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Showing 1–24 of 248 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder.

NCT06037668
View directory record Official record
Conditions
Social Anxiety Disorder (SAD)
Interventions
BVR-100, BES-100
Device
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Orlando, Florida • Boston, Massachusetts • Saint Charles, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 2, 2026, 4:11 PM EDT
Withdrawn Phase 1 Interventional

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

NCT05429788
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Low dose RLS103, High dose RLS103, placebo inhaled dry powder
Drug
Lead sponsor
Receptor Life Sciences
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Los Angeles, California • Oceanside, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Sep 2, 2026, 4:11 PM EDT
Recruiting Not applicable Interventional

Behavioral Exposure for Introceptive Tolerance RCT

NCT05398276
View directory record Official record
Conditions
Exercise Sensitivity, Introceptive Exposure, Anxiety, Cardiac Rehabilitation
Interventions
Behavioral Exposure For Introceptive Tolerance, Health Education Control
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
East Brunswick, New Jersey • Hillsborough, New Jersey • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional

Effects of Therapeutic Mobile Game on Anxiety

NCT05240794
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
ABM-01, Digital Control
Device
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
22 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional Results available

Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety

NCT03720795
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Stepped Care CBT
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional

Virtual Reality for Youth Phobias

NCT05839431
View directory record Official record
Conditions
Specific Phobia, Social Anxiety Disorder, Autism Spectrum Disorder
Interventions
Virtual Reality for Youth Phobias
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
8 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

tDCS-Augmented Exposure Therapy for Pathological Fear

NCT03095482
View directory record Official record
Conditions
Specific Phobias
Interventions
Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2020 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 4 Interventional Results available

D-Cycloserine Enhancement of Exposure in Social Phobia

NCT00633984
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Cognitive Behavioral Group Therapy (CBGT), D-Cycloserine, Placebo
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional

One-session Treatment for Spider Fears

NCT03410264
View directory record Official record
Conditions
Spider Phobia
Interventions
CR-EXP, EXP-CR, Stress Management
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 7, 2021 · Synced Sep 2, 2026, 4:11 PM EDT
Not listed Not applicable Interventional

The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catastrophizing, Kinesiophobia, and Pain in Patients With Chronic Low Back Pain

NCT05571215
View directory record Official record
Conditions
Chronic Low-back Pain, Catastrophizing Pain, Kinesiophobia
Interventions
Transcranial Direct Current Stimulation, Pain Neuroscience Education
Device · Behavioral
Lead sponsor
High Point University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 2Phase 3 Interventional

St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD)

NCT00118833
View directory record Official record
Conditions
Anxiety Disorders, Mental Health
Interventions
Hypericum perforatum (St. John's wort)
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2007 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 4 Interventional Results available

Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder

NCT00282828
View directory record Official record
Conditions
Social Phobia
Interventions
Sertraline, Venlafaxine, Placebo, Clonazepam
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
La Jolla, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2013 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional

Cognitive Training for Mood and Anxiety Disorders

NCT02256566
View directory record Official record
Conditions
Major Depressive Disorder, Depression, Bipolar Disorder, Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Social Phobia
Interventions
emotional memory training exercise, memory training exercise
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 2, 2026, 4:11 PM EDT
Enrolling by invitation Not applicable Interventional

Interactive E-Learning for Therapist Training in Exposure Therapy

NCT07379853
View directory record Official record
Conditions
Therapist Training, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Interventions
Therapist Training
Other
Lead sponsor
Bradley Hospital
Other
Eligibility
21 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hormones and Social Anxiety Disorder Treatment

NCT02482805
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years to 70 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Enhancing Exposure Therapy for Snake and Spider Phobias

NCT02160470
View directory record Official record
Conditions
Specific Phobia
Interventions
Exposure Therapy with Retrieval, Exposure Therapy with Compound Extinction, Exposure Therapy with Retrieval and Compound Extinction, Therapist-guided Exposure Therapy
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2020 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional Results available

Reduction of Claustrophobia and Patient Motion After Training of MRI Personnel in Comfort TalkTM

NCT01563198
View directory record Official record
Conditions
Claustrophobia, Complication of Diagnostic Procedure
Interventions
Comfort Talk®
Behavioral
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
Not listed
Enrollment
97,712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Brookline, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 2, 2026, 4:11 PM EDT
Terminated Phase 4 Interventional Results available

A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder

NCT03078270
View directory record Official record
Conditions
Anxiety Disorder Social, Anxiety
Interventions
botulinum toxin A, Placebo
Drug · Other
Lead sponsor
Daniel Lieberman
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 1Phase 2 Interventional

Treatment Study for Rural Latino Youth With Anxiety

NCT01491880
View directory record Official record
Conditions
Anxiety Disorders, Separation Anxiety Disorder, Social Anxiety Disorder, Specific Phobia, Generalized Anxiety Disorder
Interventions
Therapist-Assisted by Telephone, Self-Help
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 13 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional

Brief Shame Intervention Study

NCT03463356
View directory record Official record
Conditions
Shame, Social Anxiety Disorder
Interventions
Shame Intervention
Behavioral
Lead sponsor
Miami University
Other
Eligibility
18 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Oxford, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 2 Interventional

St. John's Wort Versus Placebo in Social Phobia

NCT00035412
View directory record Official record
Conditions
Phobic Disorders
Interventions
St. John's Wort
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Not applicable Interventional

Using Immersive Virtual Reality to Treat Pediatric Anxiety

NCT04504773
View directory record Official record
Conditions
Specific Phobia, Specific Phobia, Situational, Specific Phobia, Animal, Specific Phobia, Natural Environment, Childhood Anxiety Disorder
Interventions
Virtual Reality Exposure Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Sep 2, 2026, 4:11 PM EDT
Recruiting Not applicable Interventional

Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.

NCT06934525
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety, OCD, Phobia, Agoraphobia, Generalized Anxiety, Generalized Anxiety Disorder, Selective Mutism, Separation Anxiety, Social Anxiety, Social Anxiety Disorder, Panic Disorder, Pediatric Disorders
Interventions
Team-delivered, exposure-based CBT
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 2, 2026, 4:11 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder

NCT03017508
View directory record Official record
Conditions
Social Anxiety Disorder, Performance Anxiety
Interventions
BHV-0223, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Sep 2, 2026, 4:11 PM EDT