View directory record Official record
Conditions
Autistic Disorder
Interventions
B12, Placebo, folate, B complex, vitamin C, cod liver oil, Mineral complex, carnitine
Dietary Supplement
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
3 Years to 7 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 5, 2016 · Synced Oct 30, 2026, 4:54 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effectiveness of the Autism Pupil Screen (APS) Detect Pupillometer for Identifying Autism Spectrum Disorder (ASD) in Routine Healthcare

NCT07903675
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Autism Pupil Screen (APS) Detect PLR Assessment #1, Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT/R-F), Social Responsiveness Scale, Second Edition (SRS-2), Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Mullen Scales of Early Learning (MSEL), Adaptive Behavior Assessment System, Third Edition (ABAS-3), Autism Pupil Screen (APS) Detect PLR Assessment #2, Autism Pupil Screen (APS) Detect Assessment #3, Well-child check
Device · Other · Diagnostic Test + 1 more
Lead sponsor
Schweitzer Engineering Laboratories
Industry
Eligibility
24 Months to 60 Months
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
4
States / cities
Lewiston, Idaho • Moscow, Idaho • Pullman, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Oct 30, 2026, 4:54 AM EDT
Completed No phase listed Observational

A Longitudinal Study on the Safety and Efficacy for Subjects With ASD Who Received MeRT

NCT02746445
View directory record Official record
Conditions
Autistic Disorder
Interventions
No intervention
Other
Lead sponsor
Wave Neuroscience
Industry
Eligibility
6 Years to 15 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 30, 2026, 4:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exosomal MicroRNA Expression in Children With Autism Spectrum Disorder

NCT01749670
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
4 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2014 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stepped-care Telehealth for Young Children With ASD

NCT04467073
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Online RIT
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
16 Months to 60 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 10, 2020 · Synced Oct 30, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

Effectiveness- Implementation Trial of the Function-Based Elopement Treatment

NCT07194083
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Function-Based Elopement Treatment, Treatment as Usual
Behavioral
Lead sponsor
Emory University
Other
Eligibility
4 Years to 12 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 30, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

Differences in Rest, Emotion, and Arousal Modulation in Youth

NCT07476937
View directory record Official record
Conditions
Autism, Sleep Disturbances in Children, Sleep
Interventions
Power Down bedtime manipulation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
6 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 30, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms

NCT07214545
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
Interventions
Trigeminal Nerve Stimulation, Sham Trigeminal Nerve Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 14 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 30, 2026, 4:54 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Transcranial Ultrasonography Using Linear 2D Imaging of the Brain

NCT01980186
View directory record Official record
Conditions
Autism, Extra-axial Fluid
Interventions
TUS transcranial 2D ultrasound
Device
Lead sponsor
Brain Treatment Center
Other
Eligibility
6 Months to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
2
States / cities
Newport Beach, California • Buford, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 11, 2013 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

NCT03170453
View directory record Official record
Conditions
Autistic Disorder, Autism Spectrum Disorder, Asperger Syndrome, Pervasive Developmental Disorder
Interventions
Cognitive Enhancement Therapy, Enriched Supportive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 45 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families

NCT03307057
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition, Usual Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
6 Months to 6 Months
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 30, 2026, 4:54 AM EDT
Withdrawn Phase 2 Interventional

Intranasal Oxytocin and Learning in Autism

NCT02090829
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Syntocinon (synthetic oxytocin), Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools

NCT01724047
View directory record Official record
Conditions
Autism
Interventions
Playground Intervention, STAT Intervention
Behavioral
Lead sponsor
Health Resources and Services Administration (HRSA)
Federal
Eligibility
4 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
3
States / cities
Los Angeles, California • Rochester, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Phase 3 Interventional Results available

A Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder

NCT02985749
View directory record Official record
Conditions
Autism Spectrum Disorder, Pervasive Developmental Disorder, ASD, PDD
Interventions
Intranasal Oxytocin
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Pivotal Response Group Treatment for Parents of Young Children With Autism

NCT01881750
View directory record Official record
Conditions
Autistic Disorder
Interventions
Pivotal Response Training (PRT), Parent Education Group (PEG)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 6 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2019 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Phase 4 Interventional Results available

Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

NCT02096952
View directory record Official record
Conditions
Attention-deficit/Hyperactivity Disorder, Autism Spectrum Disorder
Interventions
Methylphenidate extended-release liquid formulation
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Photobiomodulation in Autism Spectrum Disorder (ASD)

NCT03724552
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Transcranial LED Therapy (Participants ages 9-17), Transcranial LED Therapy (Participants ages 18-59)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
9 Years to 59 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Oct 30, 2026, 4:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Incredible Years Program for Parents of Children with Autism

NCT03300128
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Incredible Years - ASD, Circle of Parents
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Jacksonville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 30, 2026, 4:54 AM EDT
Not listed Not applicable Interventional

JASPER Early Intervention for Tuberous Sclerosis

NCT03422367
View directory record Official record
Conditions
Tuberous Sclerosis
Interventions
JASPER
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
6 Months to 40 Months
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2020 · Synced Oct 30, 2026, 4:54 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Optimizing Outcomes for Young Autistic Children

NCT05926687
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Social Communication, Disruptive Behavior, Social Communication + Reduce Frequency, Social Communication + Add Tools, Disruptive Behavior + Reduce Frequency, Disruptive Behavior + Add Tools
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Months to 48 Months
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Stimulus-Stimulus Pairing Study

NCT02464527
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Stimulus-stimulus pairing, Vocal recorder
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
24 Months to 47 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 15, 2016 · Synced Oct 30, 2026, 4:54 AM EDT
Terminated Not applicable Interventional Results available

Memantine in Adult Autism Spectrum Disorder

NCT01078844
View directory record Official record
Conditions
Autism, Asperger's Disorder, Pervasive Developmental Disorder NOS
Interventions
memantine, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 26, 2017 · Synced Oct 30, 2026, 4:54 AM EDT
Completed Phase 1 Interventional

Use of MRI and cTBS for Catatonia in Autism

NCT06016764
View directory record Official record
Conditions
Autism Spectrum Disorder, Catatonia, Intellectual Disability
Interventions
Continuous Theta Burst in Transcranial Magnetic Stimulation
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
15 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 31, 2025 · Synced Oct 30, 2026, 4:54 AM EDT
Not listed Phase 3 Interventional

Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances

NCT05361707
View directory record Official record
Conditions
Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance
Interventions
Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
2 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
San Jose, California • San Leandro, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 30, 2026, 4:54 AM EDT